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Effect of Aerobic Exercise on Serum Adiponectin and Serum Malondialdehyde (MDA) In Type 1 Diabetic Patients

Received: 4 August 2017     Accepted: 21 August 2017     Published: 18 September 2017
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Abstract

Type 1 diabetes is fatal unless treated with insulin. Exercise interventions have been shown to be as efficient as the pharmaceutical agents to improve glycaemic control. The aim of the current study was to determine the effect of aerobic exercise on possible mechanisms controlling insulin resistance. Forty diabetic type 1 patients of both sexes (20 females and 20 males) were participated in the study. They were randomly divided into two equal groups. Study group comprised of 20 patients participated in a supervised moderate-intensity aerobic exercise program performed on bicycle ergometer for 50 minutes, 3 times per week, for 8 weeks, in addition to their medical treatment while the control group received only their medical treatment. The result showed that a significant decrease in insulin resistance in the Study group as compared to the control group. The mean values of adiponectin were significantly increased from 5.85±0.65 to 6.6±0.56 in the study group. The mean values of Malondialdehyde (MDA) and fasting glucose were significantly decreased from 7.2±0.98, 146.88±11.42 to 6.45±0.95, 133.87±11.99 respectively in the study group. It can be concluded that aerobic exercise has a positive effect on decreasing insulin resistance and hence decrease the incidence of diabetic complications.

Published in European Journal of Preventive Medicine (Volume 5, Issue 5)
DOI 10.11648/j.ejpm.20170505.14
Page(s) 71-76
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Type 1 Diabetes, Insulin, Aerobic Exercise, Insulin Resistance

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Cite This Article
  • APA Style

    Mai Mohamed Elbalshy, Mariam Elsayed Mohamed, Awny Fouad Rahma. (2017). Effect of Aerobic Exercise on Serum Adiponectin and Serum Malondialdehyde (MDA) In Type 1 Diabetic Patients. European Journal of Preventive Medicine, 5(5), 71-76. https://doi.org/10.11648/j.ejpm.20170505.14

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    ACS Style

    Mai Mohamed Elbalshy; Mariam Elsayed Mohamed; Awny Fouad Rahma. Effect of Aerobic Exercise on Serum Adiponectin and Serum Malondialdehyde (MDA) In Type 1 Diabetic Patients. Eur. J. Prev. Med. 2017, 5(5), 71-76. doi: 10.11648/j.ejpm.20170505.14

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    AMA Style

    Mai Mohamed Elbalshy, Mariam Elsayed Mohamed, Awny Fouad Rahma. Effect of Aerobic Exercise on Serum Adiponectin and Serum Malondialdehyde (MDA) In Type 1 Diabetic Patients. Eur J Prev Med. 2017;5(5):71-76. doi: 10.11648/j.ejpm.20170505.14

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  • @article{10.11648/j.ejpm.20170505.14,
      author = {Mai Mohamed Elbalshy and Mariam Elsayed Mohamed and Awny Fouad Rahma},
      title = {Effect of Aerobic Exercise on Serum Adiponectin and Serum Malondialdehyde (MDA) In Type 1 Diabetic Patients},
      journal = {European Journal of Preventive Medicine},
      volume = {5},
      number = {5},
      pages = {71-76},
      doi = {10.11648/j.ejpm.20170505.14},
      url = {https://doi.org/10.11648/j.ejpm.20170505.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20170505.14},
      abstract = {Type 1 diabetes is fatal unless treated with insulin. Exercise interventions have been shown to be as efficient as the pharmaceutical agents to improve glycaemic control. The aim of the current study was to determine the effect of aerobic exercise on possible mechanisms controlling insulin resistance. Forty diabetic type 1 patients of both sexes (20 females and 20 males) were participated in the study. They were randomly divided into two equal groups. Study group comprised of 20 patients participated in a supervised moderate-intensity aerobic exercise program performed on bicycle ergometer for 50 minutes, 3 times per week, for 8 weeks, in addition to their medical treatment while the control group received only their medical treatment. The result showed that a significant decrease in insulin resistance in the Study group as compared to the control group. The mean values of adiponectin were significantly increased from 5.85±0.65 to 6.6±0.56 in the study group. The mean values of Malondialdehyde (MDA) and fasting glucose were significantly decreased from 7.2±0.98, 146.88±11.42 to 6.45±0.95, 133.87±11.99 respectively in the study group. It can be concluded that aerobic exercise has a positive effect on decreasing insulin resistance and hence decrease the incidence of diabetic complications.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Effect of Aerobic Exercise on Serum Adiponectin and Serum Malondialdehyde (MDA) In Type 1 Diabetic Patients
    AU  - Mai Mohamed Elbalshy
    AU  - Mariam Elsayed Mohamed
    AU  - Awny Fouad Rahma
    Y1  - 2017/09/18
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ejpm.20170505.14
    DO  - 10.11648/j.ejpm.20170505.14
    T2  - European Journal of Preventive Medicine
    JF  - European Journal of Preventive Medicine
    JO  - European Journal of Preventive Medicine
    SP  - 71
    EP  - 76
    PB  - Science Publishing Group
    SN  - 2330-8230
    UR  - https://doi.org/10.11648/j.ejpm.20170505.14
    AB  - Type 1 diabetes is fatal unless treated with insulin. Exercise interventions have been shown to be as efficient as the pharmaceutical agents to improve glycaemic control. The aim of the current study was to determine the effect of aerobic exercise on possible mechanisms controlling insulin resistance. Forty diabetic type 1 patients of both sexes (20 females and 20 males) were participated in the study. They were randomly divided into two equal groups. Study group comprised of 20 patients participated in a supervised moderate-intensity aerobic exercise program performed on bicycle ergometer for 50 minutes, 3 times per week, for 8 weeks, in addition to their medical treatment while the control group received only their medical treatment. The result showed that a significant decrease in insulin resistance in the Study group as compared to the control group. The mean values of adiponectin were significantly increased from 5.85±0.65 to 6.6±0.56 in the study group. The mean values of Malondialdehyde (MDA) and fasting glucose were significantly decreased from 7.2±0.98, 146.88±11.42 to 6.45±0.95, 133.87±11.99 respectively in the study group. It can be concluded that aerobic exercise has a positive effect on decreasing insulin resistance and hence decrease the incidence of diabetic complications.
    VL  - 5
    IS  - 5
    ER  - 

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Author Information
  • Department of Physical Therapy for Internal Medicine, Faculty of Physical Therapy, Cairo University, Cairo, Egypt

  • Department of Physical Therapy for Internal Medicine, Faculty of Physical Therapy, Cairo University, Cairo, Egypt

  • Department of Physical Therapy for Internal Medicine, Faculty of Physical Therapy, Cairo University, Cairo, Egypt

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