Retrospective Analysis of Bacterial Pathogens Isolated from Wound Infections at a Tertiary Hospital in Nguru, Yobe State Nigeria
American Journal of Biomedical and Life Sciences
Volume 3, Issue 1, February 2015, Pages: 1-6
Received: Mar. 6, 2015;
Accepted: Mar. 20, 2015;
Published: Mar. 24, 2015
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Bularafa Mohammed Yasidi, Department of Medical Microbiology, Federal Medical Centre, Nguru, Nigeria
Denue Ballah Akawu, Department of Medicine, University of Maiduguri Teaching Hospital, Maiduguri,Nigeria
Onah Joseph Oihoma, Clinton Health Access Initiative, Nigeria Office, Abuja, Nigeria
Jibrin Yusuf Bara, Department of Internal Medicine, Abubakar Tafawa Balewa University Teaching Hospital, Bauchi,Nigeria
Umar Hamzat Mohammed, Department of Medical Microbiology, Federal Medical Centre, Nguru, Nigeria
Gabchiya Nguru Mohammed, Department of Medical Microbiology, Federal Medical Centre, Nguru, Nigeria
Zanna Baba Ali, Department of Medical Microbiology, Federal Medical Centre, Nguru, Nigeria
Ladan Joshua, Department of Immunology and Infectious Diseases, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria
Hamidu Ibrahim, Department of Immunology and Infectious Diseases, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria
Okon Kenneth Okwong, Department of Medical Microbiology, Federal Medical Centre, Makurdi, Nigeria
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Wound infections inflict clinical and societal consequences on the patients, but its bacteriological characteristic varies with different factors. Therefore, effective treatment and management of wound infections in hospital and community setting will require detailed epidemiological knowledge of the infecting bacterial pathogens and their antibiogram peculiar to the environment. Based on this information, we examined the prevalence and antibiogram of bacterial pathogens isolated from wound infection cases seen at the hospital over the study period. A total of 392 wound swabs/ and pus of different types of wound infections from different anatomical sites and associated clinical conditions were analyzed by standard bacteriological methods. Of the 392 clinical specimens analyzed, 301(76.8%) yielded at least one bacterial pathogen, 25(6.4%) polymicrobial, no anaerobes identified and 91(23.2%) yielded no bacterial growth, gender distribution, 204(67.8%) males and 97(32.2%) females, and majority of pathogens were recovered from septic wound infections. Overall, 7 different bacterial pathogens were identified 5(71.4%) gram-negative bacteria isolates and 2(28.6%) gram-positive bacterial isolates]. Staphylococcus aureus accounted for majority of the bacterial pathogens isolated, 162(53%) followed by coliforms 62(21%) and Pseudomonas aeroginosa 57(19%). The bacterial pathogens demonstrated high resistance to ampicillin(78%), amoxicillin(66%), and cotrimoxazole(78%), in contrast to high sensitivity pattern observed with fluoroquinolones ( ofloxacin 83%,, norfloxacin 71%, ciprofloxacin 78%), erythromycin 72%, chloramphenicol 62%, gentamycin 58% and ceftazidime 60%. The relatively high number of wound infection cases seen within the study period is of public health concern, while the low number of bacterial pathogens isolated underscores the need for improvement in the laboratory diagnostic approach for effective treatment and management of wound infections.
Wound Infections, Bacterial Pathogens, Antimicrobial Susceptibility Pattern, Nguru, Nigeria
To cite this article
Bularafa Mohammed Yasidi,
Denue Ballah Akawu,
Onah Joseph Oihoma,
Jibrin Yusuf Bara,
Umar Hamzat Mohammed,
Gabchiya Nguru Mohammed,
Zanna Baba Ali,
Okon Kenneth Okwong,
Retrospective Analysis of Bacterial Pathogens Isolated from Wound Infections at a Tertiary Hospital in Nguru, Yobe State Nigeria, American Journal of Biomedical and Life Sciences.
Vol. 3, No. 1,
2015, pp. 1-6.
Kaye KS, Schmit K, Pieper C, Sloan R, Caughlan KF, Sexton DJ, Schmader KE. The effect of increasing age on the risk of surgical site infection. J Infect Dis. 2005; 191:1056-62.
Bowler PG, Duerden BI and Armstrong DG. (2001). Wound microbiology and associated approaches to wound management. Clinical Microbiology Review, 2001, 14,244-269
Shittu AO, Kolawole DO and Oyedepo EAR. A study of wound infections in two health institutions in ile-ife, Nigeria. Afr. J. Biomed. Res, 2002 .5(3): 97–102,
Akoachere Jane-Francis Tatah Kihla Palle John Ngunde Mbianda Soupsop Evelyn, Nkwelang Gerard, Roland Ndip Ndip Risk factors for wound infection in health care facilities in Buea, Cameroon: aerobic bacterial pathogens and antibiogram of isolates Pan African Medical Journal. 2014; 18:6
Kehinde A.O, Ademola S.A, Okeshola O.A,Oluwatosin O.M, Bakare R.A.Pattern of Bacterial Pathogens in Burn Wound infections in Ibadan, Nigeria. Annals of Burns and fire disasters; 2004 XVII(1)
Muluye D, Wondimeneh Y, Ferede G, Nega T, Adane K, Biadgo B, Tesfa H, Moges. Bacterial isolates and their antibiotic susceptibility patterns among patients with pus and /or wound discharge at Gondar University hospital. BMC Research Notes, 2014,7:619
Motayo BO, Akinbo JA, Ogiogwa IJ, Idowu AA, Nwanze JC, Onoh CC, Okerentugba PO, Innocent-Adiele HC and Okonko IO. Bacteria Colonization and Antibiotic Susceptibility Pattern of Wound Infections in a Hospital in Abeokuta . FS.2013, 3(1): 43-48.
Mohammedaman Mama Alemseged Abdissa and Tsegaye Sewunet.Antimicrobial susceptibility pattern of bacterial isolates from wound infection and their sensitivity to alternative topical agents at Jimma University Specialized Hospital, South-West Ethiopia. Annals of Clinical Microbiology and Antimicrobials 2014, 13:14
Okon KO, Basset P, Uba A, Lin J, Oyawoye B. Shittu A.O, Blanc.D. Co-occurrence of Predominant Panton-Valentine Leukocidin-Positive Sequence Type (ST) 152 and Multidrug-Resistant ST 241 Staphylococcus aureus clones in Nigerian Hospitals- J. Clin. Microb. 2009; 47(9);3000-3003
Ogbolu DO, Danini, Ogunledun A, Alli AO, Webber MA. High level of multidrug resistance in clinical isolates of gram negative pathogens from Nigeria.Int. J. Antimicrob. Agent. 2011;37:62-66
Cheesbrough M.(1991) Microbiology: in Medical Laboratory Manual for Tropical countries. ELBS edition.University Press, Cambridge 32;26-58.
Bauer, A.W., W.M. Kirby, J.C. Sherris and M. Turck, 1966. Antibiotic susceptibility testing by a standard single disc method. American Journal Clinical Pathology, 1966, 45:493-496.
Raminder Sandhu, Hema Prakash, RP Nagdawane, Aerobic bacterial isoltes in supprative infection and their antibiogram –a reflection of infection control.IJPBS, 4(2), 186-192.
Stephen Sixto Siguan, Bernard S. Ang, Isaac M. Pala, and Reynaldo M. Baclig, Aerobic Surgical Infection: A Surveillance on Microbiological Etiology and Antimicrobial Sensitivity Pattern of Commonly Used Antibiotics Phil J Microbiol Infect Dis 1990; 19(1):27-33
Syed Asad Ali, S. M. Tahir, Abdul Sattar Memon, Noshad A. Shaikh. Pattern of pathogens and their sensitivity isolated from superficial surgical site infections in a tertiary care hospital J Ayub Med Coll Abbottabad 2009;21(2)
Daniel SJC, Gowthani DE, Sowmiya S, (2013). Isolation and identification of bcateril pathogens from wound of diabetic patients .Int. J.Curr, Microbiol. Appl. Sci. 2(11), 72-77.
Magnet MH, Arongozeb MD, Khan GM, Ahmed Z(2013). Isolation and identification of different bacterial from different types of burns wound infection and study their antimicrobial sensitivity pattern. IJRANSS, 1(3), 123-132.
Bhat VG, Vasaikar SD Bacteriological profile and antibiogram of aerobic burn wound isolates in Mthatha, Eastern Cape, South Africa South Afr J Epidemiol Infect 2010;25(4)
Manikandan C and Amsath A Antibiotic susceptibility of bacterial strains isolated from wound infection patients in Pattukkottai, Tamilnadu, India Int.J.Curr.Microbiol.App.Sci (2013) 2(6): 195-203
Kluytman, J.A., Mouton, J.W., Ijzerman, P.F., Vanderbrouke-Grauls, C.M., Maat, A.W., Wagenvoort, J.H., and Verburgh, H.A.(1995). Nasal carriage of Staphylococcus aureus as a major risk for wound infection after cardiac surgery. Journal of Infectious Diseases,171:216-219
Shriyan A, Sheetal R, Nayak N Aerobic Micro-Organisms In Post-Operative Wound Infections And Their Antimicrobial Susceptibility Patterns Journal of Clinical and Diagnostic Research. 2010, ( 4):3392-3396