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Normative Study to Correlate the Effects of Morphological Variables on Macular and Choroidal Thickness Using SD-OCT

Received: 2 January 2019     Accepted: 21 January 2019     Published: 13 February 2019
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Abstract

To determine macular and choroidal thickness in healthy north Indian eyes and determine its variation with age and height using SD-OCT. The macula of 400 randomly selected healthy subjects (800 eyes) with no retinal and choroidal pathology was imaged with Cirrus SD-OCT. Macular thickness from all 9 regions of Early Treatment Diabetic Retinopathy Study was evaluated. Choroid was visualized by enhanced depth imaging technique. Choroidal thickness was measured sub foveally and at 500 microns intervals upto 1500 microns temporal and nasal to the fovea. The mean age of the subjects was 33.60 years ± 14.033 and mean height was 163.5 cms ± 11.715. Mean central macular thickness (CMT) was 242.59 µm ± 16.802 and mean sub foveal choroidal thickness was 325.18 µm ± 47.087. CMT correlated significantly (Pearson’s correlation coefficient) with age (r=0.120, p<0.001) and height (r=0.258, p<0.001). Choroidal thickness decreased with age and the correlation was statistically significant. Choroidal thickness also decreased with height with a statistically significant correlation, but no specific pattern was found. This normative database of choroidal and macular thickness by OCT will serve as baseline for diagnosing retinal pathologies and help in future research.

Published in International Journal of Ophthalmology & Visual Science (Volume 4, Issue 1)
DOI 10.11648/j.ijovs.20190401.11
Page(s) 1-6
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Choroidal Thickness, Macular Thickness, Normative Study, Spectral-Domain Optical Coherence Tomography (SD-OCT), North Indian

References
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    Sumeet Chopra, Preet Kanwar Singh Sodhi, Akash Deep Goel, Sehajpreet Kaur, Gurkirat Singh Bajwa. (2019). Normative Study to Correlate the Effects of Morphological Variables on Macular and Choroidal Thickness Using SD-OCT. International Journal of Ophthalmology & Visual Science, 4(1), 1-6. https://doi.org/10.11648/j.ijovs.20190401.11

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    ACS Style

    Sumeet Chopra; Preet Kanwar Singh Sodhi; Akash Deep Goel; Sehajpreet Kaur; Gurkirat Singh Bajwa. Normative Study to Correlate the Effects of Morphological Variables on Macular and Choroidal Thickness Using SD-OCT. Int. J. Ophthalmol. Vis. Sci. 2019, 4(1), 1-6. doi: 10.11648/j.ijovs.20190401.11

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    AMA Style

    Sumeet Chopra, Preet Kanwar Singh Sodhi, Akash Deep Goel, Sehajpreet Kaur, Gurkirat Singh Bajwa. Normative Study to Correlate the Effects of Morphological Variables on Macular and Choroidal Thickness Using SD-OCT. Int J Ophthalmol Vis Sci. 2019;4(1):1-6. doi: 10.11648/j.ijovs.20190401.11

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  • @article{10.11648/j.ijovs.20190401.11,
      author = {Sumeet Chopra and Preet Kanwar Singh Sodhi and Akash Deep Goel and Sehajpreet Kaur and Gurkirat Singh Bajwa},
      title = {Normative Study to Correlate the Effects of Morphological Variables on Macular and Choroidal Thickness Using  SD-OCT},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {4},
      number = {1},
      pages = {1-6},
      doi = {10.11648/j.ijovs.20190401.11},
      url = {https://doi.org/10.11648/j.ijovs.20190401.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20190401.11},
      abstract = {To determine macular and choroidal thickness in healthy north Indian eyes and determine its variation with age and height using SD-OCT. The macula of 400 randomly selected healthy subjects (800 eyes) with no retinal and choroidal pathology was imaged with Cirrus SD-OCT. Macular thickness from all 9 regions of Early Treatment Diabetic Retinopathy Study was evaluated. Choroid was visualized by enhanced depth imaging technique. Choroidal thickness was measured sub foveally and at 500 microns intervals upto 1500 microns temporal and nasal to the fovea. The mean age of the subjects was 33.60 years ± 14.033 and mean height was 163.5 cms ± 11.715. Mean central macular thickness (CMT) was 242.59 µm ± 16.802 and mean sub foveal choroidal thickness was 325.18 µm ± 47.087. CMT correlated significantly (Pearson’s correlation coefficient) with age (r=0.120, p<0.001) and height (r=0.258, p<0.001). Choroidal thickness decreased with age and the correlation was statistically significant. Choroidal thickness also decreased with height with a statistically significant correlation, but no specific pattern was found. This normative database of choroidal and macular thickness by OCT will serve as baseline for diagnosing retinal pathologies and help in future research.},
     year = {2019}
    }
    

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    AU  - Sumeet Chopra
    AU  - Preet Kanwar Singh Sodhi
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    AB  - To determine macular and choroidal thickness in healthy north Indian eyes and determine its variation with age and height using SD-OCT. The macula of 400 randomly selected healthy subjects (800 eyes) with no retinal and choroidal pathology was imaged with Cirrus SD-OCT. Macular thickness from all 9 regions of Early Treatment Diabetic Retinopathy Study was evaluated. Choroid was visualized by enhanced depth imaging technique. Choroidal thickness was measured sub foveally and at 500 microns intervals upto 1500 microns temporal and nasal to the fovea. The mean age of the subjects was 33.60 years ± 14.033 and mean height was 163.5 cms ± 11.715. Mean central macular thickness (CMT) was 242.59 µm ± 16.802 and mean sub foveal choroidal thickness was 325.18 µm ± 47.087. CMT correlated significantly (Pearson’s correlation coefficient) with age (r=0.120, p<0.001) and height (r=0.258, p<0.001). Choroidal thickness decreased with age and the correlation was statistically significant. Choroidal thickness also decreased with height with a statistically significant correlation, but no specific pattern was found. This normative database of choroidal and macular thickness by OCT will serve as baseline for diagnosing retinal pathologies and help in future research.
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Author Information
  • Department of Ophthalmology, Dayanand Medical College and Hospital, Baba Farid University of Health Sciences, Ludhiana, India

  • Department of Vitreo-Retina, Sodhi Eye Hospital, Patiala, India

  • Department of Cornea, LV Prasad Eye Institute, Hyderabad, India

  • Department of Ophthalmology, Dayanand Medical College and Hospital, Baba Farid University of Health Sciences, Ludhiana, India

  • Department of Ophthalmology, Dayanand Medical College and Hospital, Baba Farid University of Health Sciences, Ludhiana, India

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