,
Jessica Brown
Background: The rapidly acting opioid fentanyl, commonly used in the perioperative setting, has traditionally been packaged in 100 or 250-μg vials. In September 2021, our institution implemented a change from fentanyl 100-μg vials to 50-μg preloaded syringes in our operating rooms. The objective of this study was aimed at assessing the association of the fentanyl product change on reducing medication waste and the amount of fentanyl administered during surgery. Methods: This single-center, retrospective study entailed a review of anesthesia records from September 2020 to September 2022 of adult patients who underwent general anesthesia and received fentanyl for surgery at The University of Texas MD Anderson Cancer Center. The data set was divided into a control period (CP) using 100-μg vials and a post transition period (PT) using 50-μg preloaded syringes. The primary outcome measures were the average amounts of fentanyl used and wasted per case. Secondary outcome measures consisted of intraoperative analgesic use as well as postoperative pain scores. Results: Among the 33,405 cases included in this study, the mean amount of fentanyl used per surgical case was higher in the CP group than in the PT group (133μg vs. 102μg; p<0.001). Additionally, fentanyl waste occurred in a higher percentage of cases in the CP group than in the PT group (13.9% vs. 2.9%; p<0.001). We did not observe a significant difference in post-anesthesia care unit pain scores between the CP and PT groups. Conclusion: Transitioning to preloaded fentanyl syringes decreased medication waste and overuse of opioids intraoperatively. Simultaneously, the transition did not adversely affect patient analgesia in the post-anesthesia care unit.
| Published in | International Journal of Anesthesia and Clinical Medicine (Volume 12, Issue 2) |
| DOI | 10.11648/j.ijacm.20241202.18 |
| Page(s) | 109-115 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Opioids, Waste, Medication Vial Size, Preloaded Syringe, Analgesia
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APA Style
Huang, H., Lai, E., Bhavsar, S., Miller, B., Chung, J., et al. (2024). Comparison of Intraoperative Fentanyl Usage and Waste After Transition from 100-μg Vials to 50-μg Preloaded Syringes: A Single-Center Retrospective Study. International Journal of Anesthesia and Clinical Medicine, 12(2), 109-115. https://doi.org/10.11648/j.ijacm.20241202.18
ACS Style
Huang, H.; Lai, E.; Bhavsar, S.; Miller, B.; Chung, J., et al. Comparison of Intraoperative Fentanyl Usage and Waste After Transition from 100-μg Vials to 50-μg Preloaded Syringes: A Single-Center Retrospective Study. Int. J. Anesth. Clin. Med. 2024, 12(2), 109-115. doi: 10.11648/j.ijacm.20241202.18
AMA Style
Huang H, Lai E, Bhavsar S, Miller B, Chung J, et al. Comparison of Intraoperative Fentanyl Usage and Waste After Transition from 100-μg Vials to 50-μg Preloaded Syringes: A Single-Center Retrospective Study. Int J Anesth Clin Med. 2024;12(2):109-115. doi: 10.11648/j.ijacm.20241202.18
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Download@article{10.11648/j.ijacm.20241202.18,
author = {Huang Huang and Emily Lai and Shreyas Bhavsar and Brian Miller and Jovelle Chung and Bradly Phillips and Lei Feng and Jose Miguel Soliz and Jessica Brown},
title = {Comparison of Intraoperative Fentanyl Usage and Waste After Transition from 100-μg Vials to 50-μg Preloaded Syringes: A Single-Center Retrospective Study
},
journal = {International Journal of Anesthesia and Clinical Medicine},
volume = {12},
number = {2},
pages = {109-115},
doi = {10.11648/j.ijacm.20241202.18},
url = {https://doi.org/10.11648/j.ijacm.20241202.18},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijacm.20241202.18},
abstract = {Background: The rapidly acting opioid fentanyl, commonly used in the perioperative setting, has traditionally been packaged in 100 or 250-μg vials. In September 2021, our institution implemented a change from fentanyl 100-μg vials to 50-μg preloaded syringes in our operating rooms. The objective of this study was aimed at assessing the association of the fentanyl product change on reducing medication waste and the amount of fentanyl administered during surgery. Methods: This single-center, retrospective study entailed a review of anesthesia records from September 2020 to September 2022 of adult patients who underwent general anesthesia and received fentanyl for surgery at The University of Texas MD Anderson Cancer Center. The data set was divided into a control period (CP) using 100-μg vials and a post transition period (PT) using 50-μg preloaded syringes. The primary outcome measures were the average amounts of fentanyl used and wasted per case. Secondary outcome measures consisted of intraoperative analgesic use as well as postoperative pain scores. Results: Among the 33,405 cases included in this study, the mean amount of fentanyl used per surgical case was higher in the CP group than in the PT group (133μg vs. 102μg; p<0.001). Additionally, fentanyl waste occurred in a higher percentage of cases in the CP group than in the PT group (13.9% vs. 2.9%; p<0.001). We did not observe a significant difference in post-anesthesia care unit pain scores between the CP and PT groups. Conclusion: Transitioning to preloaded fentanyl syringes decreased medication waste and overuse of opioids intraoperatively. Simultaneously, the transition did not adversely affect patient analgesia in the post-anesthesia care unit.
},
year = {2024}
}
TY - JOUR T1 - Comparison of Intraoperative Fentanyl Usage and Waste After Transition from 100-μg Vials to 50-μg Preloaded Syringes: A Single-Center Retrospective Study AU - Huang Huang AU - Emily Lai AU - Shreyas Bhavsar AU - Brian Miller AU - Jovelle Chung AU - Bradly Phillips AU - Lei Feng AU - Jose Miguel Soliz AU - Jessica Brown Y1 - 2024/11/22 PY - 2024 N1 - https://doi.org/10.11648/j.ijacm.20241202.18 DO - 10.11648/j.ijacm.20241202.18 T2 - International Journal of Anesthesia and Clinical Medicine JF - International Journal of Anesthesia and Clinical Medicine JO - International Journal of Anesthesia and Clinical Medicine SP - 109 EP - 115 PB - Science Publishing Group SN - 2997-2698 UR - https://doi.org/10.11648/j.ijacm.20241202.18 AB - Background: The rapidly acting opioid fentanyl, commonly used in the perioperative setting, has traditionally been packaged in 100 or 250-μg vials. In September 2021, our institution implemented a change from fentanyl 100-μg vials to 50-μg preloaded syringes in our operating rooms. The objective of this study was aimed at assessing the association of the fentanyl product change on reducing medication waste and the amount of fentanyl administered during surgery. Methods: This single-center, retrospective study entailed a review of anesthesia records from September 2020 to September 2022 of adult patients who underwent general anesthesia and received fentanyl for surgery at The University of Texas MD Anderson Cancer Center. The data set was divided into a control period (CP) using 100-μg vials and a post transition period (PT) using 50-μg preloaded syringes. The primary outcome measures were the average amounts of fentanyl used and wasted per case. Secondary outcome measures consisted of intraoperative analgesic use as well as postoperative pain scores. Results: Among the 33,405 cases included in this study, the mean amount of fentanyl used per surgical case was higher in the CP group than in the PT group (133μg vs. 102μg; p<0.001). Additionally, fentanyl waste occurred in a higher percentage of cases in the CP group than in the PT group (13.9% vs. 2.9%; p<0.001). We did not observe a significant difference in post-anesthesia care unit pain scores between the CP and PT groups. Conclusion: Transitioning to preloaded fentanyl syringes decreased medication waste and overuse of opioids intraoperatively. Simultaneously, the transition did not adversely affect patient analgesia in the post-anesthesia care unit. VL - 12 IS - 2 ER -
Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA
Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA
Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA
Department of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, USA
Department of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, USA
Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA
Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, USA
Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA
Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA
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