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The Place of X-ray Endovascular Catheter Technologies Taking into Account Errors in the Diagnostic and Treatment Algorithm of Patients with Mediastinal Tumors

Received: 26 September 2021    Accepted: 20 October 2021    Published: 30 October 2021
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Abstract

The purpose of the study. Increase the effectiveness of treatment of patients with epithelial tumors of the mediastinum by using intra-arterial chemoembolization as a neoadjuvant therapy to create ischemia and high concentrations of cytostatics in tumors for a long period of time to achieve devitalization of tumor tissue and reduce overall toxicity of chemotherapy. Object of study. Epithelial tumors of the thymus gland. Research methods: Clinical, laboratory, morphological, instrumental, statistical. Laboratory tests will include general clinical blood tests, biochemical parameters (ALT, AST, bilirubin, alkaline phosphatase, gammaglutamine transpeptidase, lactate dehydrogenase, albumin), biochemical markers of thymus tumor (AFP, HGT), acetylcholine. General blood test (hemoglobin, erythrocytes, leukocytes, platelets). Instrumental methods of examination will include CT (computed tomography) with intravenous contrast, MRI (magnetic resonance imaging). The conclusions can be made from the literature review. It can be stated that there is no common view on the diagnosis and choice of treatment tactics for patients with epithelial tumors of the thymus. Histological heterogeneity of tumors of this anatomical region with the similarity of clinical manifestations and radiological symptoms requires the development of algorithms for their differential diagnosis and optimization of treatment. In addition, over the last decade in Ukraine there has been a significant increase in the number of mediastinal tumors, especially the thymus gland. Given mainly the young age of patients with this disease and the high degree of aggressiveness of the disease, the problem is transformed to the social level. It is also necessary to review the traditional approach to the treatment of this pathology, the first link of which is considered to be surgery.

Published in American Journal of Biomedical and Life Sciences (Volume 9, Issue 5)
DOI 10.11648/j.ajbls.20210905.18
Page(s) 271-278
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Combination Treatment, Endovascular Technologies, Risk of Metastasis, Intra-arterial Chemoembolization, Regional (Selective) Chemotherapy, Thymoma Formation - Thymoma, Superior Vena Cava Syndrome

References
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    Kravchenko Roman Yuriyovych, Avdosyev Yuriy Volodymyrovych, Oleh Mykolayovych Luzan, Yakiv Ivanovych Ivashchik. (2021). The Place of X-ray Endovascular Catheter Technologies Taking into Account Errors in the Diagnostic and Treatment Algorithm of Patients with Mediastinal Tumors. American Journal of Biomedical and Life Sciences, 9(5), 271-278. https://doi.org/10.11648/j.ajbls.20210905.18

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    ACS Style

    Kravchenko Roman Yuriyovych; Avdosyev Yuriy Volodymyrovych; Oleh Mykolayovych Luzan; Yakiv Ivanovych Ivashchik. The Place of X-ray Endovascular Catheter Technologies Taking into Account Errors in the Diagnostic and Treatment Algorithm of Patients with Mediastinal Tumors. Am. J. Biomed. Life Sci. 2021, 9(5), 271-278. doi: 10.11648/j.ajbls.20210905.18

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    AMA Style

    Kravchenko Roman Yuriyovych, Avdosyev Yuriy Volodymyrovych, Oleh Mykolayovych Luzan, Yakiv Ivanovych Ivashchik. The Place of X-ray Endovascular Catheter Technologies Taking into Account Errors in the Diagnostic and Treatment Algorithm of Patients with Mediastinal Tumors. Am J Biomed Life Sci. 2021;9(5):271-278. doi: 10.11648/j.ajbls.20210905.18

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  • @article{10.11648/j.ajbls.20210905.18,
      author = {Kravchenko Roman Yuriyovych and Avdosyev Yuriy Volodymyrovych and Oleh Mykolayovych Luzan and Yakiv Ivanovych Ivashchik},
      title = {The Place of X-ray Endovascular Catheter Technologies Taking into Account Errors in the Diagnostic and Treatment Algorithm of Patients with Mediastinal Tumors},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {9},
      number = {5},
      pages = {271-278},
      doi = {10.11648/j.ajbls.20210905.18},
      url = {https://doi.org/10.11648/j.ajbls.20210905.18},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20210905.18},
      abstract = {The purpose of the study. Increase the effectiveness of treatment of patients with epithelial tumors of the mediastinum by using intra-arterial chemoembolization as a neoadjuvant therapy to create ischemia and high concentrations of cytostatics in tumors for a long period of time to achieve devitalization of tumor tissue and reduce overall toxicity of chemotherapy. Object of study. Epithelial tumors of the thymus gland. Research methods: Clinical, laboratory, morphological, instrumental, statistical. Laboratory tests will include general clinical blood tests, biochemical parameters (ALT, AST, bilirubin, alkaline phosphatase, gammaglutamine transpeptidase, lactate dehydrogenase, albumin), biochemical markers of thymus tumor (AFP, HGT), acetylcholine. General blood test (hemoglobin, erythrocytes, leukocytes, platelets). Instrumental methods of examination will include CT (computed tomography) with intravenous contrast, MRI (magnetic resonance imaging). The conclusions can be made from the literature review. It can be stated that there is no common view on the diagnosis and choice of treatment tactics for patients with epithelial tumors of the thymus. Histological heterogeneity of tumors of this anatomical region with the similarity of clinical manifestations and radiological symptoms requires the development of algorithms for their differential diagnosis and optimization of treatment. In addition, over the last decade in Ukraine there has been a significant increase in the number of mediastinal tumors, especially the thymus gland. Given mainly the young age of patients with this disease and the high degree of aggressiveness of the disease, the problem is transformed to the social level. It is also necessary to review the traditional approach to the treatment of this pathology, the first link of which is considered to be surgery.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - The Place of X-ray Endovascular Catheter Technologies Taking into Account Errors in the Diagnostic and Treatment Algorithm of Patients with Mediastinal Tumors
    AU  - Kravchenko Roman Yuriyovych
    AU  - Avdosyev Yuriy Volodymyrovych
    AU  - Oleh Mykolayovych Luzan
    AU  - Yakiv Ivanovych Ivashchik
    Y1  - 2021/10/30
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ajbls.20210905.18
    DO  - 10.11648/j.ajbls.20210905.18
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 271
    EP  - 278
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.20210905.18
    AB  - The purpose of the study. Increase the effectiveness of treatment of patients with epithelial tumors of the mediastinum by using intra-arterial chemoembolization as a neoadjuvant therapy to create ischemia and high concentrations of cytostatics in tumors for a long period of time to achieve devitalization of tumor tissue and reduce overall toxicity of chemotherapy. Object of study. Epithelial tumors of the thymus gland. Research methods: Clinical, laboratory, morphological, instrumental, statistical. Laboratory tests will include general clinical blood tests, biochemical parameters (ALT, AST, bilirubin, alkaline phosphatase, gammaglutamine transpeptidase, lactate dehydrogenase, albumin), biochemical markers of thymus tumor (AFP, HGT), acetylcholine. General blood test (hemoglobin, erythrocytes, leukocytes, platelets). Instrumental methods of examination will include CT (computed tomography) with intravenous contrast, MRI (magnetic resonance imaging). The conclusions can be made from the literature review. It can be stated that there is no common view on the diagnosis and choice of treatment tactics for patients with epithelial tumors of the thymus. Histological heterogeneity of tumors of this anatomical region with the similarity of clinical manifestations and radiological symptoms requires the development of algorithms for their differential diagnosis and optimization of treatment. In addition, over the last decade in Ukraine there has been a significant increase in the number of mediastinal tumors, especially the thymus gland. Given mainly the young age of patients with this disease and the high degree of aggressiveness of the disease, the problem is transformed to the social level. It is also necessary to review the traditional approach to the treatment of this pathology, the first link of which is considered to be surgery.
    VL  - 9
    IS  - 5
    ER  - 

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Author Information
  • Department of Oncology and Pediatric Oncology of KhMAPE, Chernihiv Regional Hospital, Chernihiv, Ukraine

  • Department of Oncology and Pediatric Oncology of KhMAPE, Chernihiv Regional Hospital, Chernihiv, Ukraine

  • The Surgical Thoracic Department, Chernihiv Regional Hospital, Chernihiv, Ukraine

  • The Surgical Thoracic Department, Chernihiv Regional Hospital, Chernihiv, Ukraine

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