Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients
International Journal of Clinical Oncology and Cancer Research
Volume 4, Issue 3, June 2019, Pages: 29-33
Received: Aug. 13, 2019; Accepted: Sep. 5, 2019; Published: Sep. 18, 2019
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Mwenze Didier, Department of Pathology, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Kyabu Veronique, Department of Pathology, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Mukalay Abdon, Department of Public Health, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Kalenga Prosper, Department of Gynecology Obstetrics, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Ilunga Julien, Department of Pathology, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
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The aim of this study is to show the relationship between the index of Papillomavirus infection and the grade of cervical intraepithelial neoplasia as proposed by WHO in Lubumbashi patients. This is a cross-sectional analytical study on cervical biopsies whose histological diagnosis is an intraepithelial neoplasia registered in two Laboratory of Patholoy in Lubumbashi for a period of two years from June 2017 to June 2019. The following results were observed: A total of 41 cases of intraepithelial neoplasia were recorded out of 91 cervical biopsies is 43.2%. Five indices of Human Papillomavirus infection are found in Lubumbashi patients in variable proportions without statistically significant difference; that is the index (5) in 29.27%, the indices (7) and (9) in 21.95% for each index, the index (6) in 17.07% and the index (8) in 9.76%. The three grades of intraepithelial neoplasia proposed by the WHO since 2003 are also found in Lubumbashi patients in varying proportions with no statistically significant difference; 48.78% for grade 3; 36.59% for grade 2 and 14.63% for grade 1. There is no relationship between the HPV infection index and the grade of cervical intraepithelial neoplasia; calculated linear correlation r ^ 2 is equal to 0.00.
Papillomavirus Index, Intra-Epithelial Neoplasia, Grade
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Mwenze Didier, Kyabu Veronique, Mukalay Abdon, Kalenga Prosper, Ilunga Julien, Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients, International Journal of Clinical Oncology and Cancer Research. Vol. 4, No. 3, 2019, pp. 29-33. doi: 10.11648/j.ijcocr.20190403.11
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