Traditionally Pterocarpus erinaceus stem bark have being widely used in treatment of anemia. The goal of this examination is to explore the viability of Pterocarpus erinaceus stem bark removes on jungle fever initiated paleness. Anaemia was induced by inoculation of 2ml of infected blood containing 0.1 x 107 Plasmodium beghei. The sickly mice were treated with 250 and 500mg/body weight of watery and ethanolic concentrates of Pterocarpus erinaceus stem bark for four days. The results shows that there is significant (P>0.005) increase in both haematological parameters (PCV, Hb and RBC), haematological indices (MCV, MCH and MCHC) and immunological parameters (WBC, platelets, neutrophils and lymphocytes) in malaria control compared to normal. Oral administration of 250 and 500mg/kg body weight of aqueous and ethanolic extract of Pterocarpus erinaceus stem bark shows significant increase (p>0.05) in haematological parameters compared to malaria control. There were significant improvement in WBC, platelets, neutrophils, hympolytes and MCH. Compared to malaria control. The anaemic mice treated with 250/500mg/kg body weight of ethanolic extract showed significant improvement in both haematological and immunological parameters tested. These result suggest that Pterocarpus erinaceus stem bark can he used in managing anemia.
| Published in | American Journal of Chemical and Biochemical Engineering (Volume 5, Issue 1) |
| DOI | 10.11648/j.ajcbe.20210501.13 |
| Page(s) | 21-25 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2021. Published by Science Publishing Group |
Pterocarpus erinaceus, Anaemia, Malaria
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APA Style
Ibrahim Mohammed, Hauwa’u Shuaibu Mohammed, Modibbo Abdullahi Abubakar. (2021). Effect of Pterocarpus erinaceus Stem Bark Extracts on Haematological Parameters in Malaria Induced Anaemic Mice. American Journal of Chemical and Biochemical Engineering, 5(1), 21-25. https://doi.org/10.11648/j.ajcbe.20210501.13
ACS Style
Ibrahim Mohammed; Hauwa’u Shuaibu Mohammed; Modibbo Abdullahi Abubakar. Effect of Pterocarpus erinaceus Stem Bark Extracts on Haematological Parameters in Malaria Induced Anaemic Mice. Am. J. Chem. Biochem. Eng. 2021, 5(1), 21-25. doi: 10.11648/j.ajcbe.20210501.13
AMA Style
Ibrahim Mohammed, Hauwa’u Shuaibu Mohammed, Modibbo Abdullahi Abubakar. Effect of Pterocarpus erinaceus Stem Bark Extracts on Haematological Parameters in Malaria Induced Anaemic Mice. Am J Chem Biochem Eng. 2021;5(1):21-25. doi: 10.11648/j.ajcbe.20210501.13
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Download@article{10.11648/j.ajcbe.20210501.13,
author = {Ibrahim Mohammed and Hauwa’u Shuaibu Mohammed and Modibbo Abdullahi Abubakar},
title = {Effect of Pterocarpus erinaceus Stem Bark Extracts on Haematological Parameters in Malaria Induced Anaemic Mice},
journal = {American Journal of Chemical and Biochemical Engineering},
volume = {5},
number = {1},
pages = {21-25},
doi = {10.11648/j.ajcbe.20210501.13},
url = {https://doi.org/10.11648/j.ajcbe.20210501.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcbe.20210501.13},
abstract = {Traditionally Pterocarpus erinaceus stem bark have being widely used in treatment of anemia. The goal of this examination is to explore the viability of Pterocarpus erinaceus stem bark removes on jungle fever initiated paleness. Anaemia was induced by inoculation of 2ml of infected blood containing 0.1 x 107 Plasmodium beghei. The sickly mice were treated with 250 and 500mg/body weight of watery and ethanolic concentrates of Pterocarpus erinaceus stem bark for four days. The results shows that there is significant (P>0.005) increase in both haematological parameters (PCV, Hb and RBC), haematological indices (MCV, MCH and MCHC) and immunological parameters (WBC, platelets, neutrophils and lymphocytes) in malaria control compared to normal. Oral administration of 250 and 500mg/kg body weight of aqueous and ethanolic extract of Pterocarpus erinaceus stem bark shows significant increase (p>0.05) in haematological parameters compared to malaria control. There were significant improvement in WBC, platelets, neutrophils, hympolytes and MCH. Compared to malaria control. The anaemic mice treated with 250/500mg/kg body weight of ethanolic extract showed significant improvement in both haematological and immunological parameters tested. These result suggest that Pterocarpus erinaceus stem bark can he used in managing anemia.},
year = {2021}
}
TY - JOUR T1 - Effect of Pterocarpus erinaceus Stem Bark Extracts on Haematological Parameters in Malaria Induced Anaemic Mice AU - Ibrahim Mohammed AU - Hauwa’u Shuaibu Mohammed AU - Modibbo Abdullahi Abubakar Y1 - 2021/04/16 PY - 2021 N1 - https://doi.org/10.11648/j.ajcbe.20210501.13 DO - 10.11648/j.ajcbe.20210501.13 T2 - American Journal of Chemical and Biochemical Engineering JF - American Journal of Chemical and Biochemical Engineering JO - American Journal of Chemical and Biochemical Engineering SP - 21 EP - 25 PB - Science Publishing Group SN - 2639-9989 UR - https://doi.org/10.11648/j.ajcbe.20210501.13 AB - Traditionally Pterocarpus erinaceus stem bark have being widely used in treatment of anemia. The goal of this examination is to explore the viability of Pterocarpus erinaceus stem bark removes on jungle fever initiated paleness. Anaemia was induced by inoculation of 2ml of infected blood containing 0.1 x 107 Plasmodium beghei. The sickly mice were treated with 250 and 500mg/body weight of watery and ethanolic concentrates of Pterocarpus erinaceus stem bark for four days. The results shows that there is significant (P>0.005) increase in both haematological parameters (PCV, Hb and RBC), haematological indices (MCV, MCH and MCHC) and immunological parameters (WBC, platelets, neutrophils and lymphocytes) in malaria control compared to normal. Oral administration of 250 and 500mg/kg body weight of aqueous and ethanolic extract of Pterocarpus erinaceus stem bark shows significant increase (p>0.05) in haematological parameters compared to malaria control. There were significant improvement in WBC, platelets, neutrophils, hympolytes and MCH. Compared to malaria control. The anaemic mice treated with 250/500mg/kg body weight of ethanolic extract showed significant improvement in both haematological and immunological parameters tested. These result suggest that Pterocarpus erinaceus stem bark can he used in managing anemia. VL - 5 IS - 1 ER -
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