| Peer-Reviewed

Physico-chemical Evaluation of the Efficiency of Ash from the Leaves of Ocimum gratissimum L. in Skin Healing

Received: 22 November 2019     Accepted: 7 December 2019     Published: 25 December 2019
Views:       Downloads:
Abstract

Ocimum gratissimum L. is a plant whose leaf ash is widely cited as having wound healing properties. This work therefore consists in verifying the healing activity of the ashes of the leaves of this plant. Different leaf samples of this plant were collected from four sites in the central region of Benin and six sites in the southern region. The leaves of this plant were treated and calcined in a muffle furnace at a temperature of 500°C. The mineral contents of the ashes obtained are determined by Scanning Electron Microscopy coupled with Energy Dispersive X-Emission Spectrometry (SEM/EDS). Each ash was also dissolved and the pH of the substrates obtained measured. The results obtained show that the various ashes are rich in minerals with antiseptic and anti-inflammatory properties such as zinc (3256ppm-5020pm), sulphur (1278ppm-3513pm) and selenium (186ppm-412pm). In addition, the ashes studied are slightly acidic and their presence in a wound would not favour the development of certain pathogenic bacteria such as Escherichia coli, Salmonella. The results obtained provide justification for the traditional use of Ocimum gratissimum L. leaf ash in the treatment of external wounds.

Published in American Journal of Applied Chemistry (Volume 7, Issue 6)
DOI 10.11648/j.ajac.20190706.15
Page(s) 180-184
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Ocimum gratissimum L., Zinc, Sulphur, Selenium, Antiseptic

References
[1] National policy on traditional medicine and regulation of herbal medicines: report of a WHO global survey. (2005). Genève, Organisation mondiale de la Santé.
[2] F. Assogba Komlan, N’Danikou S., J. Honfoga, C. Sossa Vihotogbé, A Mensah et S. Simon. (2015). Ocimum gratissimum L. (Tchiayo en Fongbé): Du jardin à la table. Bibliothèque Nationale (BN) du Bénin. ISBN: 978-99919-0-305-7, dépôt légal N°7697.
[3] Mendham J., Denney R. C., Barnes J. D., Thomas M. J. K. (2005). Analyse chimique quantitative de Vogel, 6ème édition. De Boeck Université.
[4] Rouessac F., Rouessac A., Cruché D. (2004). Analyse Chimique, Méthodes et techniques instrumentales modernes, 6ème édition; Dunod, Paris.
[5] Robaut F., Crisci A. (2005). Spectrométrie X par dispersion de longueur d’onde: aspects technologiques, Réunion de décembre du GN MEBA.
[6] Goldstein J. I, Newbury D. E, Joy D. C et al. (2003). Scanning Electron Microscopy and X-ray Microanalysis, 3rd edition, New York, éd. Kluwer Academic/Plenum Publishers.
[7] Hosgood G. (2006). Stages of wound healing and their clinical relevance. Vet Clin Small Anim, 36, 667–685.
[8] Giovanni Pomponio, Silvia Tedesco, Angela Peghetti, Tommaso Bianchi, Sara Rowan, Alessandro Greco, Keith Cutting, Patricia Price, Zena Moore, Armando Gabrielli and Randall Wolcott. (2019). Improving the quality of clinical research on chronic wound infection treatment: expert-based recommendations. Journal of Wound Care. 10.12968, 28, Sup1, S26-S31.
[9] George Han and Roger Ceilley. (2017). Chronic Wound Healing: A Review of Current Management and Treatments, Advances in Therapy, 10.1007, 34, 3, (599-610).
[10] Omidreza Zekavat, Aida Amanat, Mohammadyasin Karami, Shahram Paydar, Bita Gramizadeh and Maryam Zareian-Jahromi. (2016). Wound Healing Studies Using Punica granatum Peel, Advances in Skin & Wound Care, 10.1097, 29, 5, 217-225.
[11] Usha R., Ramasami T. (2004). “The effects of urea and n-propanol on collagen denaturation: using DSC, circular dichroïsm and viscisity”, Thermochim Acta., 409, 201-206.
[12] Gantwerker EA, Hom DB. (2011). Skin: histology and physiology of wound healing. Facial Plast Surg Clin N Am. 19 (3): 441-53.
[13] B. Brigo. (1993). La Logique des oligoéléments: questions-réponses. Propriétés et applications thérapeutiques. Schémas de synthèse. Boiron.
[14] Stéphane Berthélémy. (2008.) «Les oligoéléments, généralités et macroéléments», Actual. Pharm., vol. 47, no 472, p. 6.
[15] J.-P. Douart. (1994). L’oligothérapie en pathologie fonctionnelle: données scientifiques et cliniques. Maloine.
[16] Maverakis E, Fung MA, Lynch PJ, Draznin M, Michael DJ, RubenB, et al. (2007). Acrodermatitis enteropathica and an overview of zincmetabolism. J Am Acad Dermatol. 56: 116—24.
[17] H. K. Biesalski et al. (2017). Atlas de poche de nutrition. Lavoisier – Médecine sciences.
[18] S. Berthélémy. (2008). «Oligoéléments, des microéléments pour l’oligothérapie», Actual. Pharm., vol. 47, no 480.
[19] M. Ferry. (2012). «18 - Les oligoéléments et les minéraux», in Nutrition De la Personne âgée, 4e édition., Elsevier Masson.
[20] C. Binet. (2007). Oligo-éléments et oligothérapie. Dangles.
[21] Apimondia. (2001). La médecine par les abeilles: traité d’apithérapie [CD-ROM]. Apimondia Standing Commission of Apitherapy.
[22] Cooperr A., Molan R. C., Harding K. G. (1999). Antibacterial activity of honey against strains of Staphylococcus aureus from infected wound. Journal Royal of the Society of Medicine, 92, 283-5.
[23] Magalon G., Vanwijck R. (2003). Guide des plaies: du pansement à la chirurgie. John Libbey Eurotext Ed., p. 104.
Cite This Article
  • APA Style

    Togbe Finagnon Crepin Alexis, Yete Pelagie, Yovo Franck, Wotto Valentin, Sohounhloue Dominique. (2019). Physico-chemical Evaluation of the Efficiency of Ash from the Leaves of Ocimum gratissimum L. in Skin Healing. American Journal of Applied Chemistry, 7(6), 180-184. https://doi.org/10.11648/j.ajac.20190706.15

    Copy | Download

    ACS Style

    Togbe Finagnon Crepin Alexis; Yete Pelagie; Yovo Franck; Wotto Valentin; Sohounhloue Dominique. Physico-chemical Evaluation of the Efficiency of Ash from the Leaves of Ocimum gratissimum L. in Skin Healing. Am. J. Appl. Chem. 2019, 7(6), 180-184. doi: 10.11648/j.ajac.20190706.15

    Copy | Download

    AMA Style

    Togbe Finagnon Crepin Alexis, Yete Pelagie, Yovo Franck, Wotto Valentin, Sohounhloue Dominique. Physico-chemical Evaluation of the Efficiency of Ash from the Leaves of Ocimum gratissimum L. in Skin Healing. Am J Appl Chem. 2019;7(6):180-184. doi: 10.11648/j.ajac.20190706.15

    Copy | Download

  • @article{10.11648/j.ajac.20190706.15,
      author = {Togbe Finagnon Crepin Alexis and Yete Pelagie and Yovo Franck and Wotto Valentin and Sohounhloue Dominique},
      title = {Physico-chemical Evaluation of the Efficiency of Ash from the Leaves of Ocimum gratissimum L. in Skin Healing},
      journal = {American Journal of Applied Chemistry},
      volume = {7},
      number = {6},
      pages = {180-184},
      doi = {10.11648/j.ajac.20190706.15},
      url = {https://doi.org/10.11648/j.ajac.20190706.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20190706.15},
      abstract = {Ocimum gratissimum L. is a plant whose leaf ash is widely cited as having wound healing properties. This work therefore consists in verifying the healing activity of the ashes of the leaves of this plant. Different leaf samples of this plant were collected from four sites in the central region of Benin and six sites in the southern region. The leaves of this plant were treated and calcined in a muffle furnace at a temperature of 500°C. The mineral contents of the ashes obtained are determined by Scanning Electron Microscopy coupled with Energy Dispersive X-Emission Spectrometry (SEM/EDS). Each ash was also dissolved and the pH of the substrates obtained measured. The results obtained show that the various ashes are rich in minerals with antiseptic and anti-inflammatory properties such as zinc (3256ppm-5020pm), sulphur (1278ppm-3513pm) and selenium (186ppm-412pm). In addition, the ashes studied are slightly acidic and their presence in a wound would not favour the development of certain pathogenic bacteria such as Escherichia coli, Salmonella. The results obtained provide justification for the traditional use of Ocimum gratissimum L. leaf ash in the treatment of external wounds.},
     year = {2019}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Physico-chemical Evaluation of the Efficiency of Ash from the Leaves of Ocimum gratissimum L. in Skin Healing
    AU  - Togbe Finagnon Crepin Alexis
    AU  - Yete Pelagie
    AU  - Yovo Franck
    AU  - Wotto Valentin
    AU  - Sohounhloue Dominique
    Y1  - 2019/12/25
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ajac.20190706.15
    DO  - 10.11648/j.ajac.20190706.15
    T2  - American Journal of Applied Chemistry
    JF  - American Journal of Applied Chemistry
    JO  - American Journal of Applied Chemistry
    SP  - 180
    EP  - 184
    PB  - Science Publishing Group
    SN  - 2330-8745
    UR  - https://doi.org/10.11648/j.ajac.20190706.15
    AB  - Ocimum gratissimum L. is a plant whose leaf ash is widely cited as having wound healing properties. This work therefore consists in verifying the healing activity of the ashes of the leaves of this plant. Different leaf samples of this plant were collected from four sites in the central region of Benin and six sites in the southern region. The leaves of this plant were treated and calcined in a muffle furnace at a temperature of 500°C. The mineral contents of the ashes obtained are determined by Scanning Electron Microscopy coupled with Energy Dispersive X-Emission Spectrometry (SEM/EDS). Each ash was also dissolved and the pH of the substrates obtained measured. The results obtained show that the various ashes are rich in minerals with antiseptic and anti-inflammatory properties such as zinc (3256ppm-5020pm), sulphur (1278ppm-3513pm) and selenium (186ppm-412pm). In addition, the ashes studied are slightly acidic and their presence in a wound would not favour the development of certain pathogenic bacteria such as Escherichia coli, Salmonella. The results obtained provide justification for the traditional use of Ocimum gratissimum L. leaf ash in the treatment of external wounds.
    VL  - 7
    IS  - 6
    ER  - 

    Copy | Download

Author Information
  • Department of Chemistry, Faculty of Science and Technology, University of Abomey-Calavi, Abomey-Calavi, Benin

  • Department of Chemistry, Faculty of Science and Technology, University of Abomey-Calavi, Abomey-Calavi, Benin

  • Department of Chemistry, Faculty of Science and Technology, University of Abomey-Calavi, Abomey-Calavi, Benin

  • Department of Chemistry, Faculty of Science and Technology, University of Abomey-Calavi, Abomey-Calavi, Benin

  • Department of Chemical Engineering-Processes, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, Benin

  • Sections