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The Significance of Prebiotics and Immuno-Nutrients for Assuring the Developmental Milestones in Toddlerhood

Received: 27 June 2024     Accepted: 15 July 2024     Published: 6 August 2024
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Abstract

The immune system development of children is influenced by the mother's nutritional state throughout pregnancy as well as the nutrients the unborn kid is exposed to through nursing and other meals. Micronutrients that are important for the development of the immune system in neonates include iron, zinc, and vitamins A, C, D, and E. both probiotics and prebiotics are essential for maintaining a healthy gut microbiota and a robust immune system. While probiotics directly add beneficial bacteria to the gut, prebiotics serve as food for these bacteria, enhancing their growth and activity. Together, they play a vital role in supporting immune function and overall health. Prebiotics also play a significant role in this process by acting as fertilizers to encourage the growth of healthy bacteria in the stomach. Micronutrient deficiencies (MNDs) have an effect on the developing immune system; therefore, a meeting of specialists was arranged to talk about preventative and mitigating strategies. Immunological responses are largely determined by nutrition, and malnutrition is the leading cause of immunodeficiency worldwide. Protein-energy deprivation is associated with a significant decline in cell-mediated immunity, phagocyte activity, complement system, secretory immunoglobulin an antibody concentration, and cytokine production. Certain nutrient deficits cause altered immune responses, even in cases when the deficiency is fairly mild. The immune responses are significantly influenced by micronutrients such as folic acid, zinc, selenium, iron, copper, and vitamins A, C, E, and B-6. Additionally, overeating and obesity reduce immunity. Low birth weight babies' cell-mediated immunity is permanently compromised; this can be somewhat restored by adding more zinc to their diets. Prebiotics are inactive dietary ingredients that, when combined with immuno-nutrients, benefit the host by encouraging the growth and/or activity of a certain kind of bacteria in the colon. Government, development partners, non-governmental organizations, and academia must collaborate to increase the availability of basic and effective nutrition interventions, as well as those that address more stifling issues. These interventions include exclusive breastfeeding, appropriate supplemental feeding, micronutrient supplementation for children, adolescents, pregnant women, and lactating women, managing severe acute malnutrition and deworming, and hygiene interventions. The entire healthcare system needs to be revitalized in order to get over the obstacles that exist at the levels of policy, governance, and service delivery and to create demand for the services at the household level. Priority should also be devoted to stabilizing food prices and managing nutrition following natural disasters.

Published in International Journal of Immunology (Volume 12, Issue 3)
DOI 10.11648/j.iji.20241203.11
Page(s) 38-47
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Immunity, Micronutrients, Macronutrients, Prebiotics, Nutritional Problems, Maternal Nutrition, Child Nutrition

References
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Cite This Article
  • APA Style

    Yeasmin, S., Islam, M., Ara, C., Amin, R., Islam, N., et al. (2024). The Significance of Prebiotics and Immuno-Nutrients for Assuring the Developmental Milestones in Toddlerhood. International Journal of Immunology, 12(3), 38-47. https://doi.org/10.11648/j.iji.20241203.11

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    ACS Style

    Yeasmin, S.; Islam, M.; Ara, C.; Amin, R.; Islam, N., et al. The Significance of Prebiotics and Immuno-Nutrients for Assuring the Developmental Milestones in Toddlerhood. Int. J. Immunol. 2024, 12(3), 38-47. doi: 10.11648/j.iji.20241203.11

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    AMA Style

    Yeasmin S, Islam M, Ara C, Amin R, Islam N, et al. The Significance of Prebiotics and Immuno-Nutrients for Assuring the Developmental Milestones in Toddlerhood. Int J Immunol. 2024;12(3):38-47. doi: 10.11648/j.iji.20241203.11

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  • @article{10.11648/j.iji.20241203.11,
      author = {Shahida Yeasmin and Manirul Islam and Chaman Ara and Ruhul Amin and Nazrul Islam and Liaquat Ali},
      title = {The Significance of Prebiotics and Immuno-Nutrients for Assuring the Developmental Milestones in Toddlerhood
    },
      journal = {International Journal of Immunology},
      volume = {12},
      number = {3},
      pages = {38-47},
      doi = {10.11648/j.iji.20241203.11},
      url = {https://doi.org/10.11648/j.iji.20241203.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20241203.11},
      abstract = {The immune system development of children is influenced by the mother's nutritional state throughout pregnancy as well as the nutrients the unborn kid is exposed to through nursing and other meals. Micronutrients that are important for the development of the immune system in neonates include iron, zinc, and vitamins A, C, D, and E. both probiotics and prebiotics are essential for maintaining a healthy gut microbiota and a robust immune system. While probiotics directly add beneficial bacteria to the gut, prebiotics serve as food for these bacteria, enhancing their growth and activity. Together, they play a vital role in supporting immune function and overall health. Prebiotics also play a significant role in this process by acting as fertilizers to encourage the growth of healthy bacteria in the stomach. Micronutrient deficiencies (MNDs) have an effect on the developing immune system; therefore, a meeting of specialists was arranged to talk about preventative and mitigating strategies. Immunological responses are largely determined by nutrition, and malnutrition is the leading cause of immunodeficiency worldwide. Protein-energy deprivation is associated with a significant decline in cell-mediated immunity, phagocyte activity, complement system, secretory immunoglobulin an antibody concentration, and cytokine production. Certain nutrient deficits cause altered immune responses, even in cases when the deficiency is fairly mild. The immune responses are significantly influenced by micronutrients such as folic acid, zinc, selenium, iron, copper, and vitamins A, C, E, and B-6. Additionally, overeating and obesity reduce immunity. Low birth weight babies' cell-mediated immunity is permanently compromised; this can be somewhat restored by adding more zinc to their diets. Prebiotics are inactive dietary ingredients that, when combined with immuno-nutrients, benefit the host by encouraging the growth and/or activity of a certain kind of bacteria in the colon. Government, development partners, non-governmental organizations, and academia must collaborate to increase the availability of basic and effective nutrition interventions, as well as those that address more stifling issues. These interventions include exclusive breastfeeding, appropriate supplemental feeding, micronutrient supplementation for children, adolescents, pregnant women, and lactating women, managing severe acute malnutrition and deworming, and hygiene interventions. The entire healthcare system needs to be revitalized in order to get over the obstacles that exist at the levels of policy, governance, and service delivery and to create demand for the services at the household level. Priority should also be devoted to stabilizing food prices and managing nutrition following natural disasters.
    },
     year = {2024}
    }
    

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    VL  - 12
    IS  - 3
    ER  - 

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Author Information
  • Department of Paediatric, Rajshahi Medical College & Hospital, Rajshahi, Bangladesh

  • Department of Neonatology, Rajshahi Medical College & Hospital, Rajshahi, Bangladesh

  • Department of Neonatology, Rajshahi Medical College & Hospital, Rajshahi, Bangladesh

  • Department of Paediatric, Rajshahi Medical College & Hospital, Rajshahi, Bangladesh

  • Department of Paediatric, Shahid Ziaur Rahman Medical, College Hospital, Bogura, Bangladesh

  • Department of Paediatric, North Bengal Medical College & Hospital, Rajshahi, Bangladesh

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