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Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity

Received: 23 December 2016     Accepted: 10 January 2017     Published: 2 March 2017
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Abstract

The present review covers the recent synthetic amino acid derivatives with chemical transformations to peptide derivatives. The amino acids were used as starting keys for synthesis peptides and pseudopeptides derived from pyridinine, coumarine, imaddizole, pyrazole phthalyl, qunolinine and sulfonamide rings. these biomolecules have diverse biological and pharmacological actions, as antimicrobial, anti-cancer targeting human carbonic anhydrase (CA) and DNA binding activities.

Published in International Journal of Bioorganic Chemistry (Volume 2, Issue 2)
DOI 10.11648/j.ijbc.20170202.11
Page(s) 36-50
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Amino Acid, DNA Binding, Anticancer, Antimicrobial

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  • APA Style

    Ahmed A. Elhenawy. (2017). Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity. International Journal of Bioorganic Chemistry, 2(2), 36-50. https://doi.org/10.11648/j.ijbc.20170202.11

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    ACS Style

    Ahmed A. Elhenawy. Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity. Int. J. Bioorg. Chem. 2017, 2(2), 36-50. doi: 10.11648/j.ijbc.20170202.11

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    AMA Style

    Ahmed A. Elhenawy. Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity. Int J Bioorg Chem. 2017;2(2):36-50. doi: 10.11648/j.ijbc.20170202.11

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  • @article{10.11648/j.ijbc.20170202.11,
      author = {Ahmed A. Elhenawy},
      title = {Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity},
      journal = {International Journal of Bioorganic Chemistry},
      volume = {2},
      number = {2},
      pages = {36-50},
      doi = {10.11648/j.ijbc.20170202.11},
      url = {https://doi.org/10.11648/j.ijbc.20170202.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbc.20170202.11},
      abstract = {The present review covers the recent synthetic amino acid derivatives with chemical transformations to peptide derivatives. The amino acids were used as starting keys for synthesis peptides and pseudopeptides derived from pyridinine, coumarine, imaddizole, pyrazole phthalyl, qunolinine and sulfonamide rings. these biomolecules have diverse biological and pharmacological actions, as antimicrobial, anti-cancer targeting human carbonic anhydrase (CA) and DNA binding activities.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity
    AU  - Ahmed A. Elhenawy
    Y1  - 2017/03/02
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ijbc.20170202.11
    DO  - 10.11648/j.ijbc.20170202.11
    T2  - International Journal of Bioorganic Chemistry
    JF  - International Journal of Bioorganic Chemistry
    JO  - International Journal of Bioorganic Chemistry
    SP  - 36
    EP  - 50
    PB  - Science Publishing Group
    SN  - 2578-9392
    UR  - https://doi.org/10.11648/j.ijbc.20170202.11
    AB  - The present review covers the recent synthetic amino acid derivatives with chemical transformations to peptide derivatives. The amino acids were used as starting keys for synthesis peptides and pseudopeptides derived from pyridinine, coumarine, imaddizole, pyrazole phthalyl, qunolinine and sulfonamide rings. these biomolecules have diverse biological and pharmacological actions, as antimicrobial, anti-cancer targeting human carbonic anhydrase (CA) and DNA binding activities.
    VL  - 2
    IS  - 2
    ER  - 

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Author Information
  • Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt

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