Communication | | Peer-Reviewed

Deteriorating Patient: A Necessary Definition for Cardiac Arrest Prevention

Received: 30 June 2025     Accepted: 5 August 2025     Published: 8 September 2025
Views:       Downloads:
Abstract

Backgraund: Clinical deterioration not promptly recognized can result in increased patient morbidity and mortality. Early warning of cardiac arrest is a criterion commonly used in nursing staff's daily practice to identify patient deterioration. However, it is not always clear what a deteriorating patient means. Objetives: Provide an evidence-based approach to creating the definition of deteriorating patient Contextualize the definition of a deteriorating patient. Methods: A documentary review study was conducted through a bibliographic search of the databases to address the term deteriorating patient. Information about deteriorating patients was collected. Conclusion: As a result, valuable data were obtained to conceptualize the term deteriorated patient in nursing practice.

Published in American Journal of Nursing and Health Sciences (Volume 6, Issue 3)
DOI 10.11648/j.ajnhs.20250603.14
Page(s) 55-58
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Nursing, Clinical Deterioration, Cardiac Arrest, Deteriorating Patient

1. Introduction
Early warning of cardiac arrest is a criterion commonly used in nursing staff's daily practice to identify patient deterioration. However, it is not always clear what a deteriorating patient means.
Little is known about the role of nurses or midwives in out-of-hospital settings and their recognition, response, and communication of information about patient deterioration. The complex and subtle nature of mild deterioration makes it difficult to define and subsequently assess the role and impact of nurses in these settings .
2. Clinical Deterioration
Clinical deterioration in patients hospitalized outside of intensive care units (ICUs) is a significant problem in healthcare systems. Studies show that more than 15% of patients hospitalized in general wards are at medium risk and 17% are at high risk of clinical instability . Late detection of this deterioration is associated with higher mortality rates, and it is of particular concern that patients who worsen in general wards before being transferred to the ICU have a 50% mortality rate .
In recent years, care for patients with deteriorating conditions has improved thanks to technological advances. The aging of the global population means that patients often present with more complex comorbidities, and therefore, their health status deteriorates from an increasingly complex baseline situation. Nursing staff constitute the largest segment of the healthcare workforce and often have frequent contact with patients, making them more likely to be able to detect deterioration and respond accordingly.
Much is known about various aspects of clinical deterioration, especially with regard to detection and treatment; however, little is known about how nursing staff experience clinical deterioration in their patients.
Clinical deterioration is the critical progression of a disease, often measured by a set of clinical parameters, which triggers the rapid response hospital team. . Clinical deterioration is a key factor in mortality in hospitalized patients and its recognition is often supported by contextual factors and variations in practice.
The variation in the uniformity of the concept of clinical deterioration causes a gap in knowledge and requires clarification of this phenomenon for nursing research and practice. Relevance to clinical practice Identifying and intervening in clinical deterioration plays a vital role in the hospital setting, demonstrated by the dynamic nature of a patient’s condition during hospitalization. It is anticipated that this conceptual analysis on clinical deterioration will contribute to greater identification of clinically modifiable risk factors and complementary interventions to prevent clinical deterioration in the hospital setting.
Defining attributes include dynamic state, decompensation and objective and subjective determination. Antecedents identified include clinical state, susceptibility, pathogenesis and adverse event. Increased mortality, resuscitation, implementation of higher level of care and prolonged hospital admission were the consequences identified. Defining attributes, antecedents and consequences identified led to an operational definition of clinical deterioration as a dynamic state experienced by a patient compromising hemodynamic stability, marked by physiological decompensation accompanied by subjective or objective findings.
2.1. Vital Sings
Vital sign observations are often done more frequently than necessary from a bald assessment of the patient’s risk, and we show that a maximum threshold of risk could theoretically be achieved with less resource.
The paper Briggs et al, safer and more efficient vital signs monitoring protocols to identify the deteriorating patients are 'observed' regularly by nursing staff so that deterioration can be spotted early .
They stated that vital sign trends increased detection of clinical deterioration. Critical appraisal was performed using evaluation tools. The studies had moderate risk of bias, and a low certainty of evidence. Additionally, four studies examining trends in early warning scores, otherwise eligible for inclusion, were evaluated.
2.2. Critical Value
A critical value is a laboratory result that reflects a pathological state that may endanger the patient's life unless appropriate measures are taken promptly.
In the not-too-distant future, we will be able to rely on portable imaging tools and studies for assessment, prediction, and planning, portable intubation devices with wireless connection to smartphones, and laptop computers and displays that feed databases and improve our management algorithms. Artificial Intelligence can generate analysis and predict events and risks; however, clinical judgment in decision-making will remain essential.
Rapid response to extremely abnormal test results helps prevent adverse adult and pediatric patient outcomes.
2.3. Rapid Response Team
In a study conducted by Meneguin et al., they suggest that it can also contribute to the development of other research, advancing the construction of knowledge about the role of nursing in rapid response teams, with data that can highlight the importance of the actions carried out by this professional to hospitalized patients with signs of clinical deterioration and who need immediate intervention.
Nursing care in situations of Cardiorespiratory Arrest (CPR) plays a crucial role, since time is a determining factor for the patient's survival. [In the study described by Valero on the evolution of CPR in hospitalized patients, it does not usually occur suddenly, but rather as a result of a gradual deterioration of these mostly multi-pathological patients.
Future research should focus on evaluating the impact of strategies on the quality of care, especially in critical areas such as emergency departments, intensive care units, and primary care. This will allow progress toward a more reflective, decisive, and empowered nursing system, capable of robustly addressing current and future challenges in health care.
After investigating the definition of the term deteriorated patient, as a valuable concept for usefulness in care, with essential meanings for the whole, and not finding a clear definition in Spanish, not being so in the Anglo-Saxon world where several articles refer to that term , it has been possible to define a construct of deteriorated patient.
3. Methodology
In the doctoral program: Nursing Sciences of the University of Medical Sciences of Villa Clara, Cuba under the coverage of a line of doctoral research entitled: Nursing as a science of care in the promotion, prevention, cure and rehabilitation of health; and the topic "design of the early warning system in Nursing for the prevention of cardiac arrest", from the search and review of the bibliography and the proposal of an early warning system in Nursing, it has been raised because a conceptualization that supports the term deteriorating patient was not found in the reviewed literature.
A documentary review study was conducted through a bibliographic search of the databases to address the term deteriorating patient. Information about deteriorating patients was collected.
Search results
Initial searches yielded 909 studies (after removal of duplicates), of which 92 were selected for full-text review. Fifteen papers met eligibility criteria and an additional five were added through citation tracking and other sources before undergoing data extraction.
The methodological quality of the studies was not formally assessed in line with the framework of scoping reviews.
Of the 54 articles excluded during full-text assessment, 38 did not provide sufficient detail.
Key characteristics of primary research studies and review articles are detailed separately below.
Included Eligibility Screening Identification Studies identified from reference lists .
4. Result
As a result, valuable data were obtained to conceptualize the term deteriorating patient.
The above leads us to reflect on the term "deteriorating patient," which is frequently used by nursing as well as other health disciplines.
The information gathered allowed the author to carry out an analysis, debate and delimitation on proposing, adapting and contextualizing the definition of a deteriorated patient from the different dimensions and taking clinical deterioration as a premise: defining the term Deteriorated Patient as an individual whose medical condition worsens or is in decline through the detection of vital signs, signs and symptoms of worsening, critical values and/or consensus on decision-making to prevent worsening of the health status.
5. Conclusion
Deteriorating patient is a key contributor to inpatient mortality, and its recognition is often underpinned by contextual factors and practice variances. Variation in the uniformity of the concept of deteriorating patient causes a gap in knowledge and necessitated definition of this concept for nursing practice. Due to its importance and relevance, it is necessary to address this topic for future research and grow the level of professional competence and performance. Taking into account that continuous updating provides better professional preparation and better care.
Abbreviations

ICU

Intensive Care Unit

CPR

Cardiorespiratory Arrest

Author Contributions
Hector Roche Molina is the sole author. The author read and approved the final manuscript.
Conflicts of Interest
The author declares no conflicts of interest.
References
[1] Gondim ÉS, Gomes EB, Matos JHFd, Pinto SdL, Oliveira CJd, Alencar AMPG. Technologies used by nursing to predict clinical deterioration in hospitalized adults: a scoping review. Rev bras enferm. 2022; 75(5): e20210570-e.
[2] Albutt AK, O'Hara JK, Conner MT, Fletcher SJ, Lawton RJ. Is there a role for patients and their relatives in escalating clinical deterioration in hospital? A systematic review. Health expectations: an international journal of public participation in health care and health policy. 2017; 20(5): 818-25.
[3] Considine J, Fry M, Curtis K, Shaban RZ. Systems for recognition and response to deteriorating emergency department patients: a scoping review. Scandinavian journal of trauma, resuscitation and emergency medicine. 2021; 29(1): 69.
[4] Demisse L, Baru A, Alemayehu M, Sultan M. Prehospital characteristics of COVID-19 patients transported by emergency medical service and the predictors of a prehospital sudden deterioration in Addis Ababa, Ethiopia. ResearchSquare. 2022.
[5] Deterioro Clínico. Available from:
[6] Lavoie P, Pepin J, Alderson M. Defining patient deterioration through acute care and intensive care nurses' perspectives. Nurs Crit Care. 2016 2016/00 [cited 20141002; 21(2):[68-77 pp.]. Available from:
[7] Zuin M, Rigatelli G, Bongarzoni A, Enea I, Bilato C, Zonzin P, et al. Mean arterial pressure predicts 48 h clinical deterioration in intermediate-high risk patients with acute pulmonary embolism. Eur Heart J Acute Cardiovasc Care. 2023; 12(2): 80-6.
[8] Zinkan JL, Rutledge C, Norwood C, Wise KM, Gaither S, Cameron B, et al. Nurse Vigilance: A Three-Part Simulation Course to Decrease Cardiopulmonary Arrests Outside Intensive Care Units. J Nurses Prof Dev. 2019; 35(4): E1-E8.
[9] Zhao Y-Y, Liu C, Zeng Y-Q, Zhou A-Y, Duan J-X, Cheng W, et al. Modified and simplified clinically important deterioration: multidimensional indices of short-term disease trajectory to predict future exacerbations in patients with chronic obstructive pulmonary disease. Ther Adv Respir Dis. 2020; 14: 1753466620977376-.
[10] Zhang J, Lu S, Wang X, Jia X, Li J, Lei H, et al. Do underlying cardiovascular diseases have any impact on hospitalised patients with COVID-19? Heart. 2020; 106(15): 1148-53.
[11] Yitao Z, Mu C, Ling Z, Shiyao C, Jiaojie X, Zhichong C, et al. Predictors of clinical deterioration in non-severe patients with COVID-19: a retrospective cohort study. Curr Med Res Opin. 2021; 37(3): 385-91.
[12] Augutis W, Flenady T, Le Lagadec D, Jefford E. How do nurses use early warning system vital signs observation charts in rural, remote and regional health care facilities: A scoping review. Aust J Rural Health. 2023; 31(3): 385-94.
[13] Padilla RM, Mayo AM. Clinical deterioration: A concept analysis. Journal of clinical nursing. 2018; 27(7-8): 1360-8.
[14] Briggs J, Kostakis I, Meredith P, Darbyshire J, Gerry S, Watkinson P, et al. Safer and more efficient vital signs monitoring to identify the deteriorating patient: An observational study towards deriving evidence-based protocols for patient surveillance on the general hospital ward. Health and Social Care Delivery Research. 2024; 12(6).
[15] Briggs J, Kostakis I, Meredith P, Dall'ora C, Darbyshire J, Gerry S, et al. Safer and more efficient vital signs monitoring protocols to identify the deteriorating patients in the general hospital ward: an observational study. Health Soc Care Deliv Res. 2024; 12(6): 1-143.
[16] Brekke IJ, Puntervoll LH, Pedersen PB, Kellett J, Brabrand M. The value of vital sign trends in predicting and monitoring clinical deterioration: A systematic review. PLoS One. 2019; 14(1): e0210875-e.
[17] Chen SL, Feng HY, Xu H, Huang SS, Sun JF, Zhou L, et al. Patterns of Deterioration in Moderate Patients With COVID-19 From Jan 2020 to Mar 2020: A Multi-Center, Retrospective Cohort Study in China. Frontiers in medicine. 2020; 7: 567296.
[18] Martínez-de los Santos CA, Escudero-Guitérrez F, Hernández-Morales F, Garza-Santos A, Reyes-Gutiérrez A, Cantú-Flores F. Inteligencia Artificial y la anestesia del futuro. Rev Chil Anest. 2024; 53(3): 206-13.
[19] Kost GJ, Dohner J, Liu J, Ramos D, Haider N, Thalladi V. Web-accessible critical limits and critical values for urgent clinician notification. Clin Chem Lab Med. 2024; 62(11): 2294-306.
[20] Meneguin S, Pollo B, Pollo CF, Segalla AVZ. The Role of Nursing in Rapid Response Teams in the Care of Cardiorespiratory Arrest: An Integrative Review.
[21] Marcano Elola M. Reanimación cardiopulmonar. Últimas actualizaciones 2024.
[22] Sacristán Valero, Ana, Begoña Zalba Etayo, and José Luis Cabrerizo García. "Parada cardiaca intrahospitalaria, evolución y pronóstico. 2024.
[23] Arano DLP, Rodríguez TJA, Ramírez CAA, Ramírez LAP, Stoto AO. El rol de Enfermería en la toma de decisiones clínicas: desafíos y estrategias para una atención centrada en el paciente. RECIE FEC-UAS Revista de educación y cuidado integral en enfermería Facultad Enfermería Culiacán. 2025; 2(3): [154-61 pp.].
[24] Shaw A, Cabrejo PT, Adamczyk A, Mulcahey MJ. Reducing Hospital Readmissions of Older Adults Pursuing Postacute Care at Skilled Nursing Facilities: A Scoping Review. The American journal of occupational therapy: official publication of the American Occupational Therapy Association. 2022; 76(1): 1-8.
[25] Mikhail J, King L. Exploration of Ward-Based Nurses' Perspectives on Their Preparedness to Recognize Clinical Deterioration: A Scoping Review. Journal of patient safety. 2022.
Cite This Article
  • APA Style

    Molina, H. R. (2025). Deteriorating Patient: A Necessary Definition for Cardiac Arrest Prevention. American Journal of Nursing and Health Sciences, 6(3), 55-58. https://doi.org/10.11648/j.ajnhs.20250603.14

    Copy | Download

    ACS Style

    Molina, H. R. Deteriorating Patient: A Necessary Definition for Cardiac Arrest Prevention. Am. J. Nurs. Health Sci. 2025, 6(3), 55-58. doi: 10.11648/j.ajnhs.20250603.14

    Copy | Download

    AMA Style

    Molina HR. Deteriorating Patient: A Necessary Definition for Cardiac Arrest Prevention. Am J Nurs Health Sci. 2025;6(3):55-58. doi: 10.11648/j.ajnhs.20250603.14

    Copy | Download

  • @article{10.11648/j.ajnhs.20250603.14,
      author = {Hector Roche Molina},
      title = {Deteriorating Patient: A Necessary Definition for Cardiac Arrest Prevention
    },
      journal = {American Journal of Nursing and Health Sciences},
      volume = {6},
      number = {3},
      pages = {55-58},
      doi = {10.11648/j.ajnhs.20250603.14},
      url = {https://doi.org/10.11648/j.ajnhs.20250603.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajnhs.20250603.14},
      abstract = {Backgraund: Clinical deterioration not promptly recognized can result in increased patient morbidity and mortality. Early warning of cardiac arrest is a criterion commonly used in nursing staff's daily practice to identify patient deterioration. However, it is not always clear what a deteriorating patient means. Objetives: Provide an evidence-based approach to creating the definition of deteriorating patient Contextualize the definition of a deteriorating patient. Methods: A documentary review study was conducted through a bibliographic search of the databases to address the term deteriorating patient. Information about deteriorating patients was collected. Conclusion: As a result, valuable data were obtained to conceptualize the term deteriorated patient in nursing practice.
    },
     year = {2025}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Deteriorating Patient: A Necessary Definition for Cardiac Arrest Prevention
    
    AU  - Hector Roche Molina
    Y1  - 2025/09/08
    PY  - 2025
    N1  - https://doi.org/10.11648/j.ajnhs.20250603.14
    DO  - 10.11648/j.ajnhs.20250603.14
    T2  - American Journal of Nursing and Health Sciences
    JF  - American Journal of Nursing and Health Sciences
    JO  - American Journal of Nursing and Health Sciences
    SP  - 55
    EP  - 58
    PB  - Science Publishing Group
    SN  - 2994-7227
    UR  - https://doi.org/10.11648/j.ajnhs.20250603.14
    AB  - Backgraund: Clinical deterioration not promptly recognized can result in increased patient morbidity and mortality. Early warning of cardiac arrest is a criterion commonly used in nursing staff's daily practice to identify patient deterioration. However, it is not always clear what a deteriorating patient means. Objetives: Provide an evidence-based approach to creating the definition of deteriorating patient Contextualize the definition of a deteriorating patient. Methods: A documentary review study was conducted through a bibliographic search of the databases to address the term deteriorating patient. Information about deteriorating patients was collected. Conclusion: As a result, valuable data were obtained to conceptualize the term deteriorated patient in nursing practice.
    
    VL  - 6
    IS  - 3
    ER  - 

    Copy | Download

Author Information