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Investigation of Levels of Some Selected Heavy Metals in Raw Bovine Milk from Oyam District, Uganda and Estimation of Potential Health Risks

Received: 21 October 2021    Accepted: 8 November 2021    Published: 28 January 2022
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Abstract

Heavy metal contamination is a serious threat because of their toxicity, bio-magnification and bioaccumulation in food chain. The deficiency of some of these metal elements leads to impairment of vital biological process but when they are present in excess, they become toxic. Raw bovine milk is considered as one of the food sources contaminated with heavy metals, because cows graze on the grass grown in lands which somehow come in contact with the untreated effluent of industries. Milk is a very important component of human diet. The present study was aimed at investigating the levels of selected heavy metals (Cr, Cd, and Pb) in raw bovine milk produced in Oyam District, Uganda and estimation of potential health risks associated with long term exposure to heavy metal contaminated milk from the said area. Experimental results indicated that the mean concentration levels of the metals were 0.17±0.08, 6.84±2.03 and 0.13±0.05 ppm for Lead, Chromium and Cadmium, respectively for all samples taken from Aber Sub County. The mean concentration levels of the metals were 0.15±0.07, 6.55±1.71 and 0.12±0.04 ppm for Lead, Chromium and Cadmium, respectively, for samples taken from Acaba Sub County. The mean concentration levels of the metals were 0.16±0.07, 6.83±1.74 and 0.15±0.11 ppm for Lead, Chromium and Cadmium, respectively, for samples taken from Loro Sub County. The mean concentration levels of the metals were 0.28±0.18, 8.34±2.92 and 0.19±0.13 ppm for Lead, Chromium and Cadmium, respectively, for samples taken from Kamdini Sub County. The Target Hazard Quotient (THQ) of all heavy metals analyzed (Pb, Cr and Cd) in milk samples was found to be less than 1. Hence it would be inferred that it’s safe to drink the milk from this area.

Published in American Journal of Applied and Industrial Chemistry (Volume 6, Issue 1)
DOI 10.11648/j.ajaic.20220601.11
Page(s) 1-6
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Lead, Cadmium, Chromium, Bovine Milk, Heavy Metals, Oyam District, Health Risks

References
[1] Van Winckel, M., Velde, Sv., De Bruyne, R., Van Bierviet, S “Clincal Practices” European Journal Of Pedraatics 170 (12), 2011: 1489-1494.
[2] Farid, S. M., M. A. Enani, and S. A. Wajid. “Determination of trace elements in cow milk in Saudi Aribia.” Egn. Sci. Volume 15 (0-2), 2004: 131-140.
[3] Meshref, A., Moselhy, W “Heavy metals and trace elements in milk and milk products” Journal of Food measurements and charcterisation, 2014.
[4] Barłowska, M. Szwajkowska, Z. Litwi´nczuk, and J. Kr´o,. (2011). Nutritional Value and Technological Suitability of Milk from Various Animal Species Used for Dairy Production. Comprehensive Reviews in Food Science and Food Safety Vol. 10, 291-302.
[5] Fox, P. F. Advance Dairy Chemistry, Vol. 3: Lactose, Water, Salts and Vitamins. 2nd Ed. Chapman and Hall: New York, 1995.
[6] A. A. Jigam, E. N. Dauda, T. Jimoh, N. H. Yusuf and Z. T. Umar. “Determination of copper, zinc, lead and some biochemical parameters in fresh cow milk from different locations in Niger state, Nigeia.” Journal of food science 5 (3), 2011: 156-160.
[7] Renata Pilarczyk, Jerzy Wójcik, PawełCzerniak, Piotr Sablik, Bogumiła Pilarczyk, Agnieszka Tomza-Marciniak "Concentrations of toxic heavy metals and trace elements in raw milk of Simmental and Holstein-Friesian cows from organic farm" Environmental monitoring and assessment 185 (10), 8383-8392, 2013.
[8] Ahmed Hussen Tassew Belete, Vegi Maheswara Rao "Determination of concentrations of selected heavy metals in cow’s milk: Borena zone, Ethiopia" Journal of Health Science 4 (5), 105, 2014.
[9] Naithani, V., N. Pathak, M. Chaudhary. “Evaluation of Heavy Metals in Two Major Ingredients of Ampucare.” International Journal of Pharmaceutical Sciences and Drug Research. 2, 2010: 137-141.
[10] Mingorance, M. D., 2002, Focused microwave-assisted digestion of vegetal materials for the determination of essential mineral nutrients., Anal Bioanal Chem., 373, 153158.
[11] Arain, M. Kazi, T. G., Jamali, M. K., Afridi, H. I., Jalbani, N., Memon, A. R., 2007, Ultrasound-assisted pseudodigestion for toxic metals determination in fish muscles followed by electro thermal atomic absorption spectrophotometry: multivariate strategy., J AOAC Int., 90, 1118-1127.
[12] Shah, A, Q., Kazi, T. G., Arain, M. b., Jamali, M. K., Afridi, H, I., Jalbani, N., J. A., Sarfraz, R. A., Ansari, R, 2009, Comparison of electro thermal and hydride generation atomic absorption spectrometry for the determination of total arsenic in broiler chicken., food Chem., 113, 1351-1355.
[13] Jalbani, N., Kazi, T. G., Jamali, M. K., Arain, B. M., Afridi, H. I., Baloch, A., 2007, Evaluation of aluminum contents in different bakery foods by electrothermal atomic absorption spectrometer., J Food Compos Anal., 20, 226-231.
[14] Demirel, S., Tuzen, M., Saracoglu, S., Soyiak, M., 2008, Evaluation of various digestion procedures for trace element contents of some food materials., J Hazard Mater., 152, 1020-1026.
[15] Soyeurt, H., Bruwier, D., Romnee, J. M., Gengler, N., Bertozzi, C., Veselko, D., Dardenne, P., 2009, Potential estimation of major mineral contents in cow milk using midinfrared spectrometry., J Dairy Sci., 92, 2444-2454.
[16] Ehling, S., Tefera, S., Earl, R., Cole, S., 2010, Comparison of analytical methods to determine sodium content of lowsodium foods., J AOAC Int., 93, 628-637.
[17] Ogabiela E. E., Udiba, U. U., Adesina, O. B., Hammuel, C., Ade-Ajayi, F. A., Yebpella, G. G., Mmereole U. J., Abdullahi, M., 2011, Assessment of metal levels in fresh milk from cows grazed around Challawa Industrial Estate of Kano, Nigeria., J Basic ApplSci Res., 1 (7), 533-538.
[18] Abd-El Aal, S. F. A., A wad, E. I., Kamal, R. M. K. M., 2012, Prevalence of some trace and toxic elements in raw and sterilized cow's milk., J Am S ci., 8 (9), 753-761.
[19] Starka, K., Wojciechowska-Mazurek, M., Mania, M., Brulinska-Ostrowska, E., Biernat, U., Karlowski, K., 2011, Noxious elements in milk and milk products in Poland., polish J of Environ Stud., 20 (4), 1043-1051.
[20] Munoz, E., and Palmero, S., 2004, Determination of heavy metals in milk by potentiometric stripping analysis using a home-made flow cell., Food Control., 15, 635-641.
[21] Masotti, F., Erba, D., De Noni, I., Pellegrino, L., 2012, Rapid determination of sodium in milk and milk products by capillary zone electrophoresis., J Dairy Sci., 95, 2812-2881.
[22] Tripathi, R. M., Raghunath, R., Sastry, V. N., Krishnamoorthy, T. M., 1999, Daily intake of heavy metals by infants through milk and milk products., Sci Total Environ., 227, 9. 229-235.
[23] Sola-Larranaga, C., and Navarro-Blasco, I., 2009, Chemometric analysis of minerals and trace elements in raw cow milk from the community of Navarra, Spain., Food Chem., 112, 189-196.
[24] Solis, C., Isaac-Olive, K., Mireles, A., Vidal-Hernandez., M., 2009, Determination of trace metals in cow' s milk from waste water irrigated areas in Central Mexico by chemical treatment coupled to PIXE., Microchem J., 91, 9-12.
[25] Hussain, Z., Nazir, A., Shafique, U., Salmen, M., 2010, Comparative study for the determination of metals in milk samples using flame-AAS and EDTA complexometric titration., J Sci RES,., 2 (1), 9-14.
[26] Sikiric, M., B rajenovic, N., Pavlovic, I., Havranek, J. L, plavljanic, N., 2003, Determination of metals in cow, s milk by flame atomic absorption spectrophotometry., Czech J Anim Sci., 48 (11), 481-486.
[27] Tajkarimi, M., M,. Ahmadifaghih, M., poursoltani, H., Salah Nejad, A., Motallebi, A, A., Mahdavi, H,. 2008, lead residue levels in raw milk from different regions of lran, nFood Control., 19, 495-498.
[28] Amir, I., Riaz, M., Saeed, A., Tariq, I., Zulfiqar, A., Saad, M. H., 2015 “Estimated daily intake and health risk of heavy metals by comsumption of milk”. Food additives and contaminants: part B surveillance 8 (4).
[29] Muhib, M. I., Chowdhury, M. A. Z., Easha, N. J., Rahman, M. M., Shammi, M., Fardous, Z., Bari, M. L., Uddin, M. K., Kurasaki, M., “Investigation of heavy metal contents in cow milk samples from area of Dhaka, Bangladesh”. International journal of food contamination (2016) 3: 16.
[30] Abdus-Salam, N. And Adekola, F. A “The Influence of Ph and Adsorption of Lead And Zinc on A Natural Goethite”. African Journal of Science and Technology (Ajst), Science And Engineering Series Vol. 6, No. 2, Pp. 55-66.
[31] Tripathi, R. M.; Raghunath, R. and Krishnamoorthy, T. M., Dietary intake of heavy metals in Bombay city, India, Sci. of Total Environ, 208: 49-159 (1997).
[32] Krishnamoorty. T. M, and tripathi, R. M., measurements and modeling in environmental pollution BARC news letterindia 179; 3-12 (1998).
[33] SEHUHMACHER, M., domingo, jl. And corbella. j. dietary intake of copper. Chromium and zinc in Tarragona province spainsci of total environ., 132; 3-10 (1983).
[34] Bulinski, r., bloniarz, j. and libel, B., trace element content in milk and some milk products. bromate. chemtoksykol., xxv; 327-331 (1992).
[35] Lopez., A., Collins., w. f. and Williams, H. L. essential elements in raw and pasteurized cow and goat milk, j. dairy sci., 68; 1878-1886 (1995).
[36] M. Dakiky, M. Khamis, A. Manassra, and M. Mer’eb, “Selective Adsorption of Chromium (VI) in Industrial Wastewater Using Low-Cost Abundantly Available Adsorbents,” Advances in Environmental Research, vol. 6, pp. 533–540, Oct. 2002, doi: 10.1016/S1093-0191(01)00079-X.
[37] R. A. Bernhoft, “Cadmium Toxicity and Treatment,” The Scientific World Journal, vol. 2013, p. 394652, 2013, doi: 10.1155/2013/394652.
[38] H. Ali, E. Khan, and I. Ilahi, “Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation,” Journal of Chemistry, vol. 2019, p. 6730305, 2019, doi: 10.1155/2019/6730305.
[39] J. Briffa, E. Sinagra, and R. Blundell, “Heavy metal pollution in the environment and their toxicological effects on humans,” Heliyon, vol. 6, no. 9. Elsevier Ltd, Sep. 01, 2020. doi: 10.1016/j.heliyon.2020.e04691.
[40] L. Järup, “Hazards of heavy metal contamination,” British Medical Bulletin, vol. 68. pp. 167–182, 2003. doi: 10.1093/bmb/ldg032.
Cite This Article
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    Mike Odongo, Solomon Alex Mutagaya, William Wanasolo, Dominic Oketch. (2022). Investigation of Levels of Some Selected Heavy Metals in Raw Bovine Milk from Oyam District, Uganda and Estimation of Potential Health Risks. American Journal of Applied and Industrial Chemistry, 6(1), 1-6. https://doi.org/10.11648/j.ajaic.20220601.11

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    ACS Style

    Mike Odongo; Solomon Alex Mutagaya; William Wanasolo; Dominic Oketch. Investigation of Levels of Some Selected Heavy Metals in Raw Bovine Milk from Oyam District, Uganda and Estimation of Potential Health Risks. Am. J. Appl. Ind. Chem. 2022, 6(1), 1-6. doi: 10.11648/j.ajaic.20220601.11

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    AMA Style

    Mike Odongo, Solomon Alex Mutagaya, William Wanasolo, Dominic Oketch. Investigation of Levels of Some Selected Heavy Metals in Raw Bovine Milk from Oyam District, Uganda and Estimation of Potential Health Risks. Am J Appl Ind Chem. 2022;6(1):1-6. doi: 10.11648/j.ajaic.20220601.11

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  • @article{10.11648/j.ajaic.20220601.11,
      author = {Mike Odongo and Solomon Alex Mutagaya and William Wanasolo and Dominic Oketch},
      title = {Investigation of Levels of Some Selected Heavy Metals in Raw Bovine Milk from Oyam District, Uganda and Estimation of Potential Health Risks},
      journal = {American Journal of Applied and Industrial Chemistry},
      volume = {6},
      number = {1},
      pages = {1-6},
      doi = {10.11648/j.ajaic.20220601.11},
      url = {https://doi.org/10.11648/j.ajaic.20220601.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajaic.20220601.11},
      abstract = {Heavy metal contamination is a serious threat because of their toxicity, bio-magnification and bioaccumulation in food chain. The deficiency of some of these metal elements leads to impairment of vital biological process but when they are present in excess, they become toxic. Raw bovine milk is considered as one of the food sources contaminated with heavy metals, because cows graze on the grass grown in lands which somehow come in contact with the untreated effluent of industries. Milk is a very important component of human diet. The present study was aimed at investigating the levels of selected heavy metals (Cr, Cd, and Pb) in raw bovine milk produced in Oyam District, Uganda and estimation of potential health risks associated with long term exposure to heavy metal contaminated milk from the said area. Experimental results indicated that the mean concentration levels of the metals were 0.17±0.08, 6.84±2.03 and 0.13±0.05 ppm for Lead, Chromium and Cadmium, respectively for all samples taken from Aber Sub County. The mean concentration levels of the metals were 0.15±0.07, 6.55±1.71 and 0.12±0.04 ppm for Lead, Chromium and Cadmium, respectively, for samples taken from Acaba Sub County. The mean concentration levels of the metals were 0.16±0.07, 6.83±1.74 and 0.15±0.11 ppm for Lead, Chromium and Cadmium, respectively, for samples taken from Loro Sub County. The mean concentration levels of the metals were 0.28±0.18, 8.34±2.92 and 0.19±0.13 ppm for Lead, Chromium and Cadmium, respectively, for samples taken from Kamdini Sub County. The Target Hazard Quotient (THQ) of all heavy metals analyzed (Pb, Cr and Cd) in milk samples was found to be less than 1. Hence it would be inferred that it’s safe to drink the milk from this area.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Investigation of Levels of Some Selected Heavy Metals in Raw Bovine Milk from Oyam District, Uganda and Estimation of Potential Health Risks
    AU  - Mike Odongo
    AU  - Solomon Alex Mutagaya
    AU  - William Wanasolo
    AU  - Dominic Oketch
    Y1  - 2022/01/28
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ajaic.20220601.11
    DO  - 10.11648/j.ajaic.20220601.11
    T2  - American Journal of Applied and Industrial Chemistry
    JF  - American Journal of Applied and Industrial Chemistry
    JO  - American Journal of Applied and Industrial Chemistry
    SP  - 1
    EP  - 6
    PB  - Science Publishing Group
    SN  - 2994-7294
    UR  - https://doi.org/10.11648/j.ajaic.20220601.11
    AB  - Heavy metal contamination is a serious threat because of their toxicity, bio-magnification and bioaccumulation in food chain. The deficiency of some of these metal elements leads to impairment of vital biological process but when they are present in excess, they become toxic. Raw bovine milk is considered as one of the food sources contaminated with heavy metals, because cows graze on the grass grown in lands which somehow come in contact with the untreated effluent of industries. Milk is a very important component of human diet. The present study was aimed at investigating the levels of selected heavy metals (Cr, Cd, and Pb) in raw bovine milk produced in Oyam District, Uganda and estimation of potential health risks associated with long term exposure to heavy metal contaminated milk from the said area. Experimental results indicated that the mean concentration levels of the metals were 0.17±0.08, 6.84±2.03 and 0.13±0.05 ppm for Lead, Chromium and Cadmium, respectively for all samples taken from Aber Sub County. The mean concentration levels of the metals were 0.15±0.07, 6.55±1.71 and 0.12±0.04 ppm for Lead, Chromium and Cadmium, respectively, for samples taken from Acaba Sub County. The mean concentration levels of the metals were 0.16±0.07, 6.83±1.74 and 0.15±0.11 ppm for Lead, Chromium and Cadmium, respectively, for samples taken from Loro Sub County. The mean concentration levels of the metals were 0.28±0.18, 8.34±2.92 and 0.19±0.13 ppm for Lead, Chromium and Cadmium, respectively, for samples taken from Kamdini Sub County. The Target Hazard Quotient (THQ) of all heavy metals analyzed (Pb, Cr and Cd) in milk samples was found to be less than 1. Hence it would be inferred that it’s safe to drink the milk from this area.
    VL  - 6
    IS  - 1
    ER  - 

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Author Information
  • Department of Chemistry, Kyambogo University, Kampala, Uganda

  • Department of Chemistry, Kyambogo University, Kampala, Uganda

  • Department of Chemistry, Kyambogo University, Kampala, Uganda

  • Department of Chemistry, Kyambogo University, Kampala, Uganda

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