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The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion

Received: 9 July 2017     Accepted: 24 August 2017     Published: 21 September 2017
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Abstract

The most susceptible to vascular dementia persons with lesions of small cerebral vessels. This variant of the pathology is characterized by subacute course and pathologic basis is diffuse changes in the white matter of the cerebral hemispheres and lacunar infarctions, in most cases - multiple. That is why the appearance of lacunar infarcts associated with step-progression of the disease. However, not in all cases, there is a significant cognitive defect even in a lacunary condition. The aim of the study was to identify cognitive impairment in patients with lacunar stroke, depending on hemispheric lateralization of the lesion. We observed and surveyed 70 patients (mean age 60.2 + 6.3) suffered the lacunar stroke with hemispheric lateralization of the lesion. In this work, we used the Mini-Mental State Examination (MMSE) and Montreal scale assessment of cognitive functions (MoCA), the Saint Louis University Mental Status Examination (SLUMS), which have been developed as a tool to identify and assess the severity of cognitive functions in general practice. Comparative analysis of cognitive impairment on the stage of the disease in the control group showed that in general, patients suffered lacunar stroke level of violations was significantly higher than the control group (p≤0.01). Cognitive function in right lacunar stroke corresponded moderate cognitive impairment and the restoration of the neurological defect in the dynamics were less expressed and are not complete. Cognitive impairment in the left hemisphere lacunar stroke had a mild degree of cognitive impairment and restoration of disturbed functions is progressing at a faster pace, about what speak reliable indicators of the late recovery period (p≤0.05). The differences in cognitive disorders at different focus lateralization underlie the clinical features and determine the nature and pace of the recovery of lost functions. Mild cognitive impairment in the left-hand lacunar stroke is a favorable prognostic factor in terms of the recovery of lost functions.

Published in American Journal of Psychiatry and Neuroscience (Volume 5, Issue 5)
DOI 10.11648/j.ajpn.20170505.12
Page(s) 56-59
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Lacunar Stroke, Vascular Dementia, Cognitive Impairment

References
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[3] Parfenov V. A. Dementia // Clinical Gerontology. 2016. — Vol. 12, No. 11. -P. 3-10.
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[10] Debette S., Bombois S., Bruandet A. et al. Subcortical hyperintensities are associated with cognitive decline in patients with mild cognitive impairment // Stroke. 2007. № 38. P. 2595-2597.
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[12] Giovannetti, T. Personal Interview. 16 October 2009.
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[16] Hajek VE, Gagnon S, Ruderman JE. Cognitive and functional assessments of stroke patients: an analysis of their reaction. Arch Phys Med Rehabil 1997; 7: 1331-7.
[17] Meier MJ, Ettinger MC, ARthur L. Recovery of neuropsyhological functioning after cerebrovascular infarction. Neuropsychology and cognition. NATO Advanced Study Series 1982; 552-64.
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  • APA Style

    Bekhzod Abdullaev, Elvina Giyazitdinova, Yulduz Musaeva. (2017). The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion. American Journal of Psychiatry and Neuroscience, 5(5), 56-59. https://doi.org/10.11648/j.ajpn.20170505.12

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    ACS Style

    Bekhzod Abdullaev; Elvina Giyazitdinova; Yulduz Musaeva. The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion. Am. J. Psychiatry Neurosci. 2017, 5(5), 56-59. doi: 10.11648/j.ajpn.20170505.12

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    AMA Style

    Bekhzod Abdullaev, Elvina Giyazitdinova, Yulduz Musaeva. The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion. Am J Psychiatry Neurosci. 2017;5(5):56-59. doi: 10.11648/j.ajpn.20170505.12

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  • @article{10.11648/j.ajpn.20170505.12,
      author = {Bekhzod Abdullaev and Elvina Giyazitdinova and Yulduz Musaeva},
      title = {The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion},
      journal = {American Journal of Psychiatry and Neuroscience},
      volume = {5},
      number = {5},
      pages = {56-59},
      doi = {10.11648/j.ajpn.20170505.12},
      url = {https://doi.org/10.11648/j.ajpn.20170505.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajpn.20170505.12},
      abstract = {The most susceptible to vascular dementia persons with lesions of small cerebral vessels. This variant of the pathology is characterized by subacute course and pathologic basis is diffuse changes in the white matter of the cerebral hemispheres and lacunar infarctions, in most cases - multiple. That is why the appearance of lacunar infarcts associated with step-progression of the disease. However, not in all cases, there is a significant cognitive defect even in a lacunary condition. The aim of the study was to identify cognitive impairment in patients with lacunar stroke, depending on hemispheric lateralization of the lesion. We observed and surveyed 70 patients (mean age 60.2 + 6.3) suffered the lacunar stroke with hemispheric lateralization of the lesion. In this work, we used the Mini-Mental State Examination (MMSE) and Montreal scale assessment of cognitive functions (MoCA), the Saint Louis University Mental Status Examination (SLUMS), which have been developed as a tool to identify and assess the severity of cognitive functions in general practice. Comparative analysis of cognitive impairment on the stage of the disease in the control group showed that in general, patients suffered lacunar stroke level of violations was significantly higher than the control group (p≤0.01). Cognitive function in right lacunar stroke corresponded moderate cognitive impairment and the restoration of the neurological defect in the dynamics were less expressed and are not complete. Cognitive impairment in the left hemisphere lacunar stroke had a mild degree of cognitive impairment and restoration of disturbed functions is progressing at a faster pace, about what speak reliable indicators of the late recovery period (p≤0.05). The differences in cognitive disorders at different focus lateralization underlie the clinical features and determine the nature and pace of the recovery of lost functions. Mild cognitive impairment in the left-hand lacunar stroke is a favorable prognostic factor in terms of the recovery of lost functions.},
     year = {2017}
    }
    

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    T1  - The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion
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    AU  - Elvina Giyazitdinova
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    AB  - The most susceptible to vascular dementia persons with lesions of small cerebral vessels. This variant of the pathology is characterized by subacute course and pathologic basis is diffuse changes in the white matter of the cerebral hemispheres and lacunar infarctions, in most cases - multiple. That is why the appearance of lacunar infarcts associated with step-progression of the disease. However, not in all cases, there is a significant cognitive defect even in a lacunary condition. The aim of the study was to identify cognitive impairment in patients with lacunar stroke, depending on hemispheric lateralization of the lesion. We observed and surveyed 70 patients (mean age 60.2 + 6.3) suffered the lacunar stroke with hemispheric lateralization of the lesion. In this work, we used the Mini-Mental State Examination (MMSE) and Montreal scale assessment of cognitive functions (MoCA), the Saint Louis University Mental Status Examination (SLUMS), which have been developed as a tool to identify and assess the severity of cognitive functions in general practice. Comparative analysis of cognitive impairment on the stage of the disease in the control group showed that in general, patients suffered lacunar stroke level of violations was significantly higher than the control group (p≤0.01). Cognitive function in right lacunar stroke corresponded moderate cognitive impairment and the restoration of the neurological defect in the dynamics were less expressed and are not complete. Cognitive impairment in the left hemisphere lacunar stroke had a mild degree of cognitive impairment and restoration of disturbed functions is progressing at a faster pace, about what speak reliable indicators of the late recovery period (p≤0.05). The differences in cognitive disorders at different focus lateralization underlie the clinical features and determine the nature and pace of the recovery of lost functions. Mild cognitive impairment in the left-hand lacunar stroke is a favorable prognostic factor in terms of the recovery of lost functions.
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Author Information
  • Department of Neurology, Tashkent Medical Academy, Tashkent, Uzbekistan

  • Department of Neurology, Tashkent Medical Academy, Tashkent, Uzbekistan

  • Department of Neurology, Tashkent Medical Academy, Tashkent, Uzbekistan

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