| Peer-Reviewed

Priapism due to Glyceryl Trinitrate in Adult Intensive Care Unit: A Case Report

Received: 6 January 2014     Published: 30 January 2014
Views:       Downloads:
Abstract

Priapism is a prolonged penile erection without sexual stimulation. Two forms of priapism are recognized: veno-occlusive or low-flow priapism and arterial or high-flow priapism. High-flow (arterial) priapism is usually the result of straddle injury. Treatment of high-flow priapism may be elective Low-flow priapism is usually related to sickle cell disease, haemoglobinopathies, neoplastic syndrome, psychotropic medication, anticoagulant therapy, or idiopathic causes. Low-flow priapism is a case of urologic emergency and priapism must be treated as emergency. A 52-year-old man was admitted to the neurology intensive care unit with the diagnosis of stroke. Glyceryl trinitrate was applied to the patient for the treatment of hypertension. In our case, Low-flow priapisms were completely due to glyceryl trinitrate therapy applied at the insensive care. We report a case of prolonged low-flow priapism induced by Glyceryl trinitrate. In literature, this is the first report of glyceryl trinitrate-associated priapism.

Published in Clinical Medicine Research (Volume 3, Issue 1)
DOI 10.11648/j.cmr.20140301.13
Page(s) 9-11
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Priapism, Glyceryl Trinitrate, Intensive Care Unit

References
[1] Eland IA, Van Der Lei J, Stricker BH, Sturkenboom MJ. Incidence of priapism in the general population. Urology 2001; 57: 970–972.
[2] Aktoz T, Tepeler A, Gundogdu EO, Ozkuvanci U, Muslumanoglu AY. Priapism in the newborn: management and review of literature. Andrologia 2011; 43: 65–67.
[3] Van Der Horst C, Stuebinger H, Seif C, Melchior D, F.J. Martinez-Portillo FJ, Juenemann KP. Priapism-etiology, pathophysiology and management. Int Braz J Urol. 2003; 29: 391-400.
[4] Bschleipfer TH, Hauck EW, Diemer TH, et al. Heparin-induced priapism. Int J Impot Res 2001; 13: 357–359.
[5] Willmot M, Ghadam A, Whysall B, Clarke W, Wardlaw J, Bath PMW. Transdermal Glyceryl Trinitrate Lowers Blood Pressure and Maintains Cerebral Blood Flow in Recent Stroke. Hypertension. 2006; 47: 1209-1215.
[6] Yuan J, Desouza R, Westney OL et al. Insights of priapism mechanism and rationale treatment for recurrent priapism. Asian J Androl 2008; 10: 88-101.
[7] Kogeorgos J, Alwis CD. Priapism and psychotropic medication. B J Psych 1986; 149: 241-243.
[8] Torun F, Yilmaz E, Gumus E. Priapism due to a Single Dose of Queti apine: A Case Report. Turk Psikiyatri Derg 2011; 22(3): 195-9.
[9] Brenner GM, Stevens CW. Pharmacology. 4th ed. Philadelphia: Elsevier Saunders, 2012, p 104
[10] Gruetter CA, Gruetter DY, Lyon JE, Kadowitz PJ, Ignarro LJ. Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin. J Pharmacol Exp Ther 1981; 219 (1): 181-186
[11] Hauri D, Spycher M, Bruhlmann W. Erection and priapism: a new physiopathological concept. Urol Int 1983; 38: 138–45.
[12] Golash A, Gray R, Ruttley MS, Jenkins BJ. Traumatic priapism: an unusual cycling injury. Br J Sports Med 2000; 34: 310–1.
[13] Harmon WJ, Nehra A. Priapism: diagnosis and management. Mayo Clin Proc 1997; 72: 350–5.
[14] Pranav NK, Sean OH. Priapism after androstenedione intake for athletic performance enhancement. Ann Emerg Med 2000; 35: 391–3.1. 15.
[15] Fowler JE, Koshy M, Strub M, et al. Priapism associated with the sickle cell hemoglobinopathies: prevalence, natural history and sequelae. J Urol 1991; 145: 65–8.
[16] O'Brien WM, O'Connor KP, Lynch JH. Priapism: current concepts. Ann Emerg Med 1989; 18: 980–3.
[17] Hekal IA, Meuleman EJH. Idiopathic Low-Flow Priapism in Prepuberty: A Case Report and a Review of Literature. Adv Urol 2008; doi:10.1155/2008/549861
[18] Mulhall JP, Honig SC. Priapism: Etiology and management. Acad Emerg Med 1996; 3: 810–6.1.21.
[19] Montague DK, Jarow J, Broderick GA, et al. American Urological Association guideline on the management of priapism. J Urol 2003; 170: 1318–1324.
[20] Stuttering Priapism: Insights into Pathogenesis and Management. Morrison BF, Burnett AL. Curr Urol Rep 2012 May 31.
[21] Tay YK, Spernat D, Rzetelski-West K, Appu S, Love C. Acute management of priapism in men. BJU Int 2012 Apr; 109 Suppl 3: 15-21.
Cite This Article
  • APA Style

    Erdogan Aglamis, Cemal Tasdemir, Mehmet Ozgur Yucel, Mehmet Sezai Ogras, Ercan Erdogan. (2014). Priapism due to Glyceryl Trinitrate in Adult Intensive Care Unit: A Case Report. Clinical Medicine Research, 3(1), 9-11. https://doi.org/10.11648/j.cmr.20140301.13

    Copy | Download

    ACS Style

    Erdogan Aglamis; Cemal Tasdemir; Mehmet Ozgur Yucel; Mehmet Sezai Ogras; Ercan Erdogan. Priapism due to Glyceryl Trinitrate in Adult Intensive Care Unit: A Case Report. Clin. Med. Res. 2014, 3(1), 9-11. doi: 10.11648/j.cmr.20140301.13

    Copy | Download

    AMA Style

    Erdogan Aglamis, Cemal Tasdemir, Mehmet Ozgur Yucel, Mehmet Sezai Ogras, Ercan Erdogan. Priapism due to Glyceryl Trinitrate in Adult Intensive Care Unit: A Case Report. Clin Med Res. 2014;3(1):9-11. doi: 10.11648/j.cmr.20140301.13

    Copy | Download

  • @article{10.11648/j.cmr.20140301.13,
      author = {Erdogan Aglamis and Cemal Tasdemir and Mehmet Ozgur Yucel and Mehmet Sezai Ogras and Ercan Erdogan},
      title = {Priapism due to Glyceryl Trinitrate in Adult Intensive Care Unit: A Case Report},
      journal = {Clinical Medicine Research},
      volume = {3},
      number = {1},
      pages = {9-11},
      doi = {10.11648/j.cmr.20140301.13},
      url = {https://doi.org/10.11648/j.cmr.20140301.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20140301.13},
      abstract = {Priapism is a prolonged penile erection without sexual stimulation. Two forms of priapism are recognized: veno-occlusive or low-flow priapism and arterial or high-flow priapism. High-flow (arterial) priapism is usually the result of straddle injury. Treatment of high-flow priapism may be elective Low-flow priapism is usually related to sickle cell disease, haemoglobinopathies, neoplastic syndrome, psychotropic medication, anticoagulant therapy, or idiopathic causes. Low-flow priapism is a case of urologic emergency and priapism must be treated as emergency. A 52-year-old man was admitted to the neurology intensive care unit with the diagnosis of stroke. Glyceryl trinitrate was applied to the patient for the treatment of hypertension. In our case, Low-flow priapisms were completely due to glyceryl trinitrate therapy applied at the insensive care. We report a case of prolonged low-flow priapism induced by Glyceryl trinitrate. In literature, this is the first report of glyceryl trinitrate-associated priapism.},
     year = {2014}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Priapism due to Glyceryl Trinitrate in Adult Intensive Care Unit: A Case Report
    AU  - Erdogan Aglamis
    AU  - Cemal Tasdemir
    AU  - Mehmet Ozgur Yucel
    AU  - Mehmet Sezai Ogras
    AU  - Ercan Erdogan
    Y1  - 2014/01/30
    PY  - 2014
    N1  - https://doi.org/10.11648/j.cmr.20140301.13
    DO  - 10.11648/j.cmr.20140301.13
    T2  - Clinical Medicine Research
    JF  - Clinical Medicine Research
    JO  - Clinical Medicine Research
    SP  - 9
    EP  - 11
    PB  - Science Publishing Group
    SN  - 2326-9057
    UR  - https://doi.org/10.11648/j.cmr.20140301.13
    AB  - Priapism is a prolonged penile erection without sexual stimulation. Two forms of priapism are recognized: veno-occlusive or low-flow priapism and arterial or high-flow priapism. High-flow (arterial) priapism is usually the result of straddle injury. Treatment of high-flow priapism may be elective Low-flow priapism is usually related to sickle cell disease, haemoglobinopathies, neoplastic syndrome, psychotropic medication, anticoagulant therapy, or idiopathic causes. Low-flow priapism is a case of urologic emergency and priapism must be treated as emergency. A 52-year-old man was admitted to the neurology intensive care unit with the diagnosis of stroke. Glyceryl trinitrate was applied to the patient for the treatment of hypertension. In our case, Low-flow priapisms were completely due to glyceryl trinitrate therapy applied at the insensive care. We report a case of prolonged low-flow priapism induced by Glyceryl trinitrate. In literature, this is the first report of glyceryl trinitrate-associated priapism.
    VL  - 3
    IS  - 1
    ER  - 

    Copy | Download

Author Information
  • Department of urology, Elazig Education and Research Hospital, Elazig, Turkey

  • Department of urology, Inonu University, Medical Faculty, Malatya, Turkey

  • Department of urology, Adiyaman Education and Research Hospital, Adiyaman, Turkey

  • Department of urology, Elazig Education and Research Hospital, Elazig, Turkey

  • Department of neurology, Elazig Education and Research Hospital, Elazig, Turkey

  • Sections