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Quantitative Analysis of Diffusion Weighted MR Images of Intracerebral Haemorrhage by Signal Intensity Gradient Technique

Received: 28 July 2013     Published: 20 August 2013
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Abstract

Intracerebral Haemorrhage (ICH) is an important public health problem leading to high rates of death and disability in adults. Early and reliable identification of the stage of ICH is vital when choosing the proper treatment and estimating patient’s diagnosis and outcome. Diffusion Weighted - Magnetic Resonance Imaging (DW-MRI) presents a variation in the image signal intensity characteristics relative to the different stages of ICH and thus an increased understanding of the progression of the signal intensity variations on Diffusion Weighted (DW) images, subsequent to the onset of ICH, is valuable. In the present paper an effort was made to quantify the variations in the signal intensity characteristics on DW images, at evolving stages of ICH, for 32 subjects, by means of Signal Intensity Gradient (SIG) imaging metric. The relative increase in the SIG values (RSIG) for the subjects with ICH was in the range of (3.83 – 35.67) times compared to their corresponding SIG values on the contralateral normal side. The observed RSIG values were elevated in Stage 1 (Hyperacute: <1 day) and further progressively decreased in Stage 2 (Acute: 1 - 7 days) and Stage 3 (Late subacute: 7 - 14 days), and eventually reached their minimum in Stage 4 (Chronic: >14 days) of ICH. Also a negative correlation (r = − 0.97) was observed between the RSIG values and the evolving stages of ICH. Therefore, the progression of the RSIG values could be supportive in understanding the developmental stages of ICH, and further be helpful in predicting the ICH stage and providing treatment at the appropriate time.

Published in International Journal of Medical Imaging (Volume 1, Issue 1)
DOI 10.11648/j.ijmi.20130101.13
Page(s) 12-18
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2013. Published by Science Publishing Group

Keywords

Diffusion Weighted Images, Intracerebral Haemorrhage, Magnetic Resonance Imaging, Signal Intensity Gradient

References
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    Supriya S. Shanbhag, Gururaj R. Udupi, K. Mothiram Patil, Krishnaswamy Ranganath. (2013). Quantitative Analysis of Diffusion Weighted MR Images of Intracerebral Haemorrhage by Signal Intensity Gradient Technique. International Journal of Medical Imaging, 1(1), 12-18. https://doi.org/10.11648/j.ijmi.20130101.13

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    ACS Style

    Supriya S. Shanbhag; Gururaj R. Udupi; K. Mothiram Patil; Krishnaswamy Ranganath. Quantitative Analysis of Diffusion Weighted MR Images of Intracerebral Haemorrhage by Signal Intensity Gradient Technique. Int. J. Med. Imaging 2013, 1(1), 12-18. doi: 10.11648/j.ijmi.20130101.13

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    AMA Style

    Supriya S. Shanbhag, Gururaj R. Udupi, K. Mothiram Patil, Krishnaswamy Ranganath. Quantitative Analysis of Diffusion Weighted MR Images of Intracerebral Haemorrhage by Signal Intensity Gradient Technique. Int J Med Imaging. 2013;1(1):12-18. doi: 10.11648/j.ijmi.20130101.13

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  • @article{10.11648/j.ijmi.20130101.13,
      author = {Supriya S. Shanbhag and Gururaj R. Udupi and K. Mothiram Patil and Krishnaswamy Ranganath},
      title = {Quantitative Analysis of Diffusion Weighted MR Images of Intracerebral Haemorrhage by Signal Intensity Gradient Technique},
      journal = {International Journal of Medical Imaging},
      volume = {1},
      number = {1},
      pages = {12-18},
      doi = {10.11648/j.ijmi.20130101.13},
      url = {https://doi.org/10.11648/j.ijmi.20130101.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20130101.13},
      abstract = {Intracerebral Haemorrhage (ICH) is an important public health problem leading to high rates of death and disability in adults. Early and reliable identification of the stage of ICH is vital when choosing the proper treatment and estimating patient’s diagnosis and outcome. Diffusion Weighted - Magnetic Resonance Imaging (DW-MRI) presents a variation in the image signal intensity characteristics relative to the different stages of ICH and thus an increased understanding of the progression of the signal intensity variations on Diffusion Weighted (DW) images, subsequent to the onset of ICH, is valuable. In the present paper an effort was made to quantify the variations in the signal intensity characteristics on DW images, at evolving stages of ICH, for 32 subjects, by means of Signal Intensity Gradient (SIG) imaging metric. The relative increase in the SIG values (RSIG) for the subjects with ICH was in the range of (3.83 – 35.67) times compared to their corresponding SIG values on the contralateral normal side. The observed RSIG values were elevated in Stage 1 (Hyperacute: 14 days) of ICH. Also a negative correlation (r = − 0.97) was observed between the RSIG values and the evolving stages of ICH. Therefore, the progression of the RSIG values could be supportive in understanding the developmental stages of ICH, and further be helpful in predicting the ICH stage and providing treatment at the appropriate time.},
     year = {2013}
    }
    

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  • TY  - JOUR
    T1  - Quantitative Analysis of Diffusion Weighted MR Images of Intracerebral Haemorrhage by Signal Intensity Gradient Technique
    AU  - Supriya S. Shanbhag
    AU  - Gururaj R. Udupi
    AU  - K. Mothiram Patil
    AU  - Krishnaswamy Ranganath
    Y1  - 2013/08/20
    PY  - 2013
    N1  - https://doi.org/10.11648/j.ijmi.20130101.13
    DO  - 10.11648/j.ijmi.20130101.13
    T2  - International Journal of Medical Imaging
    JF  - International Journal of Medical Imaging
    JO  - International Journal of Medical Imaging
    SP  - 12
    EP  - 18
    PB  - Science Publishing Group
    SN  - 2330-832X
    UR  - https://doi.org/10.11648/j.ijmi.20130101.13
    AB  - Intracerebral Haemorrhage (ICH) is an important public health problem leading to high rates of death and disability in adults. Early and reliable identification of the stage of ICH is vital when choosing the proper treatment and estimating patient’s diagnosis and outcome. Diffusion Weighted - Magnetic Resonance Imaging (DW-MRI) presents a variation in the image signal intensity characteristics relative to the different stages of ICH and thus an increased understanding of the progression of the signal intensity variations on Diffusion Weighted (DW) images, subsequent to the onset of ICH, is valuable. In the present paper an effort was made to quantify the variations in the signal intensity characteristics on DW images, at evolving stages of ICH, for 32 subjects, by means of Signal Intensity Gradient (SIG) imaging metric. The relative increase in the SIG values (RSIG) for the subjects with ICH was in the range of (3.83 – 35.67) times compared to their corresponding SIG values on the contralateral normal side. The observed RSIG values were elevated in Stage 1 (Hyperacute: 14 days) of ICH. Also a negative correlation (r = − 0.97) was observed between the RSIG values and the evolving stages of ICH. Therefore, the progression of the RSIG values could be supportive in understanding the developmental stages of ICH, and further be helpful in predicting the ICH stage and providing treatment at the appropriate time.
    VL  - 1
    IS  - 1
    ER  - 

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Author Information
  • Department of Electronics and Communication Engineering, Gogte Institute of Technology, Belgaum, Karnataka, India

  • Vishwanathrao Deshpande Rural Institute of Technology, Haliyal, Karnataka, India

  • Retired, Indian Institute of Technology (Madras), Belgaum, Karnataka, India

  • RAGAVS Diagnostics and Research Center Pvt. Ltd., Bangalore, Karnataka, India

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