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Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention

Received: 28 August 2018     Accepted: 15 October 2018     Published: 5 November 2018
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Abstract

Background: Primary percutaneous coronary intervention (PCI) is the preferred method of ST-segment elevation acute myocardial infarction (STEMI) management but no-reflow phenomenon is one of its major complications that affects patient's outcome. Objective: Identification of possible clinical, angiographic and procedural predictors for no-reflow in patients with AMI after primary percutaneous coronary intervention (PCI). Methods: A total of hundred patients with AMI who had been treated by primary PCI at the National heart institute (NHI) and cardiology department, Menoufia University hospital were enrolled in this study, according to thrombolysis in myocardial infarction (TIMI) flow grade, patients were divided into a reflow group (TIMI 3) and a no-reflow group (TIMI ≤ 2). The clinical, angiographic and procedural data were compared between both groups. Discussion: Sixteen patients (16%) developed no-reflow phenomenon after primary PCI. Statistical analysis showed that time from onset to reperfusion, low initial TIMI flow grade, high thrombus burden, long lesion length and large reference luminal diameter were correlated with no-reflow (P < 0.05 for all) and were considered to be independent predictors of no-reflow. Conclusion: The occurrence of no-reflow after primary PCI for acute myocardial infarction can be predicted by certain clinical, angiographic and procedural features.

Published in Cardiology and Cardiovascular Research (Volume 2, Issue 3)
DOI 10.11648/j.ccr.20180203.15
Page(s) 68-74
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Acute Myocardial Infarction, Primary Percutaneous Coronary Intervention, No-Reflow, Coronary Thrombosis

References
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    Mohammed Ismail Ali, Wala Farid Abd El-Aziz, Adel Imam Abd El-Magid, Neveen Ibrahim Samy. (2018). Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention. Cardiology and Cardiovascular Research, 2(3), 68-74. https://doi.org/10.11648/j.ccr.20180203.15

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    ACS Style

    Mohammed Ismail Ali; Wala Farid Abd El-Aziz; Adel Imam Abd El-Magid; Neveen Ibrahim Samy. Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention. Cardiol. Cardiovasc. Res. 2018, 2(3), 68-74. doi: 10.11648/j.ccr.20180203.15

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    AMA Style

    Mohammed Ismail Ali, Wala Farid Abd El-Aziz, Adel Imam Abd El-Magid, Neveen Ibrahim Samy. Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention. Cardiol Cardiovasc Res. 2018;2(3):68-74. doi: 10.11648/j.ccr.20180203.15

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  • @article{10.11648/j.ccr.20180203.15,
      author = {Mohammed Ismail Ali and Wala Farid Abd El-Aziz and Adel Imam Abd El-Magid and Neveen Ibrahim Samy},
      title = {Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention},
      journal = {Cardiology and Cardiovascular Research},
      volume = {2},
      number = {3},
      pages = {68-74},
      doi = {10.11648/j.ccr.20180203.15},
      url = {https://doi.org/10.11648/j.ccr.20180203.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20180203.15},
      abstract = {Background: Primary percutaneous coronary intervention (PCI) is the preferred method of ST-segment elevation acute myocardial infarction (STEMI) management but no-reflow phenomenon is one of its major complications that affects patient's outcome. Objective: Identification of possible clinical, angiographic and procedural predictors for no-reflow in patients with AMI after primary percutaneous coronary intervention (PCI). Methods: A total of hundred patients with AMI who had been treated by primary PCI at the National heart institute (NHI) and cardiology department, Menoufia University hospital were enrolled in this study, according to thrombolysis in myocardial infarction (TIMI) flow grade, patients were divided into a reflow group (TIMI 3) and a no-reflow group (TIMI ≤ 2). The clinical, angiographic and procedural data were compared between both groups. Discussion: Sixteen patients (16%) developed no-reflow phenomenon after primary PCI. Statistical analysis showed that time from onset to reperfusion, low initial TIMI flow grade, high thrombus burden, long lesion length and large reference luminal diameter were correlated with no-reflow (P < 0.05 for all) and were considered to be independent predictors of no-reflow. Conclusion: The occurrence of no-reflow after primary PCI for acute myocardial infarction can be predicted by certain clinical, angiographic and procedural features.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention
    AU  - Mohammed Ismail Ali
    AU  - Wala Farid Abd El-Aziz
    AU  - Adel Imam Abd El-Magid
    AU  - Neveen Ibrahim Samy
    Y1  - 2018/11/05
    PY  - 2018
    N1  - https://doi.org/10.11648/j.ccr.20180203.15
    DO  - 10.11648/j.ccr.20180203.15
    T2  - Cardiology and Cardiovascular Research
    JF  - Cardiology and Cardiovascular Research
    JO  - Cardiology and Cardiovascular Research
    SP  - 68
    EP  - 74
    PB  - Science Publishing Group
    SN  - 2578-8914
    UR  - https://doi.org/10.11648/j.ccr.20180203.15
    AB  - Background: Primary percutaneous coronary intervention (PCI) is the preferred method of ST-segment elevation acute myocardial infarction (STEMI) management but no-reflow phenomenon is one of its major complications that affects patient's outcome. Objective: Identification of possible clinical, angiographic and procedural predictors for no-reflow in patients with AMI after primary percutaneous coronary intervention (PCI). Methods: A total of hundred patients with AMI who had been treated by primary PCI at the National heart institute (NHI) and cardiology department, Menoufia University hospital were enrolled in this study, according to thrombolysis in myocardial infarction (TIMI) flow grade, patients were divided into a reflow group (TIMI 3) and a no-reflow group (TIMI ≤ 2). The clinical, angiographic and procedural data were compared between both groups. Discussion: Sixteen patients (16%) developed no-reflow phenomenon after primary PCI. Statistical analysis showed that time from onset to reperfusion, low initial TIMI flow grade, high thrombus burden, long lesion length and large reference luminal diameter were correlated with no-reflow (P < 0.05 for all) and were considered to be independent predictors of no-reflow. Conclusion: The occurrence of no-reflow after primary PCI for acute myocardial infarction can be predicted by certain clinical, angiographic and procedural features.
    VL  - 2
    IS  - 3
    ER  - 

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Author Information
  • Cardiology Department, 6 October Hospital, General Health Insurance, Giza, Egypt

  • Cardiology Department, Menoufia University, Menoufia, Egypt

  • Cardiology Department, National Heart Institute, Giza, Egypt

  • Cardiology Department, Menoufia University, Menoufia, Egypt

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