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Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India

Received: 29 December 2013     Published: 20 February 2014
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Abstract

Background:- Syphilis generally considered to be a sexually transmitted disease, can also be transmitted in utero, and rarely by blood transfusion or non-sexual contact and is characterized by episodes of active disease, interrupted by latency. Congenital syphilis poses a significant challenge especially because infants may be still born, asymptomatic or present with a variable clinical picture at birth. Syphilis has been implicated in increasing susceptibility to HIV infection. We under took this study to determine the seroprevalence of syphilis in a tertiary care setting of Northern India and to identify an association with HIV-infection. Material & Method: - Of the total 19860 samples received during 5 years, VDRL was performed on 19860 samples and TPHA on 65 samples. Results: - 65 (0.33%) were found to be positive by VDRL. The patient’s positive for syphilis included 23 pregnant females (0.15% of the ANC samples received), 14(21.5%) HIV positive patients, 24 were from STD clinic (2.3% of the samples received from STD clinic). Conclusions: - The strong association between syphilis and HIV seroprevelence in this study suggests that acceleration of direct linkages between STI testing and HIV counseling and testing will be useful in enhancing the control of STI and HIV in India.

Published in American Journal of Internal Medicine (Volume 2, Issue 1)
DOI 10.11648/j.ajim.20140201.12
Page(s) 6-9
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Syphilis, VDRL, TPHA, HIV, ANC

References
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    Nazish Fatima, Abida Malik, Parvez Anwar Khan, Sana Ali, Haris Manzoor Khan, et al. (2014). Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India. American Journal of Internal Medicine, 2(1), 6-9. https://doi.org/10.11648/j.ajim.20140201.12

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    ACS Style

    Nazish Fatima; Abida Malik; Parvez Anwar Khan; Sana Ali; Haris Manzoor Khan, et al. Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India. Am. J. Intern. Med. 2014, 2(1), 6-9. doi: 10.11648/j.ajim.20140201.12

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    AMA Style

    Nazish Fatima, Abida Malik, Parvez Anwar Khan, Sana Ali, Haris Manzoor Khan, et al. Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India. Am J Intern Med. 2014;2(1):6-9. doi: 10.11648/j.ajim.20140201.12

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  • @article{10.11648/j.ajim.20140201.12,
      author = {Nazish Fatima and Abida Malik and Parvez Anwar Khan and Sana Ali and Haris Manzoor Khan and Nabeela},
      title = {Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India},
      journal = {American Journal of Internal Medicine},
      volume = {2},
      number = {1},
      pages = {6-9},
      doi = {10.11648/j.ajim.20140201.12},
      url = {https://doi.org/10.11648/j.ajim.20140201.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20140201.12},
      abstract = {Background:- Syphilis generally considered to be a sexually transmitted disease, can also be transmitted in utero, and rarely by blood transfusion or non-sexual contact and is characterized by episodes of active disease, interrupted by latency. Congenital syphilis poses a significant challenge especially because infants may be still born, asymptomatic or present with a variable clinical picture at birth. Syphilis has been implicated in increasing susceptibility to HIV infection. We under took this study to determine the seroprevalence of syphilis in a tertiary care setting of Northern India and to identify an association with HIV-infection. Material & Method: - Of the total 19860 samples received during 5 years, VDRL was performed on 19860 samples and TPHA on 65 samples. Results: - 65 (0.33%) were found to be positive by VDRL. The patient’s positive for syphilis included 23 pregnant females (0.15% of the ANC samples received), 14(21.5%) HIV positive patients, 24 were from STD clinic (2.3% of the samples received from STD clinic). Conclusions: - The strong association between syphilis and HIV seroprevelence in this study suggests that acceleration of direct linkages between STI testing and HIV counseling and testing will be useful in enhancing the control of STI and HIV in India.},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India
    AU  - Nazish Fatima
    AU  - Abida Malik
    AU  - Parvez Anwar Khan
    AU  - Sana Ali
    AU  - Haris Manzoor Khan
    AU  - Nabeela
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    PY  - 2014
    N1  - https://doi.org/10.11648/j.ajim.20140201.12
    DO  - 10.11648/j.ajim.20140201.12
    T2  - American Journal of Internal Medicine
    JF  - American Journal of Internal Medicine
    JO  - American Journal of Internal Medicine
    SP  - 6
    EP  - 9
    PB  - Science Publishing Group
    SN  - 2330-4324
    UR  - https://doi.org/10.11648/j.ajim.20140201.12
    AB  - Background:- Syphilis generally considered to be a sexually transmitted disease, can also be transmitted in utero, and rarely by blood transfusion or non-sexual contact and is characterized by episodes of active disease, interrupted by latency. Congenital syphilis poses a significant challenge especially because infants may be still born, asymptomatic or present with a variable clinical picture at birth. Syphilis has been implicated in increasing susceptibility to HIV infection. We under took this study to determine the seroprevalence of syphilis in a tertiary care setting of Northern India and to identify an association with HIV-infection. Material & Method: - Of the total 19860 samples received during 5 years, VDRL was performed on 19860 samples and TPHA on 65 samples. Results: - 65 (0.33%) were found to be positive by VDRL. The patient’s positive for syphilis included 23 pregnant females (0.15% of the ANC samples received), 14(21.5%) HIV positive patients, 24 were from STD clinic (2.3% of the samples received from STD clinic). Conclusions: - The strong association between syphilis and HIV seroprevelence in this study suggests that acceleration of direct linkages between STI testing and HIV counseling and testing will be useful in enhancing the control of STI and HIV in India.
    VL  - 2
    IS  - 1
    ER  - 

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Author Information
  • Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

  • Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

  • Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

  • Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

  • Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

  • Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

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