Breast Cancer: Clinical and Pathological Study at Lubumbashi and Kinshasa University Hospitals in the Democratic Republic of the Congo from 2014 to 2015
International Journal of Clinical Oncology and Cancer Research
Volume 2, Issue 6, December 2017, Pages: 141-148
Received: Aug. 27, 2017; Accepted: Sep. 21, 2017; Published: Jan. 3, 2018
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Authors
Nday Guy, Surgery Department, University Hospital of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Kabamba Michel, Department of Public Health, University of Kamina, Kamina, Democratic Republic of Congo
Mukalay Abdon, Clinical Epidemiology Unit and Tropical Pathologies, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Tshilombo François, Surgery Department, University Hospital of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Odimba Etienne, Surgery Department, University Hospital of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Lebwaz Bienvenu, Pathology Department, University Hospital of Kinshasa, University of Kinshasa, Kamina, Democratic Republic of Congo
Kalenga Prospère, Department of Obstetrics and Gynecology, University Hospital of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Ilunga Julien, Pathology Department, University Hospital of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
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Abstract
Often tumors in the African setting are described aggressive with high grading status. There is no national cancer registry nor suitable data on breast cancer in DRC. Better knowledge of this entity can improve its management. To demonstrate the clinical and pathological profile of breast cancer in Kinshasa and Lubumbashi (DR Congo). Cross-sectional study of 86 patients were included for clinical and pathological in the Cities of Lubumbashi and Kinshasa from 2014-2016. All cases were women with histological invasive breast carcinoma. Parameters studied were: age of patients at diagnosis, morphological type [33], grade [23] of tumor, tumor necrosis and Nottingham score. Statistical analysis used SPSS program and Pearson Khi-square test. From January 2014 to September 2016, 86 cases were reviewed. The average age of patients at diagnosis was 47.8 ± 12.1 years. In 74% of cases, patients were presented at stage T3 or T4. The average size of tumors was 6.6 ± 2.7 cm. Invasive Ductular carcinoma was found in 97.2% of cases. Grade 3 tumors were found in 54.7% and grade 1 in 4.7%. Tumor necrosis was present in 30.2% of biopsies. The Nottingham score higher than 5.4 was found in 62.8%. All the patients were treated by supra-radical mastectomy. Lymph nodes were numbered in each case. Prognosis of breast cancers is poor in Lubumbashi and Kinshasa University Hospitals for tumors are diagnosed later. To improve breast cancer management, tumor must be diagnosed earlier. Perception of this pathology and its correct assessment are important for better taking care in the Democratic Republic of the Congo.
Keywords
Breast Carcinoma, Clinico-Pathological Evaluation, Prognosis
To cite this article
Nday Guy, Kabamba Michel, Mukalay Abdon, Tshilombo François, Odimba Etienne, Lebwaz Bienvenu, Kalenga Prospère, Ilunga Julien, Breast Cancer: Clinical and Pathological Study at Lubumbashi and Kinshasa University Hospitals in the Democratic Republic of the Congo from 2014 to 2015, International Journal of Clinical Oncology and Cancer Research. Vol. 2, No. 6, 2017, pp. 141-148. doi: 10.11648/j.ijcocr.20170206.13
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Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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