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Practices and Factors for Self-Medication with Antibiotics Among Patients and Medical Students in Tunisia: A Cross-Sectional Study

Received: 10 November 2022    Accepted: 25 November 2022    Published: 9 January 2023
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Abstract

Self-medication with antibiotics (SMA) becomes generally common practice due to multiple factors. This study aimed to identify the prevalence and factors associated with SMA among patients and medical students in Tunisia. A cross-sectional study was conducted between March 2018 and October 2018 on 752 subjects. The sample of this study consisted of 153 patients in the outpatient clinic of two Universities Hospitals (Habib Bourguiba and Hedi Chaker in Sfax, Tunisia) and 559 students in the Medical universities of Tunisia. The inclusion criteria included adult patients (≥18 years) who see in one of both hospitals during the study and Medical students who accepted to access the questionnaire on Google forms. Data were collected through a structured questionnaire reliable and validated by a pilot test in a subsample of participants. Data were analyzed using SPSS. Student’s t-test and Mann-Whitney U test were used to compare differences between quantitative variables. Pearson's chi-square test was carried out to evaluate associations between qualitative variables. Of 752 participants, 71.68% self-medicated (70.9% of patients and 72% of medical students). There were no significant differences in SMA between patients and medical students (P=0.738). Amoxicillin was the most commonly used antibiotic for SM by patients (67.6%) and medical students (74.5%) (P=0.149). Furthermore, the most common indications for the use of self-medicated antibiotics were angina, influenza-like illness, and fever were the most frequent indications for the use of self-medicated antibiotics by patients (56.5%, 60.2%, 28.7%) and medical students (60.1%, 40.8%, 17.9%) (P=0.494, P=0.001, P=0.012). Furthermore, for reasons following previous experience, time-saving, and easy availability of drugs from pharmacies, the difference was statistically different between the two groups, with an increase in medical students compared to patients. The major source of information was pharmacies. Ninety-seven patients (90%) and 364 students (88.8%) got their antibiotics based on pharmacist consultancy. SMA is a common practice among patients and medical students in Tunisia. This infers the need for interventions to prevent the SMA, such as the implementation of appropriate health organizations for public education concerning the risks and consequences for the health of SMA.

Published in World Journal of Medical Case Reports (Volume 4, Issue 1)
DOI 10.11648/j.wjmcr.20230401.11
Page(s) 1-8
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Amoxicillin, Antibiotics, Medical Students, Pharmacies, Questionnaire, Self-Medication

References
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    Mariam Ammar, Mohamed Makhlouf, Soufiene Triki, Nour Ben Amor, Rawia Makni, et al. (2023). Practices and Factors for Self-Medication with Antibiotics Among Patients and Medical Students in Tunisia: A Cross-Sectional Study. World Journal of Medical Case Reports, 4(1), 1-8. https://doi.org/10.11648/j.wjmcr.20230401.11

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    Mariam Ammar; Mohamed Makhlouf; Soufiene Triki; Nour Ben Amor; Rawia Makni, et al. Practices and Factors for Self-Medication with Antibiotics Among Patients and Medical Students in Tunisia: A Cross-Sectional Study. World J. Med. Case Rep. 2023, 4(1), 1-8. doi: 10.11648/j.wjmcr.20230401.11

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    AMA Style

    Mariam Ammar, Mohamed Makhlouf, Soufiene Triki, Nour Ben Amor, Rawia Makni, et al. Practices and Factors for Self-Medication with Antibiotics Among Patients and Medical Students in Tunisia: A Cross-Sectional Study. World J Med Case Rep. 2023;4(1):1-8. doi: 10.11648/j.wjmcr.20230401.11

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  • @article{10.11648/j.wjmcr.20230401.11,
      author = {Mariam Ammar and Mohamed Makhlouf and Soufiene Triki and Nour Ben Amor and Rawia Makni and Takwa Lefi and Khaled Zeghal and Ahmed Hakim and Lobna Ben Mahmoud},
      title = {Practices and Factors for Self-Medication with Antibiotics Among Patients and Medical Students in Tunisia: A Cross-Sectional Study},
      journal = {World Journal of Medical Case Reports},
      volume = {4},
      number = {1},
      pages = {1-8},
      doi = {10.11648/j.wjmcr.20230401.11},
      url = {https://doi.org/10.11648/j.wjmcr.20230401.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjmcr.20230401.11},
      abstract = {Self-medication with antibiotics (SMA) becomes generally common practice due to multiple factors. This study aimed to identify the prevalence and factors associated with SMA among patients and medical students in Tunisia. A cross-sectional study was conducted between March 2018 and October 2018 on 752 subjects. The sample of this study consisted of 153 patients in the outpatient clinic of two Universities Hospitals (Habib Bourguiba and Hedi Chaker in Sfax, Tunisia) and 559 students in the Medical universities of Tunisia. The inclusion criteria included adult patients (≥18 years) who see in one of both hospitals during the study and Medical students who accepted to access the questionnaire on Google forms. Data were collected through a structured questionnaire reliable and validated by a pilot test in a subsample of participants. Data were analyzed using SPSS. Student’s t-test and Mann-Whitney U test were used to compare differences between quantitative variables. Pearson's chi-square test was carried out to evaluate associations between qualitative variables. Of 752 participants, 71.68% self-medicated (70.9% of patients and 72% of medical students). There were no significant differences in SMA between patients and medical students (P=0.738). Amoxicillin was the most commonly used antibiotic for SM by patients (67.6%) and medical students (74.5%) (P=0.149). Furthermore, the most common indications for the use of self-medicated antibiotics were angina, influenza-like illness, and fever were the most frequent indications for the use of self-medicated antibiotics by patients (56.5%, 60.2%, 28.7%) and medical students (60.1%, 40.8%, 17.9%) (P=0.494, P=0.001, P=0.012). Furthermore, for reasons following previous experience, time-saving, and easy availability of drugs from pharmacies, the difference was statistically different between the two groups, with an increase in medical students compared to patients. The major source of information was pharmacies. Ninety-seven patients (90%) and 364 students (88.8%) got their antibiotics based on pharmacist consultancy. SMA is a common practice among patients and medical students in Tunisia. This infers the need for interventions to prevent the SMA, such as the implementation of appropriate health organizations for public education concerning the risks and consequences for the health of SMA.},
     year = {2023}
    }
    

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    AU  - Mariam Ammar
    AU  - Mohamed Makhlouf
    AU  - Soufiene Triki
    AU  - Nour Ben Amor
    AU  - Rawia Makni
    AU  - Takwa Lefi
    AU  - Khaled Zeghal
    AU  - Ahmed Hakim
    AU  - Lobna Ben Mahmoud
    Y1  - 2023/01/09
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    DO  - 10.11648/j.wjmcr.20230401.11
    T2  - World Journal of Medical Case Reports
    JF  - World Journal of Medical Case Reports
    JO  - World Journal of Medical Case Reports
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    EP  - 8
    PB  - Science Publishing Group
    SN  - 2994-726X
    UR  - https://doi.org/10.11648/j.wjmcr.20230401.11
    AB  - Self-medication with antibiotics (SMA) becomes generally common practice due to multiple factors. This study aimed to identify the prevalence and factors associated with SMA among patients and medical students in Tunisia. A cross-sectional study was conducted between March 2018 and October 2018 on 752 subjects. The sample of this study consisted of 153 patients in the outpatient clinic of two Universities Hospitals (Habib Bourguiba and Hedi Chaker in Sfax, Tunisia) and 559 students in the Medical universities of Tunisia. The inclusion criteria included adult patients (≥18 years) who see in one of both hospitals during the study and Medical students who accepted to access the questionnaire on Google forms. Data were collected through a structured questionnaire reliable and validated by a pilot test in a subsample of participants. Data were analyzed using SPSS. Student’s t-test and Mann-Whitney U test were used to compare differences between quantitative variables. Pearson's chi-square test was carried out to evaluate associations between qualitative variables. Of 752 participants, 71.68% self-medicated (70.9% of patients and 72% of medical students). There were no significant differences in SMA between patients and medical students (P=0.738). Amoxicillin was the most commonly used antibiotic for SM by patients (67.6%) and medical students (74.5%) (P=0.149). Furthermore, the most common indications for the use of self-medicated antibiotics were angina, influenza-like illness, and fever were the most frequent indications for the use of self-medicated antibiotics by patients (56.5%, 60.2%, 28.7%) and medical students (60.1%, 40.8%, 17.9%) (P=0.494, P=0.001, P=0.012). Furthermore, for reasons following previous experience, time-saving, and easy availability of drugs from pharmacies, the difference was statistically different between the two groups, with an increase in medical students compared to patients. The major source of information was pharmacies. Ninety-seven patients (90%) and 364 students (88.8%) got their antibiotics based on pharmacist consultancy. SMA is a common practice among patients and medical students in Tunisia. This infers the need for interventions to prevent the SMA, such as the implementation of appropriate health organizations for public education concerning the risks and consequences for the health of SMA.
    VL  - 4
    IS  - 1
    ER  - 

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Author Information
  • Department of Pharmacology, Faculty of Medicine, University of S

  • Regional Directorate of Health, Sfax, Tunisia

  • Faculty of Medicine, University of Sfax, Sfax, Tunisia

  • Higher Institute of Nursing Sciences of Sfax, Sfax, Tunisia

  • Higher Institute of Nursing Sciences of Sfax, Sfax, Tunisia

  • Higher Institute of Nursing Sciences of Sfax, Sfax, Tunisia

  • Department of Pharmacology, Faculty of Medicine, University of S

  • Department of Pharmacology, Faculty of Medicine, University of S

  • Department of Pharmacology, Faculty of Medicine, University of S

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