American Journal of Life Sciences

Volume 3, Issue 2, March 2015

  • Gene Expression Study on Similarity Effect of Thymoquinone on Epithelial Breast Cancer and Colorectal Cancer Cell Lines

    Marjaneh Motaghed

    Issue: Volume 3, Issue 2-2, March 2015
    Pages: 1-6
    Received: 09 December 2014
    Accepted: 17 December 2014
    Published: 27 December 2014
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    This article belongs to the Special Issue The Most Effective Medicinal Plants in Cancer Treatment
    Abstract: Adenocarcinoma is known as a common type of cancer which includes 85% of breast carcinoma and 95% of colorectal carcinoma. Up until now, the cytotoxic effect of Thymoquinone on different types of tumor cells has been reported. It was hypothesized that Thymoquinone has similar effect on cancer arising from epithelial cells through gene expression an... Show More
  • Cytotoxic, Cytostatic and Anti-Estrogenic Effect of Thymoquinone on Estrogen Receptor-Positive Breast Cancer MCF7 Cell Line

    Marjaneh Motaghed

    Issue: Volume 3, Issue 2-2, March 2015
    Pages: 7-14
    Received: 10 December 2014
    Accepted: 13 December 2014
    Published: 27 December 2014
    Downloads:
    Views:
    This article belongs to the Special Issue The Most Effective Medicinal Plants in Cancer Treatment
    Abstract: About 80% of breast cancers are estrogen-receptor positive. The research carried out herein focused on the effect of Thymoquinone which is an active compound of Nigella sativa seed on estrogen-receptor positive breast cancer MCF7 cell line. The percentage of apoptotic cells was found using Annexin V-FITC apoptosis detection kit. CycleTEST PLUS DNA ... Show More