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Often a Sick Child from the Perspective of a Pediatrican/Clinical Immunologist

Received: 22 March 2021     Accepted: 6 April 2021     Published: 13 April 2021
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Abstract

The author considers the term "often a sick child" and discusses this topic in relation to the gradually maturing immune system. He points out the specifics of different age periods and tries to prove that the not always higher frequency of diseases (especially the most common ones - respiratory tract infections) must have a cause in the immune system. Above all, it is necessary to distinguish between primary-congenital immune disorders, which often require lifelong specialized care, from secondary-acquired disorders, for which it is most important to identify the cause of such a disorder and try to eliminate it. An irreplaceable role in the diagnosis and care of often ill children is played by general practitioners caring for children and adolescents, who know the environment in which the child develops and have the possibility of basic immunological examination to identify more serious immune disorders.

Published in American Journal of Pediatrics (Volume 7, Issue 2)
DOI 10.11648/j.ajp.20210702.14
Page(s) 57-61
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Often Sick Child, Immune Disorder, Congenital Immunodeficiency, Acquired Immunodeficiency

References
[1] Toivonen L, Karppinen S, Schuez-Havupalo L, Teros-Jaakkola T, Vuononvirta J, Mertsola J, He Q, Waris M, Peltola V: The burden of recurrent respiratory infections in children: A prospective cohort study. Pediatr Infect Dis J. 2016 December; 35 (12): e362-e369.
[2] Jeseňák M, Rennerová Z, Bánovčin P a kol.: Recidivujúce infekcie dýchacích ciest a imunomodulácia u detí.(Recurrent respiratory tract infections and immunomodulation in children.) 2012, Eds. Aeskulap, Mladá fronta (Czech rep. in Czech language)).
[3] De Benedictis FM, Bush A.: Repeated lower respiratory tract infections in children. BMJ. 2018 July 12; 362: k2698. doi: 10.1136/bmj.k2698.PMID: 30002015.
[4] Pasternak G, Lewandowicz-Uszyńska A, Królak-Olejnik B. [Recurrent respiratory infections in children]. Pol Merkur Lekarski. 2020 Aug 22; 49 (286): 260-266. PMID: 32827422 Review. Polish.
[5] S. Jolles, S. Sánchez-Ramón,. Quinti: Screening protocols for monitoring the respiratory status of primary immunodeficiency disease: findings from the European Working Group on Survey and Subclinical Infections. Respir Res. 2018; 19: 219.
[6] Pere Soler-Palacín, Javier de Gracia, Luis Ignacio González-Granado, Carlos Martín, Carlos Rodríguez-Gallego, Silvia Sánchez-Ramón, and pulmonary id-group: Primary diseases of immunodeficiency in lung diseases: warning signs, diagnosis and treatment. Respir Res. 2018 November, 12; 19 (1): d219. doi: 10.1186/s12931-018-0923-8. PMID: 30419907.
[7] Bystroň J.: Nemoci z nachlazení z pohledu imunologa. Je potřeba ovlivňovat imunitu v dětském věku? (Cold diseases from the perspective of an immunologist. Is it necessary to influence immunity in childhood?) Pediatrie pro praxi (Pediatrics for practice). 2019, roč. 20, č. 1, s. 49-54. ISSN: 1213-0494; 1803-5264 (Czech rep.-czech language).
[8] Esposito S, Soto-Martinez ME, Feleszko W, Jones MH, Shen KL, Schaad UB. Non-specific immunomodulators for recurrent respiratory infections, wheezing and asthma in children: a systematic review of mechanistic and clinical evidence. Curr Opin Allergy Clin Immunol. 2018 June; 18 (3): 198-209. doi: 10.1097.
[9] Esposito S, Bianchini S, Bosis S, Tagliabue C, Coro I, Argentiero A, Principi N. A randomized, placebo-controlled, double-blind phase IV study to assess the efficacy and safety of OM-85 in children with recurrent respiratory infections. J Transl Med. 2019 Aug 23; 17 (1): 284. doi: 10.1186/s12967-019-2040-y. PMID: 31443716.
[10] Yin J, Xu B, Zeng X, Shen K. Broncho-Vaxom in pediatric recurrent respiratory infections: A systematic review and meta-analysis. Int Immunopharmacol. January 2018; 54: 198-209. doi: 10.1016/j.intimp.2017.10.032. Epub 2017 October 16.PMID: 29154122.
[11] Tarantino V, Savaia V, D'Agostino R, Silvestri M, Passali FM, Di Girolamo S, Ciprandi G. Bacteriotherapy in children with recurrent upper respiratory tract infections. Eur Rev Med Pharmacol Sci. 2019 March; 23 (1 Suppl): 39-43. doi: 10.26355/eurrev_201903_17347. PMID: 30920639.
[12] Hawke K, van Driel ML, Buffington BJ, McGuireTM, Homeopathic Remedies for the Prevention and Treatment of Acute Respiratory Infections in Children. Cochrane Syst. 2018 September 9; 9 (9): CD005974. doi: 10.1002/14651858.CD005974.pub5.PMID: 30196554.
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  • APA Style

    Jaromir Bystron. (2021). Often a Sick Child from the Perspective of a Pediatrican/Clinical Immunologist. American Journal of Pediatrics, 7(2), 57-61. https://doi.org/10.11648/j.ajp.20210702.14

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    ACS Style

    Jaromir Bystron. Often a Sick Child from the Perspective of a Pediatrican/Clinical Immunologist. Am. J. Pediatr. 2021, 7(2), 57-61. doi: 10.11648/j.ajp.20210702.14

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    AMA Style

    Jaromir Bystron. Often a Sick Child from the Perspective of a Pediatrican/Clinical Immunologist. Am J Pediatr. 2021;7(2):57-61. doi: 10.11648/j.ajp.20210702.14

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  • @article{10.11648/j.ajp.20210702.14,
      author = {Jaromir Bystron},
      title = {Often a Sick Child from the Perspective of a Pediatrican/Clinical Immunologist},
      journal = {American Journal of Pediatrics},
      volume = {7},
      number = {2},
      pages = {57-61},
      doi = {10.11648/j.ajp.20210702.14},
      url = {https://doi.org/10.11648/j.ajp.20210702.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20210702.14},
      abstract = {The author considers the term "often a sick child" and discusses this topic in relation to the gradually maturing immune system. He points out the specifics of different age periods and tries to prove that the not always higher frequency of diseases (especially the most common ones - respiratory tract infections) must have a cause in the immune system. Above all, it is necessary to distinguish between primary-congenital immune disorders, which often require lifelong specialized care, from secondary-acquired disorders, for which it is most important to identify the cause of such a disorder and try to eliminate it. An irreplaceable role in the diagnosis and care of often ill children is played by general practitioners caring for children and adolescents, who know the environment in which the child develops and have the possibility of basic immunological examination to identify more serious immune disorders.},
     year = {2021}
    }
    

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    AB  - The author considers the term "often a sick child" and discusses this topic in relation to the gradually maturing immune system. He points out the specifics of different age periods and tries to prove that the not always higher frequency of diseases (especially the most common ones - respiratory tract infections) must have a cause in the immune system. Above all, it is necessary to distinguish between primary-congenital immune disorders, which often require lifelong specialized care, from secondary-acquired disorders, for which it is most important to identify the cause of such a disorder and try to eliminate it. An irreplaceable role in the diagnosis and care of often ill children is played by general practitioners caring for children and adolescents, who know the environment in which the child develops and have the possibility of basic immunological examination to identify more serious immune disorders.
    VL  - 7
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Author Information
  • Department of Allergy and Clinical Immunology, University Hospital, Ostrava, Czech Rep

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