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Prevalence of Thrombocytopenia Among Pregnant Women in Tripoli Region /Libya

Received: 2 October 2021    Accepted: 21 October 2021    Published: 29 October 2021
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Abstract

Thrombocytopenia is the definition of a condition in which the number of platelets is less than 150,000 / ml, and this deficiency may be the result of a lack of platelet production in the bone marrow or an increase in their breakdown in the connective tissue. This condition is common in pregnant women, with a global prevalence of about 7%. This study aims to find out the prevalence of this condition among pregnant women in the Tripoli area. A cross-sectional study design was used to assess the prevalence of thrombocytopenia among pregnant women who have visited the obstetrical ward department of obstetrics and gynecology in Al jalaa Hospital, Tripoli from January to April 2021. 1700 pregnant women have been included in the study during their follow-up in Al jalaa hospital of gynecology and obstetrics at the time of the study. 2 milliliters of venous blood were collected under aseptic conditions and transferred into (EDTA) tubes. The complete blood cell counts were determined using a Sysmex analyzer. Sony computer CORE i7 was used, bivariable statistical analysis was carried on using Microsoft office excel to evaluate the effect of an independent variable over the dependent variable. Results shows that 18% of pregnant women were thrombocytopenic; this thrombocytopenia was increased with age, upon the classification and severity of thrombocytopenia 78.5% were mild, and 21.5% were moderate thrombocytopenic with no sever cases. Conclusion: It can be concluded that thrombocytopenia disorders in pregnancy are very common in the Tripoli region, the prevalence of thrombocytopenia increased with the increase in the gestational age to reach the maximum at the third trimester of gestation.

Published in International Journal of Biomedical Science and Engineering (Volume 9, Issue 4)
DOI 10.11648/j.ijbse.20210904.12
Page(s) 83-88
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Thrombocytopenia, Pregnant Women, Gynecology and Obstetrics Al Jalaa Hospital

References
[1] Chandra S., Tripathi K., Mishra S., Amzarul M., and Vaish A. (2012). Physiological changes in hematological parameters during pregnancy. Indian J. Hematol. Blood Transfus., 28 (3): 144–146.
[2] Akinlaja O. (2016). Hematological changes in pregnancy – the preparation for intrapartum blood loss. Obstet. Gynecol. Int. J., 4 (3): 00109.
[3] Boehlen F. Thrombocytopenia during pregnancy: importance, diagnosis and management. Hamostaseologie. 2006; 26 (1): 72–74.
[4] Katke RD Gohil DP. Thrombocytopenia during pregnancy: an institutional based study. Int J Reprod Contracept Obstet Gynecol. 2014; 3 (4): 947–951.
[5] Burrows RF, Kelton JG. Fetal thrombocytopenia and its relation to maternal thrombocytopenia. N Engl J Med. 1993; 329 (20): 1463–1466.
[6] Ruggeri M, Schiavotto C, Castaman G, Tosetto A, Rodeghiero F. Gestational thrombocytopenia: a prospective study. Haematologica. 1997; 82 (3): 341–342.
[7] Samuels P, Bussel JB, Braitman LE, et al. Estimation of the risk of thrombocytopenia in the offspring of pregnant women with presumed immune thrombocytopenic purpura. N Engl J Med. 1990; 323 (4): 229–235.
[8] McCrae KR. Thrombocytopenia in pregnancy: differential diagnosis, pathogenesis, and management. Blood Rev. 2003; 17 (1): 7–14.
[9] Ballem PJ. Hematological problems of pregnancy. Can Fam Physician. 1988; 34: 2531–2537.
[10] Shehata N, Burrows R, Kelton JG. Gestational thrombocytopenia. Clin Obstet Gynecol. 1999; 42 (2): 327–334.
[11] Kadir RA, McLintock C. Thrombocytopenia and disorders of platelet function in pregnancy. Semin Thromb Hemost. 2011; 37 (6): 640–652.
[12] Vyas, Rupa, Shah S, et al. Comparative study of mild versus moderate to severe thrombocytopenia in third trimester of pregnancy in a tertiary care hospital. NHL J Med Sci. 2014; 3 (1): 8–11.
[13] Boehlen, F., Hohlfeld, P., Extermann, P., and de Moerloose, P. (1999). Maternal antiplatelet antibodies in predicting risk of neonatal thrombocytopenia. Obstet. Gynecol., 93 (2): 169-173.
[14] Webert, K. E., Mittal, R., Sigouin, C., Heddle, N. M., and Kelton, J. G. (2003). A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic purpura. Blood, 102 (13): 4306 - 4311.
[15] Mbanya. D., Claude, T. T., Takoeta, E., Mbu, R., and Kaptue, L. (2007). Factors associated with thrombocytopenia among pregnant women in Cameroon. Santé Montrouge France, 17 (4): 213 - 217.
[16] Al-Kouatly, H. B., Chasen, S. T., Kalish, R. B., and Chervenak, F. A. (2003). Causes of thrombocytopenia in triplet gestations. Amer. J. Obstet. Gynecol., 189 (1): 177-180.
[17] Olayemi E. and Akuffo F. W. (2012). Gestational thrombocytopenia among pregnant Ghanaian women. Pan African Med. J., 12: 34.
[18] Verdy, E., and Uzan, S. (1993). Groupe de travail sur les thrombope´nies maternelles et foetales. Plaquettes en cours de grossesse. Etiologie et moyens du diagnostic d’une thrombope´nie maternelle. In: le`re Journe´e parisienne obste´trico-pe´diatrique. Paris: Doin,: 49 - 53.
[19] Shamoon R. P., Muhammed N. S., and Jaff M. S. (2009). Prevalence and etiological classification of thrombocytopenia among a group of pregnant women in Erbil City, Iraq. Turk J. Hematol., 26: 123-128.
[20] Sullivan C. A., Martin J. N. Jr. (1995). Management of the obstetric patient with thrombocytopenia. Clin. Obstet. Gynecol., 38 (3): 521–534.
[21] Akinbami A. A., Ajibola S. O., Rabiu K. A., Adewunmi A. A., Dosunmu A. O., Adediran A., Osunkalu V. O,. Osikomaiya B. I. and Ismail K. A. (2013). Hematological profile of normal pregnant women in Lagos, Nigeria. Inter. J. Women Health, 5: 227-232.
[22] Parnas, M., Sheiner, E., Burstein, E., Shoham-Vardi, I,. Yermiahu, T., Levi, I., Holcberg, G., and Yerushalmi, R. (2006). Moderate to severe thrombocytopenia during pregnancy. Europ. J. Obstet. Gynecol. Reprod. Biol., 128: 163-168.
[23] Lee, L. H. (2002). Idiopathic thrombocytopenia in pregnancy. Ann. Acad. Med. Singapore, 3: 335 – 339.
[24] Memon AR, Afsar S. (2006). Thrombocytopenia in hospitalized malaria patients. Pak J Med Sci., 22: 141-143.
[25] Burrows, R. F., and Kelton, J. G. (1990). Thrombocytopenia at delivery. A prospective survey of 6715 deliveries. Am. J. Obstet. Gynecol., 162: 731–734.
[26] Ramsay M. (2010). Normal hematological changes during pregnancy and the puerperium. The obstetric hematology manual. Cambridge University Press, Cambridge, pp: 1–11.
[27] D’Angelo, A. (2007). 4A. 1 Thrombocytopenia in pregnancy. Thrombosis Res., 119 (1): S37-S38.
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  • APA Style

    Sumaya Elgodwi, Mustafa Lawar, Abdussattar Saadallah. (2021). Prevalence of Thrombocytopenia Among Pregnant Women in Tripoli Region /Libya. International Journal of Biomedical Science and Engineering, 9(4), 83-88. https://doi.org/10.11648/j.ijbse.20210904.12

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    ACS Style

    Sumaya Elgodwi; Mustafa Lawar; Abdussattar Saadallah. Prevalence of Thrombocytopenia Among Pregnant Women in Tripoli Region /Libya. Int. J. Biomed. Sci. Eng. 2021, 9(4), 83-88. doi: 10.11648/j.ijbse.20210904.12

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    AMA Style

    Sumaya Elgodwi, Mustafa Lawar, Abdussattar Saadallah. Prevalence of Thrombocytopenia Among Pregnant Women in Tripoli Region /Libya. Int J Biomed Sci Eng. 2021;9(4):83-88. doi: 10.11648/j.ijbse.20210904.12

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  • @article{10.11648/j.ijbse.20210904.12,
      author = {Sumaya Elgodwi and Mustafa Lawar and Abdussattar Saadallah},
      title = {Prevalence of Thrombocytopenia Among Pregnant Women in Tripoli Region /Libya},
      journal = {International Journal of Biomedical Science and Engineering},
      volume = {9},
      number = {4},
      pages = {83-88},
      doi = {10.11648/j.ijbse.20210904.12},
      url = {https://doi.org/10.11648/j.ijbse.20210904.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbse.20210904.12},
      abstract = {Thrombocytopenia is the definition of a condition in which the number of platelets is less than 150,000 / ml, and this deficiency may be the result of a lack of platelet production in the bone marrow or an increase in their breakdown in the connective tissue. This condition is common in pregnant women, with a global prevalence of about 7%. This study aims to find out the prevalence of this condition among pregnant women in the Tripoli area. A cross-sectional study design was used to assess the prevalence of thrombocytopenia among pregnant women who have visited the obstetrical ward department of obstetrics and gynecology in Al jalaa Hospital, Tripoli from January to April 2021. 1700 pregnant women have been included in the study during their follow-up in Al jalaa hospital of gynecology and obstetrics at the time of the study. 2 milliliters of venous blood were collected under aseptic conditions and transferred into (EDTA) tubes. The complete blood cell counts were determined using a Sysmex analyzer. Sony computer CORE i7 was used, bivariable statistical analysis was carried on using Microsoft office excel to evaluate the effect of an independent variable over the dependent variable. Results shows that 18% of pregnant women were thrombocytopenic; this thrombocytopenia was increased with age, upon the classification and severity of thrombocytopenia 78.5% were mild, and 21.5% were moderate thrombocytopenic with no sever cases. Conclusion: It can be concluded that thrombocytopenia disorders in pregnancy are very common in the Tripoli region, the prevalence of thrombocytopenia increased with the increase in the gestational age to reach the maximum at the third trimester of gestation.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Prevalence of Thrombocytopenia Among Pregnant Women in Tripoli Region /Libya
    AU  - Sumaya Elgodwi
    AU  - Mustafa Lawar
    AU  - Abdussattar Saadallah
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    DO  - 10.11648/j.ijbse.20210904.12
    T2  - International Journal of Biomedical Science and Engineering
    JF  - International Journal of Biomedical Science and Engineering
    JO  - International Journal of Biomedical Science and Engineering
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    EP  - 88
    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.ijbse.20210904.12
    AB  - Thrombocytopenia is the definition of a condition in which the number of platelets is less than 150,000 / ml, and this deficiency may be the result of a lack of platelet production in the bone marrow or an increase in their breakdown in the connective tissue. This condition is common in pregnant women, with a global prevalence of about 7%. This study aims to find out the prevalence of this condition among pregnant women in the Tripoli area. A cross-sectional study design was used to assess the prevalence of thrombocytopenia among pregnant women who have visited the obstetrical ward department of obstetrics and gynecology in Al jalaa Hospital, Tripoli from January to April 2021. 1700 pregnant women have been included in the study during their follow-up in Al jalaa hospital of gynecology and obstetrics at the time of the study. 2 milliliters of venous blood were collected under aseptic conditions and transferred into (EDTA) tubes. The complete blood cell counts were determined using a Sysmex analyzer. Sony computer CORE i7 was used, bivariable statistical analysis was carried on using Microsoft office excel to evaluate the effect of an independent variable over the dependent variable. Results shows that 18% of pregnant women were thrombocytopenic; this thrombocytopenia was increased with age, upon the classification and severity of thrombocytopenia 78.5% were mild, and 21.5% were moderate thrombocytopenic with no sever cases. Conclusion: It can be concluded that thrombocytopenia disorders in pregnancy are very common in the Tripoli region, the prevalence of thrombocytopenia increased with the increase in the gestational age to reach the maximum at the third trimester of gestation.
    VL  - 9
    IS  - 4
    ER  - 

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Author Information
  • Department of Medical Laboratories, Tripoli College of Medical Science Janzur, Tripoli, Libya

  • Department of Medical Laboratories, Higher Institute of Science and Medical Abusalim, Tripoli, Libya

  • Department of Medical Laboratories, Higher Institute of Science and Medical Abusalim, Tripoli, Libya

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