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Contrast-Induced Nephropathy Among Patients Undergoing Cardiac Catheterization

Received: 25 August 2018     Accepted: 20 September 2018     Published: 17 October 2018
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Abstract

Contrast-induced nephropathy is an important complication after cardiac catheterization, and is associated with accelerated renal disease, increased costs, mortality rate, need for dialysis and prolonged hospital stay. This study aim is to find its incidence and risk factors. It is a cross-sectional study on 160 patients admitted for diagnostic or therapeutic percutaneous coronary intervention in Basra Cardiac Center, from March to September 2016. Data collected were a complete history, examination, blood pressure, Echo study, fasting blood sugar, lipid profile, blood urea, serum creatinine and estimated glomerular filtration rate, the type and duration of procedure, volume of contrast, and after 48 hours renal function tests were repeated. Contrast-induced nephropathy has developed in 7 (8.3%) men and 5 (6.6%) women; 11 (10.8%) from 102 patients with dyslipidemia (P = 0.03); 8 (22.2%) from 36 with preexisting renal impairment (P = 0.01); 11 (10.9%) from 101 with hypertension (P = 0.02); 9 (13.6%) from 66 diabetic (P = 0.016); 9 (17.3%) from 52 smoker (P = 0.002); 4 (23.5%) from 17 alcohol drinkers (P = 0.026); 11 (11.2%) from 98 with ischemic heart disease (P = 0.02); and 9 (25.7%) from 35 with heart failure (P = <0.001). Also found in 1 (1.6%) from 64 diagnostic procedures; 11 (11.5%) from 96 therapeutic procedures (P = 0.016); 5 (3.7%) from 135 patients received < 300 ml of contrast; and 7 (28%) from 25 received ≥ 300 ml (P = 0.001). In conclusion contrast-induced nephropathy is aggravated by increasing age, diabetes mellitus, heart failure, ischemic heart disease, renal impairment, hypertension, dyslipidemia, smoking and alcohol use. The type of procedure (therapeutic vs. diagnostic), and large volume of contrast agent are important risk factors. Gender had no significant effect.

Published in Cardiology and Cardiovascular Research (Volume 2, Issue 3)
DOI 10.11648/j.ccr.20180203.12
Page(s) 55-60
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Cardiac Catheterization, Contrast Media, Acute Kidney Injury

References
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    Safauldeen Ahmed Alhajim, Ahmed Sami Jebur. (2018). Contrast-Induced Nephropathy Among Patients Undergoing Cardiac Catheterization. Cardiology and Cardiovascular Research, 2(3), 55-60. https://doi.org/10.11648/j.ccr.20180203.12

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    Safauldeen Ahmed Alhajim; Ahmed Sami Jebur. Contrast-Induced Nephropathy Among Patients Undergoing Cardiac Catheterization. Cardiol. Cardiovasc. Res. 2018, 2(3), 55-60. doi: 10.11648/j.ccr.20180203.12

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    AMA Style

    Safauldeen Ahmed Alhajim, Ahmed Sami Jebur. Contrast-Induced Nephropathy Among Patients Undergoing Cardiac Catheterization. Cardiol Cardiovasc Res. 2018;2(3):55-60. doi: 10.11648/j.ccr.20180203.12

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  • @article{10.11648/j.ccr.20180203.12,
      author = {Safauldeen Ahmed Alhajim and Ahmed Sami Jebur},
      title = {Contrast-Induced Nephropathy Among Patients Undergoing Cardiac Catheterization},
      journal = {Cardiology and Cardiovascular Research},
      volume = {2},
      number = {3},
      pages = {55-60},
      doi = {10.11648/j.ccr.20180203.12},
      url = {https://doi.org/10.11648/j.ccr.20180203.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20180203.12},
      abstract = {Contrast-induced nephropathy is an important complication after cardiac catheterization, and is associated with accelerated renal disease, increased costs, mortality rate, need for dialysis and prolonged hospital stay. This study aim is to find its incidence and risk factors. It is a cross-sectional study on 160 patients admitted for diagnostic or therapeutic percutaneous coronary intervention in Basra Cardiac Center, from March to September 2016. Data collected were a complete history, examination, blood pressure, Echo study, fasting blood sugar, lipid profile, blood urea, serum creatinine and estimated glomerular filtration rate, the type and duration of procedure, volume of contrast, and after 48 hours renal function tests were repeated. Contrast-induced nephropathy has developed in 7 (8.3%) men and 5 (6.6%) women; 11 (10.8%) from 102 patients with dyslipidemia (P = 0.03); 8 (22.2%) from 36 with preexisting renal impairment (P = 0.01); 11 (10.9%) from 101 with hypertension (P = 0.02); 9 (13.6%) from 66 diabetic (P = 0.016); 9 (17.3%) from 52 smoker (P = 0.002); 4 (23.5%) from 17 alcohol drinkers (P = 0.026); 11 (11.2%) from 98 with ischemic heart disease (P = 0.02); and 9 (25.7%) from 35 with heart failure (P = <0.001). Also found in 1 (1.6%) from 64 diagnostic procedures; 11 (11.5%) from 96 therapeutic procedures (P = 0.016); 5 (3.7%) from 135 patients received < 300 ml of contrast; and 7 (28%) from 25 received ≥ 300 ml (P = 0.001). In conclusion contrast-induced nephropathy is aggravated by increasing age, diabetes mellitus, heart failure, ischemic heart disease, renal impairment, hypertension, dyslipidemia, smoking and alcohol use. The type of procedure (therapeutic vs. diagnostic), and large volume of contrast agent are important risk factors. Gender had no significant effect.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Contrast-Induced Nephropathy Among Patients Undergoing Cardiac Catheterization
    AU  - Safauldeen Ahmed Alhajim
    AU  - Ahmed Sami Jebur
    Y1  - 2018/10/17
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    T2  - Cardiology and Cardiovascular Research
    JF  - Cardiology and Cardiovascular Research
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    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.ccr.20180203.12
    AB  - Contrast-induced nephropathy is an important complication after cardiac catheterization, and is associated with accelerated renal disease, increased costs, mortality rate, need for dialysis and prolonged hospital stay. This study aim is to find its incidence and risk factors. It is a cross-sectional study on 160 patients admitted for diagnostic or therapeutic percutaneous coronary intervention in Basra Cardiac Center, from March to September 2016. Data collected were a complete history, examination, blood pressure, Echo study, fasting blood sugar, lipid profile, blood urea, serum creatinine and estimated glomerular filtration rate, the type and duration of procedure, volume of contrast, and after 48 hours renal function tests were repeated. Contrast-induced nephropathy has developed in 7 (8.3%) men and 5 (6.6%) women; 11 (10.8%) from 102 patients with dyslipidemia (P = 0.03); 8 (22.2%) from 36 with preexisting renal impairment (P = 0.01); 11 (10.9%) from 101 with hypertension (P = 0.02); 9 (13.6%) from 66 diabetic (P = 0.016); 9 (17.3%) from 52 smoker (P = 0.002); 4 (23.5%) from 17 alcohol drinkers (P = 0.026); 11 (11.2%) from 98 with ischemic heart disease (P = 0.02); and 9 (25.7%) from 35 with heart failure (P = <0.001). Also found in 1 (1.6%) from 64 diagnostic procedures; 11 (11.5%) from 96 therapeutic procedures (P = 0.016); 5 (3.7%) from 135 patients received < 300 ml of contrast; and 7 (28%) from 25 received ≥ 300 ml (P = 0.001). In conclusion contrast-induced nephropathy is aggravated by increasing age, diabetes mellitus, heart failure, ischemic heart disease, renal impairment, hypertension, dyslipidemia, smoking and alcohol use. The type of procedure (therapeutic vs. diagnostic), and large volume of contrast agent are important risk factors. Gender had no significant effect.
    VL  - 2
    IS  - 3
    ER  - 

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Author Information
  • Department of Medicine, University of Basrah, Basrah, Iraq

  • Department of Medicine, Shifa Hospital, Basrah, Iraq

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