Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases

Garango Allaye; Bougar Faissal; Hattab Mohammed Koussay; Kebbaj Houda; Fawzi Saad; Mansouri Nadia Hattab

doi:doi:10.11648/j.ijcoms.20190502.13

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Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases

Garango Allaye, Bougar Faissal, Hattab Mohammed Koussay, Kebbaj Houda, Fawzi Saad, Mansouri Nadia Hattab

Published in International Journal of Clinical Oral and Maxillofacial Surgery (Volume 5, Issue 2)

Received: 10 September 2019 Accepted: 5 October 2019 Published: 26 October 2019

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Abstract

Our retrospective study is about 70 cases of cancers of the Oral cavity, collected at the department of maxillo-facial surgery in Mohamed VI hospital university of Marrakech, during 9 years (January 2007-January2016). The mean age has been 60 years (20-94 years old). The women predominate with a ratio, which equal 0.94. Among the etiologic factors, tobacco is 31% of our cases and alcohol 6% of our case _Clinically, the mean delay of consultation has been 8 months_the clinical symptomatology has often consisted in the oral cavity lesions (80%), pain has been the second symptom (33%), the difficulty in swallowing and the difficulty in chewing (18%) and clinical examination showed a ulcero budding tumor in 38% of the cases, the cervical adenopathies have been noticed in 47% of the cases. The definitive diagnosis has been based on the histologic analysis that showed an epidermoid carcinoma in 87% of the cases. According to the TNM classification, the T3 are noticed in 46% and the No is found in 54%. The therapeutic strategy consisted in the surgery alone (58%), the surgery with radiotherapy (33%), the radiotherapy just (9%). Among our patients, we noticed a local recidivism in 3 cases, and we noticedtwo cases of metastasis, 35 patients (50%) are still a live with good carcinologic and functional result, 10 patients died; the other patients have been lost to follow-up.

Published in	International Journal of Clinical Oral and Maxillofacial Surgery (Volume 5, Issue 2)
DOI	10.11648/j.ijcoms.20190502.13
Page(s)	47-55
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Oral Cavite, Cancer, Epidemiology, Surgery, Radiotherapy, Chemotherapy

References

[1]	Augustint., Mathiew M., Tarcissus K., Hierrhum Aboubacar b., Dieudonne O, Simon T: Les cancers de la cavité buccale: affection à prédominance féminine à Ouagadougou Med Buccale Chir Buccale 2015; 21: 61-66.
[2]	Aka Gblanh K. F. P: Les tumeurs malignes bucco-maxillo-faciales: étude statistique thérapeutique: à propos de 119 cas: Thèse de médecine 1163 N° 91/Abidjan.
[3]	Magne Tamga Denise Diane: Etude épidémiologique et histopathologieque des cancers stomatologique et maxillo-faciaux: à propos de 70 cas: Thèse en médecine dentaire 2007/Mali.
[4]	Barthelemy, Sannajust J., P., Mondie J. M: Cancers de la cavité buccale: Préambule, épidémiologie, etude clinique EMC-Stomatologie 1 (2005) 277-294.
[5]	M. M. Dieng, A. Dem, P. M Gaye, D. Diouf, S. Toure, R. Diop, M. Ndiaye, B. Loum: Cancers de la cavité buccale: à propos de 145 cas à l’institut joliot-curie de Dakar Posters/ Cancer/Radiothérapie 16 (2012) 524-581.
[6]	Thariat J: Évolution des concepts dans les cancers des voies aérodigestives supérieures. Bull Cancer 2013; 100: 983-97.
[7]	Prades J. M., Shmitt T., Timoshenko A: Cancers de la langue. EMC, ORL 1, 2004. P. 35-55.
[8]	Crissman JD, Sakrwa: Squamous neoplasia of the upper aerodigestive tract. Intraepithelial and invasive squamous cell carcinoma. In: Head and neck Surgical pathology, Pilch BZ. Philadelphia, Lippincott Williamn & Wilkins 2001: p 34-52.
[9]	Szpirglas H., Guilbert F: Cancers de la cavité buccale. Préambule. Encycl Méd Chir (Elsevier SAS, Paris), (stomatologie, 22-063-A-05), 1996.
[10]	Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, et AL: Cancer incidence and mortality patterns in Europe: Estimates for countries in 2012. European Journal of Cancer (2013) 49, 1374-1403.
[11]	Centre International de Recherche sur le Cancer: Communiqué de presse N° 164: OMS 3 Juin 2005.
[12]	Brugere J: Les cancers des VADS la ligue nationale contre le cancer. Bulletin Novembre 2002 15 p.
[13]	Gnepp DR. Diagnostic Surgical Pathology of the head and neck: Philadelphia, Sanders ed, 2000, 888 pages.
[14]	Rodrigues P. C, Miguel M. C. C, Bagordakis E. and al: Clinicopathological prognostic factors of oral tongue squamous cell carcinoma: a retrospective study of 202 cases. Int. J. Oral maxillofac. Surg. 2014; 43: 795-801.
[15]	A. Auperin, C. Hill: Epidémiologie des carcinomes des voies aérodigestives supérieures Cancer/Radiothérapie 9 (2005) 1-7.
[16]	Remonter L., Buemi A, Velten M., Jougla E., Esteve J: Evolution de l’incidence et de la hortalité par cancer en France de 1978 à2000. Saint-Maurice: Instiut de veille sanitaire; 2003.
[17]	Hill C: Epidemiology of cancer of upper aerodigestive trac. Bull cancer 2000; 5 (suppl): 5-8.
[18]	Rothman K., Keller A: The effect of joint exposure to alcohol and tabacco on risk of the month and the pharynx. J Chronic Dis 1972; 25: 711-6.
[19]	Laurent B: Cancer de la langue mobile: facteurs pronostiques des carcinomes epidermoides T1-T2 de la lange mobile. Thèse médicale Nantes, 2006.
[20]	Bouyakhlef M: Cancers de la langue mobile. Thèse de médecine N° 214, 2002, Casablanca.
[21]	Eisenberg E: Oral lichen planus: A benign lesion. J Oral Maxillofac surg 2000; 58: 1278-1285.
[22]	Buisset E, Leferbe JL, et al: Les cancers linguaux et pelvi-lingaux: valeur pronostique de l’envahissement anglionnaire. A propos de 744 cas. Ann Oto-laryngol Chir Cervicofac 1989; 106, 8: 551-555.
[23]	Manual, Cancer Staging Handbook from the AJCC Cancer Staging: New York: Springer-Verlag: 2002.
[24]	Barnes L, Eveson JW, Reichart P, Sidransky D: World Health Organization international classification. Pathology and genetics of Head and Neck tumors. Lyon, IARC Press, 2005, 430 pages.
[25]	Piette R: Traité de pathologie buccale et maxilla-faciale. Université de bruxelles 1991, P 502-511.
[26]	Pinsolle J., Demeaux H., Coustal B., Siberchicot f, Caudry M., Maitre J. P., Michelet f. X: Results of surgical treatement of T3 and T4 tumors of the oral cavity and oropharynx. Am. J. Surg. 1992, 164: 587-91.
[27]	Menegoz F., Lesch JM., Rame JP., Reyt e. Bauvin E., Areveux P, et al: Les cancers d la lèvre, de la cavité buccale et du pharynx en France: incidence, mortalité et tendance (période 1975-1995). Bull Cancer 2002; 89: 419-429.
[28]	Lebeau J: Cancer du plancher buccal, des joues, des lèvres, de la voute palatine et des gencives. Rev du praticien 40-33. Paris 1990.
[29]	Toure S., Sonko L., Diallo B. K., Diop A: Profil épidémiologique des cancers de la cavité buccale au sénegal. Revue de stomatologie et de chirurgie maxillo-faciale Vol 106- N° SUP 4- Septembre 2005, P 68, Masson, Paris, 2005.
[30]	Gehanno P, Baillet F, Brujer J, et al: Cancers de la langue. Encycl Méd Chir Oto-Rhino-Laryngologie 1995; 20-627-A-10: 12 p.
[31]	Pinsolle J, Mauruc B: Cancer de la langue: étiologie, diagnostic, évolution et pronostic, principes du traitement Rev Prat 1990; 40, 19: 1811-1814.
[32]	Aksu G. et al: Treatement results and prognostic factors in oral tongue cancer: analysis of 80 Patients. Int. J. Oral maxillofac. Surg. 2006; 35: 506-513.
[33]	Azerad J: La physiologie de la manducation. Paris: Masson 1992-175 p.
[34]	Younes Y: Les cancers de la cavité buccale: à propos de 256 cas. Thèse Med.: Dakar 1996, N° 33.
[35]	Robbins KT, Clayman G, Levine PA, Medina J, Sessions R, Shaha A, et al: Neck dissection classification update: revisions proposed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery. Arch Otolaryngol Head 2002, 128: 751–8.
[36]	Pevel D, Marc R: Précis d’audiophonologie et de déglutition. Tome II. Les voies aéro digéstives supérieurs. Marseille; 2009; p. 54.
[37]	Perrinaud A: Carcinomes épidermoïdes. Presse Med. 2008; 37: 1485–9.
[38]	Mazeron JJ. Et al: Cancer de la langue mobile. Le concours médical 1988; 110, 44: 4051.

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APA Style

Garango Allaye, Bougar Faissal, Hattab Mohammed Koussay, Kebbaj Houda, Fawzi Saad, et al. (2019). Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases. International Journal of Clinical Oral and Maxillofacial Surgery, 5(2), 47-55. https://doi.org/10.11648/j.ijcoms.20190502.13

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ACS Style

Garango Allaye; Bougar Faissal; Hattab Mohammed Koussay; Kebbaj Houda; Fawzi Saad, et al. Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases. Int. J. Clin. Oral Maxillofac. Surg. 2019, 5(2), 47-55. doi: 10.11648/j.ijcoms.20190502.13

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AMA Style

Garango Allaye, Bougar Faissal, Hattab Mohammed Koussay, Kebbaj Houda, Fawzi Saad, et al. Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases. Int J Clin Oral Maxillofac Surg. 2019;5(2):47-55. doi: 10.11648/j.ijcoms.20190502.13

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@article{10.11648/j.ijcoms.20190502.13,
  author = {Garango Allaye and Bougar Faissal and Hattab Mohammed Koussay and Kebbaj Houda and Fawzi Saad and Mansouri Nadia Hattab},
  title = {Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {5},
  number = {2},
  pages = {47-55},
  doi = {10.11648/j.ijcoms.20190502.13},
  url = {https://doi.org/10.11648/j.ijcoms.20190502.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20190502.13},
  abstract = {Our retrospective study is about 70 cases of cancers of the Oral cavity, collected at the department of maxillo-facial surgery in Mohamed VI hospital university of Marrakech, during 9 years (January 2007-January2016). The mean age has been 60 years (20-94 years old). The women predominate with a ratio, which equal 0.94. Among the etiologic factors, tobacco is 31% of our cases and alcohol 6% of our case _Clinically, the mean delay of consultation has been 8 months_the clinical symptomatology has often consisted in the oral cavity lesions (80%), pain has been the second symptom (33%), the difficulty in swallowing and the difficulty in chewing (18%) and clinical examination showed a ulcero budding tumor in 38% of the cases, the cervical adenopathies have been noticed in 47% of the cases. The definitive diagnosis has been based on the histologic analysis that showed an epidermoid carcinoma in 87% of the cases. According to the TNM classification, the T3 are noticed in 46% and the No is found in 54%. The therapeutic strategy consisted in the surgery alone (58%), the surgery with radiotherapy (33%), the radiotherapy just (9%). Among our patients, we noticed a local recidivism in 3 cases, and we noticedtwo cases of metastasis, 35 patients (50%) are still a live with good carcinologic and functional result, 10 patients died; the other patients have been lost to follow-up.},
 year = {2019}
}

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TY  - JOUR
T1  - Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases
AU  - Garango Allaye
AU  - Bougar Faissal
AU  - Hattab Mohammed Koussay
AU  - Kebbaj Houda
AU  - Fawzi Saad
AU  - Mansouri Nadia Hattab
Y1  - 2019/10/26
PY  - 2019
N1  - https://doi.org/10.11648/j.ijcoms.20190502.13
DO  - 10.11648/j.ijcoms.20190502.13
T2  - International Journal of Clinical Oral and Maxillofacial Surgery
JF  - International Journal of Clinical Oral and Maxillofacial Surgery
JO  - International Journal of Clinical Oral and Maxillofacial Surgery
SP  - 47
EP  - 55
PB  - Science Publishing Group
SN  - 2472-1344
UR  - https://doi.org/10.11648/j.ijcoms.20190502.13
AB  - Our retrospective study is about 70 cases of cancers of the Oral cavity, collected at the department of maxillo-facial surgery in Mohamed VI hospital university of Marrakech, during 9 years (January 2007-January2016). The mean age has been 60 years (20-94 years old). The women predominate with a ratio, which equal 0.94. Among the etiologic factors, tobacco is 31% of our cases and alcohol 6% of our case _Clinically, the mean delay of consultation has been 8 months_the clinical symptomatology has often consisted in the oral cavity lesions (80%), pain has been the second symptom (33%), the difficulty in swallowing and the difficulty in chewing (18%) and clinical examination showed a ulcero budding tumor in 38% of the cases, the cervical adenopathies have been noticed in 47% of the cases. The definitive diagnosis has been based on the histologic analysis that showed an epidermoid carcinoma in 87% of the cases. According to the TNM classification, the T3 are noticed in 46% and the No is found in 54%. The therapeutic strategy consisted in the surgery alone (58%), the surgery with radiotherapy (33%), the radiotherapy just (9%). Among our patients, we noticed a local recidivism in 3 cases, and we noticedtwo cases of metastasis, 35 patients (50%) are still a live with good carcinologic and functional result, 10 patients died; the other patients have been lost to follow-up.
VL  - 5
IS  - 2
ER  -

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Author Information

Garango Allaye

Department of Oral and Maxillo-facial Surgery, Cadi Ayyad University, Marrakech, Morocco
Bougar Faissal

Department of Oral and Maxillo-facial Surgery, Cadi Ayyad University, Marrakech, Morocco
Hattab Mohammed Koussay

Department of Oral and Maxillo-facial Surgery, Cadi Ayyad University, Marrakech, Morocco
Kebbaj Houda

Department of Oral and Maxillo-facial Surgery, Cadi Ayyad University, Marrakech, Morocco
Fawzi Saad

Department of Oral and Maxillo-facial Surgery, Cadi Ayyad University, Marrakech, Morocco
Mansouri Nadia Hattab

Department of Oral and Maxillo-facial Surgery, Cadi Ayyad University, Marrakech, Morocco

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APA Style

Garango Allaye, Bougar Faissal, Hattab Mohammed Koussay, Kebbaj Houda, Fawzi Saad, et al. (2019). Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases. International Journal of Clinical Oral and Maxillofacial Surgery, 5(2), 47-55. https://doi.org/10.11648/j.ijcoms.20190502.13

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ACS Style

Garango Allaye; Bougar Faissal; Hattab Mohammed Koussay; Kebbaj Houda; Fawzi Saad, et al. Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases. Int. J. Clin. Oral Maxillofac. Surg. 2019, 5(2), 47-55. doi: 10.11648/j.ijcoms.20190502.13

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AMA Style

Garango Allaye, Bougar Faissal, Hattab Mohammed Koussay, Kebbaj Houda, Fawzi Saad, et al. Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases. Int J Clin Oral Maxillofac Surg. 2019;5(2):47-55. doi: 10.11648/j.ijcoms.20190502.13

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@article{10.11648/j.ijcoms.20190502.13,
  author = {Garango Allaye and Bougar Faissal and Hattab Mohammed Koussay and Kebbaj Houda and Fawzi Saad and Mansouri Nadia Hattab},
  title = {Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {5},
  number = {2},
  pages = {47-55},
  doi = {10.11648/j.ijcoms.20190502.13},
  url = {https://doi.org/10.11648/j.ijcoms.20190502.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20190502.13},
  abstract = {Our retrospective study is about 70 cases of cancers of the Oral cavity, collected at the department of maxillo-facial surgery in Mohamed VI hospital university of Marrakech, during 9 years (January 2007-January2016). The mean age has been 60 years (20-94 years old). The women predominate with a ratio, which equal 0.94. Among the etiologic factors, tobacco is 31% of our cases and alcohol 6% of our case _Clinically, the mean delay of consultation has been 8 months_the clinical symptomatology has often consisted in the oral cavity lesions (80%), pain has been the second symptom (33%), the difficulty in swallowing and the difficulty in chewing (18%) and clinical examination showed a ulcero budding tumor in 38% of the cases, the cervical adenopathies have been noticed in 47% of the cases. The definitive diagnosis has been based on the histologic analysis that showed an epidermoid carcinoma in 87% of the cases. According to the TNM classification, the T3 are noticed in 46% and the No is found in 54%. The therapeutic strategy consisted in the surgery alone (58%), the surgery with radiotherapy (33%), the radiotherapy just (9%). Among our patients, we noticed a local recidivism in 3 cases, and we noticedtwo cases of metastasis, 35 patients (50%) are still a live with good carcinologic and functional result, 10 patients died; the other patients have been lost to follow-up.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Cancers of Oral Cavity Epidemiological and Clinical Study About 70 Cases
AU  - Garango Allaye
AU  - Bougar Faissal
AU  - Hattab Mohammed Koussay
AU  - Kebbaj Houda
AU  - Fawzi Saad
AU  - Mansouri Nadia Hattab
Y1  - 2019/10/26
PY  - 2019
N1  - https://doi.org/10.11648/j.ijcoms.20190502.13
DO  - 10.11648/j.ijcoms.20190502.13
T2  - International Journal of Clinical Oral and Maxillofacial Surgery
JF  - International Journal of Clinical Oral and Maxillofacial Surgery
JO  - International Journal of Clinical Oral and Maxillofacial Surgery
SP  - 47
EP  - 55
PB  - Science Publishing Group
SN  - 2472-1344
UR  - https://doi.org/10.11648/j.ijcoms.20190502.13
AB  - Our retrospective study is about 70 cases of cancers of the Oral cavity, collected at the department of maxillo-facial surgery in Mohamed VI hospital university of Marrakech, during 9 years (January 2007-January2016). The mean age has been 60 years (20-94 years old). The women predominate with a ratio, which equal 0.94. Among the etiologic factors, tobacco is 31% of our cases and alcohol 6% of our case _Clinically, the mean delay of consultation has been 8 months_the clinical symptomatology has often consisted in the oral cavity lesions (80%), pain has been the second symptom (33%), the difficulty in swallowing and the difficulty in chewing (18%) and clinical examination showed a ulcero budding tumor in 38% of the cases, the cervical adenopathies have been noticed in 47% of the cases. The definitive diagnosis has been based on the histologic analysis that showed an epidermoid carcinoma in 87% of the cases. According to the TNM classification, the T3 are noticed in 46% and the No is found in 54%. The therapeutic strategy consisted in the surgery alone (58%), the surgery with radiotherapy (33%), the radiotherapy just (9%). Among our patients, we noticed a local recidivism in 3 cases, and we noticedtwo cases of metastasis, 35 patients (50%) are still a live with good carcinologic and functional result, 10 patients died; the other patients have been lost to follow-up.
VL  - 5
IS  - 2
ER  -

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