Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level

Abdul Hakim; Mahmuder Rahman; Morium Begum

doi:doi:10.11648/j.ajbls.20210905.17

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Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level

Abdul Hakim, Mahmuder Rahman, Morium Begum

Published in American Journal of Biomedical and Life Sciences (Volume 9, Issue 5)

Received: 4 March 2021 Accepted: 2 August 2021 Published: 28 October 2021

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Abstract

Introduction: Perinatal asphyxia is one of the most common primary causes of mortality and morbidity among neonates. Perinatal asphyxia will result in neonatal hypoxia and tissue/organ injury. Objective: The aim of this study was to observe the Co-relation between Perinatal asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood sugar level. Methodology: This is a descriptive cross-sectional case study where a total of 182 neonates were admitted to the hospital with the problem of Perinatal asphyxia with Hypoxic Ischemic Encephalopathy and with some other associated problem. Result: Among the cases, 114 (62.6%) were Boys and 68 (37.45%) Girls. The mean age was 29.72 ± 78.42, Weight 2.77 ± .60, RBS 6.57 ± 7.38. Among the asphyxiated neonates blood sugar levels in arterial cord blood were significantly lower and had a negative (r=−0.195, P<0.01) correlation with the severity of birth asphyxia and different stages of HIE. Conclusion: Perinatal asphyxia can result in neonatal hypoxia and tissue/organ injury. A variety of maternal, obstetric, and neonatal conditions predispose the fetus and newborn to asphyxia, which can occur before, during, or after birth From our result, we can conclude that the relationship between Perinatal asphyxia and blood sugar level is significantly lower and negative.

Published in	American Journal of Biomedical and Life Sciences (Volume 9, Issue 5)
DOI	10.11648/j.ajbls.20210905.17
Page(s)	267-270
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Perinatal Asphyxia, Neonatal Hypoxia, Organ Injury

References

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[3]	Snyder EY, Cloherty JP (1998) perinatal asphyxia. In: Clohert JP, Stark AR (eds) Manual of neonatal care, 4th edn. Lippincott-Raven, Philadelphia, p 515–532.
[4]	Singh M (2004) Care of the baby in the labor room. In: Singh M(ed) Care of the newborn, 6th edn. Sagar Publications, New Delhi, p 107.
[5]	Jones MD Jr, Burd LI, Makowski EL, Meschia G, Battaglia FC (1975) cerebral metabolism in sheep: a comparative study of the adult, the lamb and the fetus. Am J Physiol 229: 235–239.
[6]	Volpe JJ (2000) Neurology of the newborn, 4th edn. WBSaunders, Philadelphia, pp 497–520.
[7]	Vannucci RC, Nardis EE, Vannucci SJ (1980) cerebral metabolism during hypoglycemia and asphyxia in newborn dogs. BiolNeonate 38: 276–286.
[8]	Erdag GC, Vitrinel A (2004) Can urinary uric acid/creatinine ratiobe used as an additional marker for neonatal asphyxia? Int Pediatr 19 (4): 217–219.
[9]	Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress: a clinical and electroencephalographics study. Arch Neural. 1976; 33 (10): 696-705.
[10]	Vannucci RC (1992) cerebral carbohydrate and energy metaboli smin perinatal hypoxic-ischemic brain damage. Brain Pathol 2: 229–234. doi: 10.1111/j.1750-3639.1992.tb00696.x
[11]	Anwar M, Vannucci RC (1988) Autoradiographic determination of regional cerebral blood flow during hypoglycemia in newborn dogs. Pediatr Res 24: 41–45. doi: 10.1203/00006450-198807000-00011.
[12]	Salhab WA, Wyckoff MH, Laptook AR, Perlman JM (2004) Initial hypoglycemia and neonatal brain injury in term infants with severe fetal acidemia. Pediatrics 114: 361–366. doi: 10.1542/ peds.114.2.36.
[13]	Basu P, Som S, Das H, Choudhuri B. Electrolyte status in birth asphyxia. Indian J Pediatr. 2010; 77 (3): 259-262.
[14]	Kavya, Rudrappa, S., & Gopal, G. (2020). Study and correlate the severity of birth asphyxia with serum levels of glucose, uric acid and electrolytes in the cord blood of asphyxiated neonates. International Journal of Contemporary Pediatrics, 8 (1), 98.
[15]	Aundhakar, C. D., & Bahatkar, K. (2021). Electrolyte status and plasma glucose levels in birth asphyxia: A case–control study. Journal of Medical Sciences (Taipei, Taiwan), 41 (1).

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APA Style

Abdul Hakim, Mahmuder Rahman, Morium Begum. (2021). Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level. American Journal of Biomedical and Life Sciences, 9(5), 267-270. https://doi.org/10.11648/j.ajbls.20210905.17

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ACS Style

Abdul Hakim; Mahmuder Rahman; Morium Begum. Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level. Am. J. Biomed. Life Sci. 2021, 9(5), 267-270. doi: 10.11648/j.ajbls.20210905.17

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AMA Style

Abdul Hakim, Mahmuder Rahman, Morium Begum. Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level. Am J Biomed Life Sci. 2021;9(5):267-270. doi: 10.11648/j.ajbls.20210905.17

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@article{10.11648/j.ajbls.20210905.17,
  author = {Abdul Hakim and Mahmuder Rahman and Morium Begum},
  title = {Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {9},
  number = {5},
  pages = {267-270},
  doi = {10.11648/j.ajbls.20210905.17},
  url = {https://doi.org/10.11648/j.ajbls.20210905.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20210905.17},
  abstract = {Introduction: Perinatal asphyxia is one of the most common primary causes of mortality and morbidity among neonates. Perinatal asphyxia will result in neonatal hypoxia and tissue/organ injury. Objective: The aim of this study was to observe the Co-relation between Perinatal asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood sugar level. Methodology: This is a descriptive cross-sectional case study where a total of 182 neonates were admitted to the hospital with the problem of Perinatal asphyxia with Hypoxic Ischemic Encephalopathy and with some other associated problem. Result: Among the cases, 114 (62.6%) were Boys and 68 (37.45%) Girls. The mean age was 29.72 ± 78.42, Weight 2.77 ± .60, RBS 6.57 ± 7.38. Among the asphyxiated neonates blood sugar levels in arterial cord blood were significantly lower and had a negative (r=−0.195, P<0.01) correlation with the severity of birth asphyxia and different stages of HIE. Conclusion: Perinatal asphyxia can result in neonatal hypoxia and tissue/organ injury. A variety of maternal, obstetric, and neonatal conditions predispose the fetus and newborn to asphyxia, which can occur before, during, or after birth From our result, we can conclude that the relationship between Perinatal asphyxia and blood sugar level is significantly lower and negative.},
 year = {2021}
}

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TY  - JOUR
T1  - Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level
AU  - Abdul Hakim
AU  - Mahmuder Rahman
AU  - Morium Begum
Y1  - 2021/10/28
PY  - 2021
N1  - https://doi.org/10.11648/j.ajbls.20210905.17
DO  - 10.11648/j.ajbls.20210905.17
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 267
EP  - 270
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20210905.17
AB  - Introduction: Perinatal asphyxia is one of the most common primary causes of mortality and morbidity among neonates. Perinatal asphyxia will result in neonatal hypoxia and tissue/organ injury. Objective: The aim of this study was to observe the Co-relation between Perinatal asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood sugar level. Methodology: This is a descriptive cross-sectional case study where a total of 182 neonates were admitted to the hospital with the problem of Perinatal asphyxia with Hypoxic Ischemic Encephalopathy and with some other associated problem. Result: Among the cases, 114 (62.6%) were Boys and 68 (37.45%) Girls. The mean age was 29.72 ± 78.42, Weight 2.77 ± .60, RBS 6.57 ± 7.38. Among the asphyxiated neonates blood sugar levels in arterial cord blood were significantly lower and had a negative (r=−0.195, P<0.01) correlation with the severity of birth asphyxia and different stages of HIE. Conclusion: Perinatal asphyxia can result in neonatal hypoxia and tissue/organ injury. A variety of maternal, obstetric, and neonatal conditions predispose the fetus and newborn to asphyxia, which can occur before, during, or after birth From our result, we can conclude that the relationship between Perinatal asphyxia and blood sugar level is significantly lower and negative.
VL  - 9
IS  - 5
ER  -

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Author Information

Abdul Hakim

Department of Pediatrics, Rangpur Medical College, Rangpur, Bangladesh
Mahmuder Rahman

Department of Pediatrics, Faridpur Medical College, Faridpur, Bangladesh
Morium Begum

Department of Obstetrics & Gynaecology, Rangpur Medical College Hospital, Rangpur, Bangladesh

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APA Style

Abdul Hakim, Mahmuder Rahman, Morium Begum. (2021). Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level. American Journal of Biomedical and Life Sciences, 9(5), 267-270. https://doi.org/10.11648/j.ajbls.20210905.17

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ACS Style

Abdul Hakim; Mahmuder Rahman; Morium Begum. Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level. Am. J. Biomed. Life Sci. 2021, 9(5), 267-270. doi: 10.11648/j.ajbls.20210905.17

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AMA Style

Abdul Hakim, Mahmuder Rahman, Morium Begum. Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level. Am J Biomed Life Sci. 2021;9(5):267-270. doi: 10.11648/j.ajbls.20210905.17

Copy | Download

@article{10.11648/j.ajbls.20210905.17,
  author = {Abdul Hakim and Mahmuder Rahman and Morium Begum},
  title = {Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {9},
  number = {5},
  pages = {267-270},
  doi = {10.11648/j.ajbls.20210905.17},
  url = {https://doi.org/10.11648/j.ajbls.20210905.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20210905.17},
  abstract = {Introduction: Perinatal asphyxia is one of the most common primary causes of mortality and morbidity among neonates. Perinatal asphyxia will result in neonatal hypoxia and tissue/organ injury. Objective: The aim of this study was to observe the Co-relation between Perinatal asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood sugar level. Methodology: This is a descriptive cross-sectional case study where a total of 182 neonates were admitted to the hospital with the problem of Perinatal asphyxia with Hypoxic Ischemic Encephalopathy and with some other associated problem. Result: Among the cases, 114 (62.6%) were Boys and 68 (37.45%) Girls. The mean age was 29.72 ± 78.42, Weight 2.77 ± .60, RBS 6.57 ± 7.38. Among the asphyxiated neonates blood sugar levels in arterial cord blood were significantly lower and had a negative (r=−0.195, P<0.01) correlation with the severity of birth asphyxia and different stages of HIE. Conclusion: Perinatal asphyxia can result in neonatal hypoxia and tissue/organ injury. A variety of maternal, obstetric, and neonatal conditions predispose the fetus and newborn to asphyxia, which can occur before, during, or after birth From our result, we can conclude that the relationship between Perinatal asphyxia and blood sugar level is significantly lower and negative.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level
AU  - Abdul Hakim
AU  - Mahmuder Rahman
AU  - Morium Begum
Y1  - 2021/10/28
PY  - 2021
N1  - https://doi.org/10.11648/j.ajbls.20210905.17
DO  - 10.11648/j.ajbls.20210905.17
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 267
EP  - 270
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20210905.17
AB  - Introduction: Perinatal asphyxia is one of the most common primary causes of mortality and morbidity among neonates. Perinatal asphyxia will result in neonatal hypoxia and tissue/organ injury. Objective: The aim of this study was to observe the Co-relation between Perinatal asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood sugar level. Methodology: This is a descriptive cross-sectional case study where a total of 182 neonates were admitted to the hospital with the problem of Perinatal asphyxia with Hypoxic Ischemic Encephalopathy and with some other associated problem. Result: Among the cases, 114 (62.6%) were Boys and 68 (37.45%) Girls. The mean age was 29.72 ± 78.42, Weight 2.77 ± .60, RBS 6.57 ± 7.38. Among the asphyxiated neonates blood sugar levels in arterial cord blood were significantly lower and had a negative (r=−0.195, P<0.01) correlation with the severity of birth asphyxia and different stages of HIE. Conclusion: Perinatal asphyxia can result in neonatal hypoxia and tissue/organ injury. A variety of maternal, obstetric, and neonatal conditions predispose the fetus and newborn to asphyxia, which can occur before, during, or after birth From our result, we can conclude that the relationship between Perinatal asphyxia and blood sugar level is significantly lower and negative.
VL  - 9
IS  - 5
ER  -

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