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A Combined Clinical and Langmuir Film Study of Natural Tear Films

Received: 2 February 2017     Accepted: 23 February 2017     Published: 9 March 2017
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Abstract

The Langmuir technique has been applied to the study of natural tears and the results obtained from surface pressure-area isotherms have been correlated with those of clinical tests (the Schirmer and the TFBUT tests). The population studied only included people aged over 45. Natural tears were collected from Schirmer strips, which were placed in contact with the water subphase of a Langmuir trough for recording the surface pressure-area isotherms. These isotherms have been classified as good or weak according to the characteristics obtained. From the isotherms, characteristic values such as πlimit, CS-1max and πmax were also obtained. The analysis from the Chi-squared test indicates dependence between the Schirmer test and the type of isotherms (P<0.05). In the case of the TFBUT test and the type of isotherms the value of P>0.05 indicates that the independence cannot be discarded with the significance criteria imposed. Working with the same criteria of significance, we obtain moderate or good Pearson correlation coefficients with statistical significance (P<0.05) between the values of the Schirmer test and the πlimit, CS-1max and πmax values. On the other hand, we obtain low Pearson correlation coefficients with no statistical significance (P>0.05) between the values of the TFBUT test and the πlimit, CS-1max and πmax values.

Published in International Journal of Ophthalmology & Visual Science (Volume 2, Issue 1)
DOI 10.11648/j.ijovs.20170201.13
Page(s) 5-14
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Natural Tears, Surface Pressure-Area Isotherm, Elastic Modulus, Schirmer Test, Tear Film Break-Up-Time (TFBUT)

References
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Cite This Article
  • APA Style

    Ester Guaus, Carla Fàbregas, Miriam Pérez, Juan Torrent-Burgués. (2017). A Combined Clinical and Langmuir Film Study of Natural Tear Films. International Journal of Ophthalmology & Visual Science, 2(1), 5-14. https://doi.org/10.11648/j.ijovs.20170201.13

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    ACS Style

    Ester Guaus; Carla Fàbregas; Miriam Pérez; Juan Torrent-Burgués. A Combined Clinical and Langmuir Film Study of Natural Tear Films. Int. J. Ophthalmol. Vis. Sci. 2017, 2(1), 5-14. doi: 10.11648/j.ijovs.20170201.13

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    AMA Style

    Ester Guaus, Carla Fàbregas, Miriam Pérez, Juan Torrent-Burgués. A Combined Clinical and Langmuir Film Study of Natural Tear Films. Int J Ophthalmol Vis Sci. 2017;2(1):5-14. doi: 10.11648/j.ijovs.20170201.13

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  • @article{10.11648/j.ijovs.20170201.13,
      author = {Ester Guaus and Carla Fàbregas and Miriam Pérez and Juan Torrent-Burgués},
      title = {A Combined Clinical and Langmuir Film Study of Natural Tear Films},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {2},
      number = {1},
      pages = {5-14},
      doi = {10.11648/j.ijovs.20170201.13},
      url = {https://doi.org/10.11648/j.ijovs.20170201.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20170201.13},
      abstract = {The Langmuir technique has been applied to the study of natural tears and the results obtained from surface pressure-area isotherms have been correlated with those of clinical tests (the Schirmer and the TFBUT tests). The population studied only included people aged over 45. Natural tears were collected from Schirmer strips, which were placed in contact with the water subphase of a Langmuir trough for recording the surface pressure-area isotherms. These isotherms have been classified as good or weak according to the characteristics obtained. From the isotherms, characteristic values such as πlimit, CS-1max and πmax were also obtained. The analysis from the Chi-squared test indicates dependence between the Schirmer test and the type of isotherms (P<0.05). In the case of the TFBUT test and the type of isotherms the value of P>0.05 indicates that the independence cannot be discarded with the significance criteria imposed. Working with the same criteria of significance, we obtain moderate or good Pearson correlation coefficients with statistical significance (P<0.05) between the values of the Schirmer test and the πlimit, CS-1max and πmax values. On the other hand, we obtain low Pearson correlation coefficients with no statistical significance (P>0.05) between the values of the TFBUT test and the πlimit, CS-1max and πmax values.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - A Combined Clinical and Langmuir Film Study of Natural Tear Films
    AU  - Ester Guaus
    AU  - Carla Fàbregas
    AU  - Miriam Pérez
    AU  - Juan Torrent-Burgués
    Y1  - 2017/03/09
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ijovs.20170201.13
    DO  - 10.11648/j.ijovs.20170201.13
    T2  - International Journal of Ophthalmology & Visual Science
    JF  - International Journal of Ophthalmology & Visual Science
    JO  - International Journal of Ophthalmology & Visual Science
    SP  - 5
    EP  - 14
    PB  - Science Publishing Group
    SN  - 2637-3858
    UR  - https://doi.org/10.11648/j.ijovs.20170201.13
    AB  - The Langmuir technique has been applied to the study of natural tears and the results obtained from surface pressure-area isotherms have been correlated with those of clinical tests (the Schirmer and the TFBUT tests). The population studied only included people aged over 45. Natural tears were collected from Schirmer strips, which were placed in contact with the water subphase of a Langmuir trough for recording the surface pressure-area isotherms. These isotherms have been classified as good or weak according to the characteristics obtained. From the isotherms, characteristic values such as πlimit, CS-1max and πmax were also obtained. The analysis from the Chi-squared test indicates dependence between the Schirmer test and the type of isotherms (P<0.05). In the case of the TFBUT test and the type of isotherms the value of P>0.05 indicates that the independence cannot be discarded with the significance criteria imposed. Working with the same criteria of significance, we obtain moderate or good Pearson correlation coefficients with statistical significance (P<0.05) between the values of the Schirmer test and the πlimit, CS-1max and πmax values. On the other hand, we obtain low Pearson correlation coefficients with no statistical significance (P>0.05) between the values of the TFBUT test and the πlimit, CS-1max and πmax values.
    VL  - 2
    IS  - 1
    ER  - 

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Author Information
  • Faculty of Optics and Optometry, Department of Chemical Engineering, Universitat Politècnica de Catalunya, C/ Violinista Vellsolà, Terrassa (Barcelona), Spain

  • Faculty of Optics and Optometry, Department of Chemical Engineering, Universitat Politècnica de Catalunya, C/ Violinista Vellsolà, Terrassa (Barcelona), Spain

  • Faculty of Optics and Optometry, Department of Chemical Engineering, Universitat Politècnica de Catalunya, C/ Violinista Vellsolà, Terrassa (Barcelona), Spain

  • Faculty of Optics and Optometry, Department of Chemical Engineering, Universitat Politècnica de Catalunya, C/ Violinista Vellsolà, Terrassa (Barcelona), Spain

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