| Peer-Reviewed

Vulnerability to Psychosis in Cannabis Users: The Case of Two Pairs of Brothers

Received: 9 May 2016     Accepted: 3 June 2016     Published: 20 June 2016
Views:       Downloads:
Abstract

In some recent papers, it have been suggested the influence of genetic factors as an important factor into the development of psychotic symptoms and/or psychotic disorder in patients with drug use. In the current paper, we show the history of two pairs of brothers using drug, with psychotic symptoms and /or psychotic disorder and distinct outcome after several years

Published in International Journal of Dual Diagnosis (Volume 1, Issue 2)
DOI 10.11648/j.ijdd.20160102.11
Page(s) 14-16
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Cannabis, Genetics, Psychosis, Schizophrenia

References
[1] Arseneault L, Cannon M, Poulton R, Murray R, Caspi A, Moffitt TE. (2002) Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study. BMJ. 23; 325 (7374): 1212-3
[2] Bowers MB Jr. (1998) Family history and early psychotogenic response to marijuana. J Clin Psychiatry. 1998 Apr; 59 (4): 198-9
[3] Bowers MB, Kantrowitz JT (2007) Elevated Plasma Dopamine Metabolites in Cannabis Psychosis. Am J Psychiatry Psychosis, 164 (10): 1615-1616
[4] Bowers MB: (1996) Chronic substance-induced psychotic disorders: state of the literature. J Neuropsy Clin Neurosc, 8 (3): 262-269
[5] Caspi A, Moffitt TE, Cannon M, McClay J, Murray R, Harrington H, Taylor A, Arseneault L, Williams B, Braithwaite A, Poulton R, Craig IW. (2005) Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction. Biol Psychiatry, 15; 57 (10): 1117-27
[6] Di Forti M, Iyegbe C, Sallis H, Kolliakou A, Falcone MA, Paparelli A, Sirianni M, La Cascia C, Stilo SA, Marques TR, Handley R, Mondelli V, Dazzan P, Pariante C, David AS, Morgan C, Powell J, Murray RM. (2012) Biol Psychiatry. 15; 72 (10): 811-6
[7] Fernández-Ruiz JJ, Romero J, García L, García Palomero E, Ramos JA (1996) Dopaminergic neurons as substrate of neurobehavioral effects of marihuana: Developmental and adult studies. En: Beninger RJ, Palomo T, Archer T, eds. Dopamine disease states. Editorial CYM, Madrid
[8] Gold MS, Bowers MB (1978) Neurobiological vulnerability to low-dose amphetamine psychosis. Am J Psychiatry, 135: 1546-1548
[9] McGuire PK, Jones P, Harvey I, Williams M, McGuffin P, Murray RM (1995) Morbid risk of schizophrenia for relatives of patients with cannabis-induced psychosis. Schizophr Research, 15: 277-281.
[10] Morgan CJ, Freeman TP, Powell J, Curran HV (2016) AKT1 genotype moderates the acute psychotomimetic effects of naturalistically smoked cannabis in young cannabis smokers. Transl Psychiatry. 2016 Feb 16; 6: e 738. doi: 10.1038/tp.2015.219
[11] Moore TH, Zammit S, Lingford-Hughes A, Barnes TR, Jones PB, Burke M, Lewis G. (2007) Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet. 28; 370 (9584): 319-28
[12] Negrete JC (1984) Clinical psychiatric complications of cannabis use: an update. Marihuana Proceedings of the Oxford Symposium on cannabis, Oxford, septiembre: 482-486
[13] Sato MA (1992) A lasting vulnerability to psychosis in patients with previous metamphetamine psychosis. Ann NY Acad Sci, 654: 160-170
[14] Täschner KL (1983) Zur Psychopathologie und differentialdiagnose sogenannter cannabispsychosen. Forrschr Neurol Psychiatr, 51: 235-248
[15] Tsuang MT, Simpson JC, Kronfold Z (1982) Subtypes of drug abuse with psychosis. Arch Gen Psychiatry, 39: 141-147.
[16] Ungerleider JT, Fischer D, Fuller M (1968) The “bad trip”: the etiology of the adverse LSD reaction. Am J Psychiatr, 124: 1483-1490
[17] van Os J, Bak M, Hanssen M, Bijl RV, de Graaf R, Verdoux H. (2002) Cannabis use and psychosis: a longitudinal population-based study. Am J Epidemiol, 15; 156 (4): 319-27
[18] van Os J, Marcelis M. (1998) The ecogenetics of schizophrenia: a review. Schizophr Res. 27; 32 (2): 127-35
[19] Varma SL, Sharma I (1993) Psychiatric comorbidity in first-degree relatives of schizophrenic patients. Br J Psychiatry. 162: 672-678
[20] Zammit S, Owen MJ, Evans J, Heron J, Lewis G. (2011) Cannabis, COMT and psychotic experiences. Br J Psychiatry; 199 (5): 380-5
Cite This Article
  • APA Style

    Núñez Cueto D., Núñez Domínguez L. A. (2016). Vulnerability to Psychosis in Cannabis Users: The Case of Two Pairs of Brothers. International Journal of Dual Diagnosis, 1(2), 14-16. https://doi.org/10.11648/j.ijdd.20160102.11

    Copy | Download

    ACS Style

    Núñez Cueto D.; Núñez Domínguez L. A. Vulnerability to Psychosis in Cannabis Users: The Case of Two Pairs of Brothers. Int. J. Dual Diagn. 2016, 1(2), 14-16. doi: 10.11648/j.ijdd.20160102.11

    Copy | Download

    AMA Style

    Núñez Cueto D., Núñez Domínguez L. A. Vulnerability to Psychosis in Cannabis Users: The Case of Two Pairs of Brothers. Int J Dual Diagn. 2016;1(2):14-16. doi: 10.11648/j.ijdd.20160102.11

    Copy | Download

  • @article{10.11648/j.ijdd.20160102.11,
      author = {Núñez Cueto D. and Núñez Domínguez L. A.},
      title = {Vulnerability to Psychosis in Cannabis Users: The Case of Two Pairs of Brothers},
      journal = {International Journal of Dual Diagnosis},
      volume = {1},
      number = {2},
      pages = {14-16},
      doi = {10.11648/j.ijdd.20160102.11},
      url = {https://doi.org/10.11648/j.ijdd.20160102.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijdd.20160102.11},
      abstract = {In some recent papers, it have been suggested the influence of genetic factors as an important factor into the development of psychotic symptoms and/or psychotic disorder in patients with drug use. In the current paper, we show the history of two pairs of brothers using drug, with psychotic symptoms and /or psychotic disorder and distinct outcome after several years},
     year = {2016}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Vulnerability to Psychosis in Cannabis Users: The Case of Two Pairs of Brothers
    AU  - Núñez Cueto D.
    AU  - Núñez Domínguez L. A.
    Y1  - 2016/06/20
    PY  - 2016
    N1  - https://doi.org/10.11648/j.ijdd.20160102.11
    DO  - 10.11648/j.ijdd.20160102.11
    T2  - International Journal of Dual Diagnosis
    JF  - International Journal of Dual Diagnosis
    JO  - International Journal of Dual Diagnosis
    SP  - 14
    EP  - 16
    PB  - Science Publishing Group
    UR  - https://doi.org/10.11648/j.ijdd.20160102.11
    AB  - In some recent papers, it have been suggested the influence of genetic factors as an important factor into the development of psychotic symptoms and/or psychotic disorder in patients with drug use. In the current paper, we show the history of two pairs of brothers using drug, with psychotic symptoms and /or psychotic disorder and distinct outcome after several years
    VL  - 1
    IS  - 2
    ER  - 

    Copy | Download

Author Information
  • Sections