Introduction: The diagnosis of pheocytochroma is often late compared to the appearance of symptoms, sources of morbidity and even mortality. However, pheochromocytoma can be discovered incidentally during a pathology unrelated to the tumor. Case report: We report a case revealed by acute viral hepatitis B. It’s a young subject hospitalized in the internal medicine department of the Sylvanus OlympioTeaching Hospital in Lome. This is a 22-year-old patient, professional driver with no known pathological history, admitted for headache, muscle aches and asthenia associated with abdominal pain and postprandial vomiting in a febrile context. In admission, clinical examination revealed high blood pressure (BP=190/140mmHg), a deterioration in general condition, jaundice and painful hepatomegaly. The biological assessment revealed a cholestatic cytolysis syndrome (AST: 48.24N, ALT: 42.23N, PAL: 1.06N, Gamma GT: 3.84N, total bilirubin: 31.4N, direct bilirubin: 89, 6N). The serological assessment revealed acute viral hepatitis B (HbsAg positive and anti-Hbc antibodies type IgM positive, HIV and hepatitis C serologies negative). An abdominal ultrasound noted homogeneous hepatomegaly without dilatation of the portal trunk or bile ducts. Faced with this hypertension in a 22-year-old, secondary hypertension was considered and abdominal CT revealed a pheochromocytoma. Conclusion: Pheochromocytoma is not uncommon in our circles. It should always be considered in the present of high blood pressing in young subject.
| Published in | International Journal of Clinical Oncology and Cancer Research (Volume 9, Issue 1) |
| DOI | 10.11648/ijcocr.20240901.12 |
| Page(s) | 11-14 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Viral Hepatitis B, Pheochromocytoma, Hypertension, Young Subject, Lomé (Togo)
| [1] | Fattorusso V, Ritter O. Clinical medicine: from diagnosis to treatment. Issy Moulineaux: Masson; 2016. |
| [2] | Bieleli E, Kandjingu K. Pheochromocytoma: diagnosis of 3 cases (from 14 suspicions). Black African medicine. 1990; 37(6): 338-41. |
| [3] | Sagna Y, Yanogo DAR, Guira O, Bagbila A, Tieno H., Drabo JY. Pheochromocytoma in Ouagadougou (Burkina Faso): about three cases. Annals of Endocrinology. 2014; 75(5–6): 473. |
| [4] | Hachlaf H, Madani A. Intraoperative fortuitous discovery of pheochromocytoma. Pan Afr Med J. 2018; 29: 142. |
| [5] | Laboureau S, Rohmer V. Pheochromocytoma and paraganglioma. Endocrinology-Nutrition 2013; doi: 10.1016/S1155-1941(23)43253-2. |
| [6] | Amar L, Gimenez-Roqueplo AP, Hernigou A, Plouin PF. Epidemiology and diagnosis of pheochromocytomas. Metabolisms Hormones Diabetes and Nutrition. 2006; 10(2): 56-60. |
| [7] | Kessie K, Agbere AD, Bahunde M, Banze A, Gnamey DK, Duaduvi Net al. Familial pheochromocytoma from an observation at Lomé University Hospital. Afr Noire Med. 1990; 37(9): 501-8. |
| [8] | Ait Laalim S, Rhazal F, El Mejdoubi S, Soufi M, Benzakri O et al. Bilateral pheochromocytoma. Morocco Medical. 2005; 27(4): 258-61. |
| [9] | Bah M. Pheochromocytoma at the Mali hospital: about an observation. Annals of Endocrinology 2014; 75(5–6): 365. |
| [10] | Doubi S, Aziouaz F, Agerd L., Ajdi F., 2014. Silent pheochromocytomas in 2 cases. Annals of Endocrinology. 2014; 75(5–6): 469. |
| [11] | Platts Jk, Drew Pj, Harvey Jn. et al. Death from phaeochromocytoma: lessons from a post-mortem survey. JR Coll Physicians Lond. 1995; 29(4): 299-306. |
| [12] | Myklejord DJ. Undiagnosed pheochromocytoma: the anesthesiologist nightmare. Clin Med Res 2004; 2(1): 59-62. |
| [13] | Dabbous A, Siddik-Sayyid S, Baraka A. et al. Catastrophic hemodynamic changes in a patient with undiagnosed pheochromocytoma undergoing abdominal hysterectomy. Anesth Analg. 2007; 104(1): 223-24. |
| [14] | Bensghir M, Elwali A, Lalaoui Sj, Kamili Nd, Alaoui H, Laoutid J et al. Management of undiagnosed pheochromocytoma with acute appendicitis. World J Emerg Surg. 2009; 4: 35. |
| [15] | El Bouazzaoui A, Hammas N, Houari1 N, Boukatta B, Oussaden A, Sbai H. Acute coronary syndrome: an uncommon manifestation of pheochromocytoma. Pan Afr Med J. 2015; 22: 151. |
| [16] | Sagna Y, Yanogo ARD, Gninkoun CJ, Bogounou R, Zoungrana L, Bagbila PA et al. A familial form of pheochromocytoma: about two observations in Ouagadougou (Burkina Faso). RAFMI 2017; 4(1-1): 56-60. |
| [17] | Mansmann G, Lau J, Balk E, Rothberg M, Miyachi Y, and Bornstein SR. The clinically inapparent adrenal mass: update in diagnosis and management. Endocr Rev 2004; 25(2): 309-40. |
| [18] | Mantero F, Terzolo M, Arnaldi G, Osella G, Masini AM, Alı̀ A & Study Group on Adrenal Tumors of the Italian Society of Endocrinology. A survey on adrenal incidentaloma in Italy. Study Group on Adrenal Tumors of the Italian Society of Endocrinology. J Clin Endocrinol Metab. 2000; 85(2): 637-44. |
| [19] | Kolou M, Nadjir LK, Anyovi F, Katawa G, Abaltou B, Salou M. Seroprevalence of viral hepatitis B and C in the general population of Lomé. J Rech Sci University of Lomé. 2018; 20(1): 225-33. |
| [20] | Mbaye PS, Ranandineau Y, Diallo A, Haudrechy D, Sane M, Michel G. Hepatitis B virus and chronic liver disease in Dakar. Case-control studies. Med. Too much. 2000; 60: 47-52. |
| [21] | Baïzri H, Youssef Y, Elhadri S, Elanzaoui J, Chahbi Z, Kaddouri S et al. Hepatic cytolysis revealing an adrenal ganglioneuroma. Pan Afri Med J. 2014; 17: 224. |
| [22] | Brunaud L, Ayav A, Bresler L, Klein M, Boisel P. Diagnostic problems of pheochromocytoma. Annals of Surgery. 2005; 130: 26-272. |
| [23] | Mannelli M, Ianni L et al. Pheochromocytoma in Italy: a multicentric retrospective study. Eur J Endocrinol 1999; 141(6): 619-24. |
| [24] | Lenders JWM, Duh QY, Elsenhofer G, Gimenez-Roqueplo AP, Greb SKG et al. Pheochromocytoma and paraganlioma: an endocrine society clinical practice guideline. /On Endocrinol metab. 2014; 99: 1915-1942. |
| [25] | Plouin PF, Amar L, Dekkers OM, Fassnacht M, Gimenez-Roqueplo AP et al. Guideline working group. European Society of Endocrinology Clinical Practice Guideline for long term follow up of patient operated on for a pheochromocytoma or a paraganglioma. Eur J Endocrinol. 2016; 174: G1-G10. |
| [26] | Findeis-Hosey JJ, McMahon KQ, Findeis SK. Von Hippel Lindau disease. J Pediatr Genet. 2016; 5: 116-123. |
| [27] | Hirbe AC, Gutmann DH. Neurofibromatosis type 1: a multidisciplinary approach to care. Lancet Neurol. 2014; 13: 834-843. |
| [28] | Wohlik N, Schweizer H, Erlic Z, Scmid KW, Walz MK et al. Multiple endocrine neoplasia type 2. Best Pract Res Clin Endocrinol Metab. 2010; 24: 371-387. |
APA Style
Lihanimpo, D., Dzidzonu, N. K., Toyi, T., Edem, M. K., Agbéko, D. K., et al. (2024). Pheochromocytoma Discovered Incidentally at the Sylvanus Olympio University Hospital in Lomé (Togo). International Journal of Clinical Oncology and Cancer Research, 9(1), 11-14. https://doi.org/10.11648/ijcocr.20240901.12
ACS Style
Lihanimpo, D.; Dzidzonu, N. K.; Toyi, T.; Edem, M. K.; Agbéko, D. K., et al. Pheochromocytoma Discovered Incidentally at the Sylvanus Olympio University Hospital in Lomé (Togo). Int. J. Clin. Oncol. Cancer Res. 2024, 9(1), 11-14. doi: 10.11648/ijcocr.20240901.12
AMA Style
Lihanimpo D, Dzidzonu NK, Toyi T, Edem MK, Agbéko DK, et al. Pheochromocytoma Discovered Incidentally at the Sylvanus Olympio University Hospital in Lomé (Togo). Int J Clin Oncol Cancer Res. 2024;9(1):11-14. doi: 10.11648/ijcocr.20240901.12
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Download@article{10.11648/ijcocr.20240901.12,
author = {Djalogue Lihanimpo and Nemi Komi Dzidzonu and Tchamdja Toyi and Mossi Komi Edem and Djagadou Kodjo Agbéko and Balaka Abago and Djibril Mohaman Awalou},
title = {Pheochromocytoma Discovered Incidentally at the Sylvanus Olympio University Hospital in Lomé (Togo)},
journal = {International Journal of Clinical Oncology and Cancer Research},
volume = {9},
number = {1},
pages = {11-14},
doi = {10.11648/ijcocr.20240901.12},
url = {https://doi.org/10.11648/ijcocr.20240901.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.ijcocr.20240901.12},
abstract = {Introduction: The diagnosis of pheocytochroma is often late compared to the appearance of symptoms, sources of morbidity and even mortality. However, pheochromocytoma can be discovered incidentally during a pathology unrelated to the tumor. Case report: We report a case revealed by acute viral hepatitis B. It’s a young subject hospitalized in the internal medicine department of the Sylvanus OlympioTeaching Hospital in Lome. This is a 22-year-old patient, professional driver with no known pathological history, admitted for headache, muscle aches and asthenia associated with abdominal pain and postprandial vomiting in a febrile context. In admission, clinical examination revealed high blood pressure (BP=190/140mmHg), a deterioration in general condition, jaundice and painful hepatomegaly. The biological assessment revealed a cholestatic cytolysis syndrome (AST: 48.24N, ALT: 42.23N, PAL: 1.06N, Gamma GT: 3.84N, total bilirubin: 31.4N, direct bilirubin: 89, 6N). The serological assessment revealed acute viral hepatitis B (HbsAg positive and anti-Hbc antibodies type IgM positive, HIV and hepatitis C serologies negative). An abdominal ultrasound noted homogeneous hepatomegaly without dilatation of the portal trunk or bile ducts. Faced with this hypertension in a 22-year-old, secondary hypertension was considered and abdominal CT revealed a pheochromocytoma. Conclusion: Pheochromocytoma is not uncommon in our circles. It should always be considered in the present of high blood pressing in young subject.
},
year = {2024}
}
TY - JOUR T1 - Pheochromocytoma Discovered Incidentally at the Sylvanus Olympio University Hospital in Lomé (Togo) AU - Djalogue Lihanimpo AU - Nemi Komi Dzidzonu AU - Tchamdja Toyi AU - Mossi Komi Edem AU - Djagadou Kodjo Agbéko AU - Balaka Abago AU - Djibril Mohaman Awalou Y1 - 2024/02/05 PY - 2024 N1 - https://doi.org/10.11648/ijcocr.20240901.12 DO - 10.11648/ijcocr.20240901.12 T2 - International Journal of Clinical Oncology and Cancer Research JF - International Journal of Clinical Oncology and Cancer Research JO - International Journal of Clinical Oncology and Cancer Research SP - 11 EP - 14 PB - Science Publishing Group SN - 2578-9511 UR - https://doi.org/10.11648/ijcocr.20240901.12 AB - Introduction: The diagnosis of pheocytochroma is often late compared to the appearance of symptoms, sources of morbidity and even mortality. However, pheochromocytoma can be discovered incidentally during a pathology unrelated to the tumor. Case report: We report a case revealed by acute viral hepatitis B. It’s a young subject hospitalized in the internal medicine department of the Sylvanus OlympioTeaching Hospital in Lome. This is a 22-year-old patient, professional driver with no known pathological history, admitted for headache, muscle aches and asthenia associated with abdominal pain and postprandial vomiting in a febrile context. In admission, clinical examination revealed high blood pressure (BP=190/140mmHg), a deterioration in general condition, jaundice and painful hepatomegaly. The biological assessment revealed a cholestatic cytolysis syndrome (AST: 48.24N, ALT: 42.23N, PAL: 1.06N, Gamma GT: 3.84N, total bilirubin: 31.4N, direct bilirubin: 89, 6N). The serological assessment revealed acute viral hepatitis B (HbsAg positive and anti-Hbc antibodies type IgM positive, HIV and hepatitis C serologies negative). An abdominal ultrasound noted homogeneous hepatomegaly without dilatation of the portal trunk or bile ducts. Faced with this hypertension in a 22-year-old, secondary hypertension was considered and abdominal CT revealed a pheochromocytoma. Conclusion: Pheochromocytoma is not uncommon in our circles. It should always be considered in the present of high blood pressing in young subject. VL - 9 IS - 1 ER -
Department of Internal Medicine, University of Kara, Kara, Togo
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