The occurrence of mycosis is relatively uncommon in healthy and immunocompetent hosts. But now a days, the incidence of fungal infections are increasing and there is no effective vaccine for fungal infections in contrast to bacterial and viral diseases. And also, available antifungal drugs are not effective to treat infected animals. Understanding the immunity against fungal infections is of interest which can contribute more for therapeutic and vaccine development. Therefore, this review focuses on the immune components involved in clearing fungal pathogens. Disease outcome is a result of host-pathogen interactions. Immunity is the body’s resistance to infection. Innate and acquired immune systems are involved to eliminate animal fungal infections. Innate immunity is not specific. It is the first line of defense, with genetically encoded receptors that identify greatly conserved pathogen-associated molecular patterns. Physical barriers, phagocytic cells, chemotactic factors and natural killer cells are some of the innate defense mechanisms. Adaptive immunity is specific. Lymphocytes have a unique and specific antigen receptor. It can be a humoral or cellular type of immune system. In adaptive immunity, there is a development of immunological memory in the host after exposure to a pathogen. However, there are no effective vaccines and antifungal drugs. So it causes high morbidity and mortality in animals and fungal pathogens have become a significant clinical challenge, leading to a global threat to controlling fungal infections. Therefore, good management of animals and treating concurrent infections strengthens their immunity. Besides, promoting research into fungal infections to develop new diagnostics, anti-fungal drugs and vaccines are recommended.
| Published in | Animal and Veterinary Sciences (Volume 10, Issue 2) |
| DOI | 10.11648/j.avs.20221002.11 |
| Page(s) | 15-20 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Fungi, Immunity, Infection, Mycosis
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APA Style
Dessie Abera. (2022). Review on Immunity to Fungal Infections in Animals. Animal and Veterinary Sciences, 10(2), 15-20. https://doi.org/10.11648/j.avs.20221002.11
ACS Style
Dessie Abera. Review on Immunity to Fungal Infections in Animals. Anim. Vet. Sci. 2022, 10(2), 15-20. doi: 10.11648/j.avs.20221002.11
AMA Style
Dessie Abera. Review on Immunity to Fungal Infections in Animals. Anim Vet Sci. 2022;10(2):15-20. doi: 10.11648/j.avs.20221002.11
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Download@article{10.11648/j.avs.20221002.11,
author = {Dessie Abera},
title = {Review on Immunity to Fungal Infections in Animals},
journal = {Animal and Veterinary Sciences},
volume = {10},
number = {2},
pages = {15-20},
doi = {10.11648/j.avs.20221002.11},
url = {https://doi.org/10.11648/j.avs.20221002.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20221002.11},
abstract = {The occurrence of mycosis is relatively uncommon in healthy and immunocompetent hosts. But now a days, the incidence of fungal infections are increasing and there is no effective vaccine for fungal infections in contrast to bacterial and viral diseases. And also, available antifungal drugs are not effective to treat infected animals. Understanding the immunity against fungal infections is of interest which can contribute more for therapeutic and vaccine development. Therefore, this review focuses on the immune components involved in clearing fungal pathogens. Disease outcome is a result of host-pathogen interactions. Immunity is the body’s resistance to infection. Innate and acquired immune systems are involved to eliminate animal fungal infections. Innate immunity is not specific. It is the first line of defense, with genetically encoded receptors that identify greatly conserved pathogen-associated molecular patterns. Physical barriers, phagocytic cells, chemotactic factors and natural killer cells are some of the innate defense mechanisms. Adaptive immunity is specific. Lymphocytes have a unique and specific antigen receptor. It can be a humoral or cellular type of immune system. In adaptive immunity, there is a development of immunological memory in the host after exposure to a pathogen. However, there are no effective vaccines and antifungal drugs. So it causes high morbidity and mortality in animals and fungal pathogens have become a significant clinical challenge, leading to a global threat to controlling fungal infections. Therefore, good management of animals and treating concurrent infections strengthens their immunity. Besides, promoting research into fungal infections to develop new diagnostics, anti-fungal drugs and vaccines are recommended.},
year = {2022}
}
TY - JOUR T1 - Review on Immunity to Fungal Infections in Animals AU - Dessie Abera Y1 - 2022/03/31 PY - 2022 N1 - https://doi.org/10.11648/j.avs.20221002.11 DO - 10.11648/j.avs.20221002.11 T2 - Animal and Veterinary Sciences JF - Animal and Veterinary Sciences JO - Animal and Veterinary Sciences SP - 15 EP - 20 PB - Science Publishing Group SN - 2328-5850 UR - https://doi.org/10.11648/j.avs.20221002.11 AB - The occurrence of mycosis is relatively uncommon in healthy and immunocompetent hosts. But now a days, the incidence of fungal infections are increasing and there is no effective vaccine for fungal infections in contrast to bacterial and viral diseases. And also, available antifungal drugs are not effective to treat infected animals. Understanding the immunity against fungal infections is of interest which can contribute more for therapeutic and vaccine development. Therefore, this review focuses on the immune components involved in clearing fungal pathogens. Disease outcome is a result of host-pathogen interactions. Immunity is the body’s resistance to infection. Innate and acquired immune systems are involved to eliminate animal fungal infections. Innate immunity is not specific. It is the first line of defense, with genetically encoded receptors that identify greatly conserved pathogen-associated molecular patterns. Physical barriers, phagocytic cells, chemotactic factors and natural killer cells are some of the innate defense mechanisms. Adaptive immunity is specific. Lymphocytes have a unique and specific antigen receptor. It can be a humoral or cellular type of immune system. In adaptive immunity, there is a development of immunological memory in the host after exposure to a pathogen. However, there are no effective vaccines and antifungal drugs. So it causes high morbidity and mortality in animals and fungal pathogens have become a significant clinical challenge, leading to a global threat to controlling fungal infections. Therefore, good management of animals and treating concurrent infections strengthens their immunity. Besides, promoting research into fungal infections to develop new diagnostics, anti-fungal drugs and vaccines are recommended. VL - 10 IS - 2 ER -
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