Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh

Ashfaq Imtiaz Uddin; Monira Pervin; Md. Sakil Munna; Rashed Noor

doi:doi:10.11648/j.ajbls.20140201.13

| Peer-Reviewed

Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh

Ashfaq Imtiaz Uddin, Monira Pervin, Md. Sakil Munna, Rashed Noor

Published in American Journal of Biomedical and Life Sciences (Volume 2, Issue 1)

Received: 18 January 2014 Accepted: Published: 20 February 2014

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Current investigation attempted to uncover common risk factors associated with HBsAg positivity among the suspected patients of Hepatitis B viral infection. Blood specimens were collected from patients prescribed to undergo HBsAg positivity test and tested for the detection of HBsAg through enzyme-linked immunosorbent assay (ELISA). HBsAg positivity was analyzed in relation to age, family history of HBV infection, unprotected sex, multiple sexual partners, blood transfusions, frequency of needle pricks, intravenous drug addiction, dental surgery and other surgical operations of the patients. Out of 50 patients, 23 were found to be HBsAg positive. After statistical analysis of all the factors it was deduced that patients who had unprotected sex and whose families (especially the mother of the patient) had a history of HBV infection were mostly found to be HBsAg positive. Detection of HBsAg positive cases with multiple associated risk factors revealed that the general people in Bangladesh need to be more conscious on the possible infection aware of getting infected with HBV as they are being frequently exposed subjected to the risk factors.

Published in	American Journal of Biomedical and Life Sciences (Volume 2, Issue 1)
DOI	10.11648/j.ajbls.20140201.13
Page(s)	18-21
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

HBV Infection, Prevalence; Risk Factors, HbsAg

References

[1]	F.B. Hollinger, and T.J. Liang, Hepatitis B Virus. In: Knipe DM et al. eds. Fields Virology, Philadelphia, Lippincott Williams & Wilkins, 2001.
[2]	M. Balew, F. Moges, G. Yismaw, and C. Unakal, "Assessment of hepatitis B virus and hepatitis C virus infections and associated risk factors in HIV infected patients at Debretabor hospital, South Gondar, Northwest Ethiopia," Asian Pac J Trop Dis, vol. 4(1), pp. 1-7, 2014.
[3]	A. Rahman, F. Jahan, F. Rahman, and R Noor, "Study of biochemical and immunological parameters of Hepatitis B Virus positive patients in Bangladesh," Journal of Bangladesh Academy of Sciences, vol. 37(1), pp. 51-56, 2013.
[4]	D. Lavanchy, "Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures," J Viral Hepat, vol. 11, pp. 97-107, 2004.
[5]	E.J. Aspinall, G. Hawkins, and A. Fraser, V. Hutchinson, D. Goldberg, "Hepatitis B prevention, diagnosis, treatment and care: A review," Occupational Medicine, vol. 61, pp. 531-540, 2011.
[6]	S. Bowden, Laboratory diagnosis of hepatitis B infection. In: Hepatitis B Virus, International Medical Press, London, 2002.
[7]	G. Matthews, M. Robotin, and B Positive - all you wanted to know about hepatitis B: A guide for primary care providers, Australasian Society for HIV Medicine, 2008, pp. 31-39.
[8]	F. Andre, "Hepatitis B epidemiology in Asia the Middle East and Africa," Vaccine, vol. 18, pp. 20-22, 2000.
[9]	F. Mahoney, and M. Kane, Hepatitis B Vaccines, Philadelphia: W B Saunders Company, 2004, pp. 158-182.
[10]	A. Negero, Z. Sisay, and G. Girmay-Medhin, "Prevalence of Hepatitis B surface antigen (HBsAg) among visitors of Shashemene General Hospital voluntary counseling and testing center," BMC Research Notes, vol. 4, pp. 35. 2011.
[11]	E. Sablon, and F. Shapiro, "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance," Int J Med Sci, vol. 2, pp. 8-16, 2005.
[12]	T. Shimelis, W. Torben, G. Medhin, M. Tebeje, A. Andualm, F. Demessie, and et al., "Hepatitis B virus infection among attendants of VCT and ART clinic of St Paul’s General Specialized Hospital, Addis Ababa, Ethiopia," Sex Transm Infect, vol. 84, pp. 37-41, 2007.
[13]	L.L. Lewis-Ximenez, M.R.Ó. Kycia, C.F. Ginuino, J.C. Silva1, H.G. Schatzmayr, S. Sherri-Stuver, and C.F.T. Yoshidal, "Risk factors for hepatitis B virus infection in Rio de Janeiro, Brazil," BMC Public Health, vol. 2, pp. 26. 2002.
[14]	A. Hasan, HA. Nur, R. Christian, B. Abdullah, B. Pradip, H. Lokman, A.H. Mohammed, S.H. Mohammed, B. Christoph, and G. Niklaus, "Prevalence and risk factors of hepatitis B and C virus infections in an impoverished urban community in Dhaka. Bangladesh." BMC. Infect Dis, vol. 10, pp. 208, 2010.
[15]	M. Khan, and N. Ahmad, "Seroepidemiology of HBV and HCV in Bangladesh" International Hepatology Communications, vol. 5(1) pp. 27-29. 1996.
[16]	M. Islam, K. Islam, and N. Islam, "Hepatitis-B viras infection in Dhaka, Bangladesh," J Clin Gastroenterology, vol. 38 (10), pp. 132-133, 1984.
[17]	J.G. Cappuccino, N. Sherman, Microbiology – A Laboratory Manual, California, The Benjamin/Cummings Publishing Co Inc, 1996.
[18]	M. Krajden, G. Mc-Nabb, and M. Petric, "The laboratory diagnosis of hepatitis B virus," Can J Infect Dis Med Microbial, vol. 16, pp. 65-72, 2005.
[19]	M.A. Ahmed, and M.A. Alim, "Current Challenges in Hepatitis B," TAJ, vol. 19(1), pp. 38-44, 2006.
[20]	B. Chakraborty, K. Roy, R. Noor, and M.M. Rahman, "Persistence of anti-HBs antibody and immunological memory in healthy individuals vaccinated with Hepatitis B vaccine," S J Microbiol, vol. 1(1), pp. 37-41, 2011.
[21]	D. Ganem, and R.J. Schneider, Hepadnaviridae- The Viruses and Their Replication. Philadelphia, Lippincott Williams & Wilkins, 2001.
[22]	N. Gitlin, "Hepatitis B: diagnosis, prevention, and treatment," Clinical Chemistry, vol. 43, pp. 1500- 1506, 1997.
[23]	A.S. Lok, and B.J. McMahon, "Chronic hepatitis B: Update of recommendations," Hepatology, vol. 39, pp. 857-861, 2004.
[24]	M. Khan, J.J. Dong, and S.K. Acharya, Y. Dhagwahdorj, Z. Abbas, S.M.W. Jafri, and et al., "Hepatology issues in Asia: Perspectives from regional leaders." Journal of Gastroenterology and Hepatology, vol. 19, pp. S419-S430. 2004.
[25]	M.S. Laskar, N. Harada, and F. Khan, "Prevalence of Hepatitis B Surface Antigen (HBsAg) in Viqarunnesa Noon Girl's School Children in Dhaka, Bangladesh," Cent Eur J Public Health, vol. 5, pp, 202-204, 1997.
[26]	S. Rahman, "Hepatitis B: from Blumberg to Bangladesh," Euroasian Journal of Hepato- Gastroenterology, vol. 1, pp. 42-43, 2011.
[27]	S. Rahman, M.A. Mahtab, G. Foster, M. Khan, M.F. Karim, S. Solaiman, and et al., " Epidemilogy of hepatitis B virus in Bangladeshi general population," Hepat Bil Pancreat Dis Int, vol. 7, pp. 595-600, 2008.
[28]	G. Mahmood, C.R. Debnath, and B. Biswas, "Seroprevalence of HBsAg among blood donors in Sher-E-Bangla Medical College, Barisal," Bangladesh Liver Journal, vol. 1, pp. 38-40, 2007.
[29]	R.S. Garfein, D. Vlahov, N. Galai, M.C. Doherty, and K.E. Nelson, "Viral infections in short-term injection drug users: the prevalence of the hepatitis C, hepatitis B, human immunodeficiency, and human T-lymphotropic viruses," Am J Public Health, vol. 86, pp. 655-661, 1996.
[30]	T. Shirin, T. Ahmed, A. Iqbal, M. Islam, and M.N. Islam, "Prevalence and Risk Factors of Hepatitis B Virus, Hepatitis C Virus, and Human Immunodeficiency Virus Infections among Drug Addicts in Bangladesh," J Health Popul Nutr, vol. 18, pp. 145-150. 2000.

Cite This Article

Plain Text BibTeX RIS

APA Style

Ashfaq Imtiaz Uddin, Monira Pervin, Md. Sakil Munna, Rashed Noor. (2014). Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh. American Journal of Biomedical and Life Sciences, 2(1), 18-21. https://doi.org/10.11648/j.ajbls.20140201.13

Copy | Download

ACS Style

Ashfaq Imtiaz Uddin; Monira Pervin; Md. Sakil Munna; Rashed Noor. Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh. Am. J. Biomed. Life Sci. 2014, 2(1), 18-21. doi: 10.11648/j.ajbls.20140201.13

Copy | Download

AMA Style

Ashfaq Imtiaz Uddin, Monira Pervin, Md. Sakil Munna, Rashed Noor. Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh. Am J Biomed Life Sci. 2014;2(1):18-21. doi: 10.11648/j.ajbls.20140201.13

Copy | Download

@article{10.11648/j.ajbls.20140201.13,
  author = {Ashfaq Imtiaz Uddin and Monira Pervin and Md. Sakil Munna and Rashed Noor},
  title = {Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {2},
  number = {1},
  pages = {18-21},
  doi = {10.11648/j.ajbls.20140201.13},
  url = {https://doi.org/10.11648/j.ajbls.20140201.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20140201.13},
  abstract = {Current investigation attempted to uncover common risk factors associated with HBsAg positivity among the suspected patients of Hepatitis B viral infection. Blood specimens were collected from patients prescribed to undergo HBsAg positivity test and tested for the detection of HBsAg through enzyme-linked immunosorbent assay (ELISA). HBsAg positivity was analyzed in relation to age, family history of HBV infection, unprotected sex, multiple sexual partners, blood transfusions, frequency of needle pricks, intravenous drug addiction, dental surgery and other surgical operations of the patients. Out of 50 patients, 23 were found to be HBsAg positive. After statistical analysis of all the factors it was deduced that patients who had unprotected sex and whose families (especially the mother of the patient) had a history of HBV infection were mostly found to be HBsAg positive. Detection of HBsAg positive cases with multiple associated risk factors revealed that the general people in Bangladesh need to be more conscious on the possible infection aware of getting infected with HBV as they are being frequently exposed subjected to the risk factors.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh
AU  - Ashfaq Imtiaz Uddin
AU  - Monira Pervin
AU  - Md. Sakil Munna
AU  - Rashed Noor
Y1  - 2014/02/20
PY  - 2014
N1  - https://doi.org/10.11648/j.ajbls.20140201.13
DO  - 10.11648/j.ajbls.20140201.13
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 18
EP  - 21
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20140201.13
AB  - Current investigation attempted to uncover common risk factors associated with HBsAg positivity among the suspected patients of Hepatitis B viral infection. Blood specimens were collected from patients prescribed to undergo HBsAg positivity test and tested for the detection of HBsAg through enzyme-linked immunosorbent assay (ELISA). HBsAg positivity was analyzed in relation to age, family history of HBV infection, unprotected sex, multiple sexual partners, blood transfusions, frequency of needle pricks, intravenous drug addiction, dental surgery and other surgical operations of the patients. Out of 50 patients, 23 were found to be HBsAg positive. After statistical analysis of all the factors it was deduced that patients who had unprotected sex and whose families (especially the mother of the patient) had a history of HBV infection were mostly found to be HBsAg positive. Detection of HBsAg positive cases with multiple associated risk factors revealed that the general people in Bangladesh need to be more conscious on the possible infection aware of getting infected with HBV as they are being frequently exposed subjected to the risk factors.
VL  - 2
IS  - 1
ER  -

Copy | Download

Author Information

Ashfaq Imtiaz Uddin

Department of Microbiology, Stamford University Bangladesh, Dhaka, Bangladesh
Monira Pervin

Department of Virology, Dhaka Medical College and Hospital (DMCH), Dhaka, Bangladesh
Md. Sakil Munna

Department of Microbiology, Stamford University Bangladesh, Dhaka, Bangladesh
Rashed Noor

Department of Microbiology, Stamford University Bangladesh, Dhaka, Bangladesh

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Ashfaq Imtiaz Uddin, Monira Pervin, Md. Sakil Munna, Rashed Noor. (2014). Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh. American Journal of Biomedical and Life Sciences, 2(1), 18-21. https://doi.org/10.11648/j.ajbls.20140201.13

Copy | Download

ACS Style

Ashfaq Imtiaz Uddin; Monira Pervin; Md. Sakil Munna; Rashed Noor. Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh. Am. J. Biomed. Life Sci. 2014, 2(1), 18-21. doi: 10.11648/j.ajbls.20140201.13

Copy | Download

AMA Style

Ashfaq Imtiaz Uddin, Monira Pervin, Md. Sakil Munna, Rashed Noor. Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh. Am J Biomed Life Sci. 2014;2(1):18-21. doi: 10.11648/j.ajbls.20140201.13

Copy | Download

@article{10.11648/j.ajbls.20140201.13,
  author = {Ashfaq Imtiaz Uddin and Monira Pervin and Md. Sakil Munna and Rashed Noor},
  title = {Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {2},
  number = {1},
  pages = {18-21},
  doi = {10.11648/j.ajbls.20140201.13},
  url = {https://doi.org/10.11648/j.ajbls.20140201.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20140201.13},
  abstract = {Current investigation attempted to uncover common risk factors associated with HBsAg positivity among the suspected patients of Hepatitis B viral infection. Blood specimens were collected from patients prescribed to undergo HBsAg positivity test and tested for the detection of HBsAg through enzyme-linked immunosorbent assay (ELISA). HBsAg positivity was analyzed in relation to age, family history of HBV infection, unprotected sex, multiple sexual partners, blood transfusions, frequency of needle pricks, intravenous drug addiction, dental surgery and other surgical operations of the patients. Out of 50 patients, 23 were found to be HBsAg positive. After statistical analysis of all the factors it was deduced that patients who had unprotected sex and whose families (especially the mother of the patient) had a history of HBV infection were mostly found to be HBsAg positive. Detection of HBsAg positive cases with multiple associated risk factors revealed that the general people in Bangladesh need to be more conscious on the possible infection aware of getting infected with HBV as they are being frequently exposed subjected to the risk factors.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - Study of Risk Factors Related to HBsAg Reactivity among Outdoor Patients in Dhaka Medical College and Hospital, Bangladesh
AU  - Ashfaq Imtiaz Uddin
AU  - Monira Pervin
AU  - Md. Sakil Munna
AU  - Rashed Noor
Y1  - 2014/02/20
PY  - 2014
N1  - https://doi.org/10.11648/j.ajbls.20140201.13
DO  - 10.11648/j.ajbls.20140201.13
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 18
EP  - 21
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20140201.13
AB  - Current investigation attempted to uncover common risk factors associated with HBsAg positivity among the suspected patients of Hepatitis B viral infection. Blood specimens were collected from patients prescribed to undergo HBsAg positivity test and tested for the detection of HBsAg through enzyme-linked immunosorbent assay (ELISA). HBsAg positivity was analyzed in relation to age, family history of HBV infection, unprotected sex, multiple sexual partners, blood transfusions, frequency of needle pricks, intravenous drug addiction, dental surgery and other surgical operations of the patients. Out of 50 patients, 23 were found to be HBsAg positive. After statistical analysis of all the factors it was deduced that patients who had unprotected sex and whose families (especially the mother of the patient) had a history of HBV infection were mostly found to be HBsAg positive. Detection of HBsAg positive cases with multiple associated risk factors revealed that the general people in Bangladesh need to be more conscious on the possible infection aware of getting infected with HBV as they are being frequently exposed subjected to the risk factors.
VL  - 2
IS  - 1
ER  -

Copy | Download