Archive
2019, Volume 5
2018, Volume 4
2017, Volume 3
2016, Volume 2
2015, Volume 1
Special Issues
Home / Journals / Medicine, Health & Food / International Journal of Clinical Oral and Maxillofacial Surgery / Article
Efficacy of Alendronic Acid/Colcalciferol Plus Calcium in the Treatment of Massive Osteolysis of Mandible
International Journal of Clinical Oral and Maxillofacial Surgery
Volume 1, Issue 1, June 2015, Pages: 1-3
Received: Jun. 3, 2015; Accepted: Jun. 16, 2015; Published: Jun. 17, 2015
Volume 1, Issue 1, June 2015, Pages: 1-3
Received: Jun. 3, 2015; Accepted: Jun. 16, 2015; Published: Jun. 17, 2015
Views 3315 Downloads 59
Author
Emad T. Daif, Oral & Maxillofacial Surgery Department, Faculty of Oral & Dental Medicine, Cairo University, Maadi, Cairo, Egypt
Abstract
Objectives: This study was carried out to evaluate the efficacy of alendronic acid / colcalciferol plus Calcium in management of edentulous patients with a severe bilateral resorption of the mandible. Materials and methods: Twenty edentulous patients with severely resorbed mandibles have been managed by alendronic acid / colcalciferol plus Calcium tablets. They were followed-up clinically and radiologically for one year. Results: The results were promising for nineteen patients (95%) where the radiographic density and height of the bone have been improved. However, the treatment was unsuccessful for one patient who was elder, 89 years old, than the others. Conclusions: On the basis of our findings, we encourage the use of alendronic acid / colcalciferol plus calcium in management of mandibular osteolysis particularly in young age.
Keywords
Osteolysis of Mandible, Vanishing Mandible, Gorham’s Disease
To cite this article
Emad T. Daif,
Efficacy of Alendronic Acid/Colcalciferol Plus Calcium in the Treatment of Massive Osteolysis of Mandible, International Journal of Clinical Oral and Maxillofacial Surgery.
Vol. 1, No. 1,
2015, pp. 1-3.
doi: 10.11648/j.ijcoms.20150101.11
References
[1]
Sharma A, Iyer N, Mittal A, Das D, Sharma S. Vanishing mandible. J Oral Sci 2010; 52:513-6.
[2]
Reddy S, Jatti D. Gorham's disease: a report of a case with mandibular involvement in a 10-year follow-up study. Dentomaxillofac Radiol 2012 ; 41:520-4.
[3]
Raghuveer HP, Jayalekshmy R. Gorham's massive osteolysis of the mandible – a progressive radiographic presentation. Dentomaxillofac Radiol 2009; 38:292-5.
[4]
Mignogna MD, Fedele S, Lo Russo L, Lanza A, Marenzi G, Sammartino G. Gorham's disease of the mandible mimicking periodontal disease on radiograph. J Clin Periodontol 2005; 32:1022-6.
[5]
Escande C, Schouman T, Françoise G, Haroche J, Ménard P, Piette JC, Bertrand JC, Ruhin-Poncet B. Histological features and management of a mandibular Gorham disease: a case report and review of maxillofacial cases in the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 106:e30-7.
[6]
Bouloux GF, Walker DM, McKellar G. Massive osteolysis of the mandible: report of a case with multifocal bone loss. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 87:357-61.
[7]
He J, He Y, Qiu W, Zhu H. Gorham disease in the maxilla. J Craniofac Surg 2012; 23:e293-5.
[8]
Kale MV, Gadre KS, Kulkarni AU. Progressive, massive osteolysis of mandible (Gorham's disease): report of a case. BMJ Case Rep 2012 8; 2012.
[9]
Möller G, Priemel M, Amling M, Werner M, Kuhlmey AS, Delling G. The Gorham-Stout syndrome (Gorham's massive osteolysis). A report of six cases with histopathological findings. J Bone Joint Surg Br 1999; 81:501-6.
[10]
Heffez L, Doku HC, Carter BL, Feeney JE. Perspectives on massive osteolysis. Report of a case and review of the literature. Oral Surg Oral Med Oral Pathol 1983; 55:331-43.
[11]
Devlin RD, Bone HG 3rd, Roodman GD. Interleukin-6: a potential mediator of the massive osteolysis in patients with Gorham-Stout disease. J Clin Endocrinol Metab 1996; 81:1893-7.
[12]
Takeda Y, Kuroda M, Suzuki A, Fujioka Y, Takayama K. Massive osteolysis of the mandible. Acta Pathol Jpn 1987; 37:677-84.
[13]
Mathias K, Hoffmann J, Martin K. [Gorham-Stout syndrome of the mandible]. Radiologe 1986; 26:439-41.
[14]
Deng R, Tang E, Lu M. Massive osteolysis of the mandible. J Craniofac Surg 2011; 22:2386-8.
[15]
Skidmore TB, Lee CM, Abbott TM, Wiggins RH 3rd, Anderson GE, Tward JD, Hitchcock Y. Gorham disease of the mandible: radiographic findings and radiotherapy response. Ear Nose Throat J 2008; 87:E4-7.
[16]
Paley MD, Lloyd CJ, Penfold CN. Total mandibular reconstruction for massive osteolysis of the mandible (Gorham-Stout syndrome). Br J Oral Maxillofac Surg 2005; 43:166-8.
[17]
Lopes N, Oliveira DM, Vajgel A, Pita I, Bezerra T, Vasconcellos RJ. A new approach for reconstruction of a severely atrophic mandible. J Oral maxillofac Surg 2009; 67:2455-9.
[18]
Melo LG, Almeida AL, Lopes JF, Rezende ML, Neto JS, Ciporkin F, Nagata MJ. A modified approach for vestibuloplasty in severely resorbed mandible using an implant-retained postoperative stent: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 106:e7-14.
[19]
Huang Y, Wang L, Wen Y, Zhang Q, Li L. Progressively bilateral resorption of the mandible. J Craniomaxillofac Surg 2012; 40:e174-7.
[20]
Gondivkar SM, Gadbail AR. Gorham-Stout syndrome: a rare clinical entity and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109:e41-8.
[21]
Avelar RL, Martins VB, Antunes AA, de Oliveira Neto PJ, Andrade ES. Use of zoledronic acid in the treatment of Gorham's disease. Int J Pediatr Otorhinolaryngol 2010; 74:319-22.
[22]
Mignogna MD, Fedele S, Lo Russo L, Ciccarelli R. Treatment of Gorham's disease with zoledronic acid. Oral Oncol 2005; 41:747-50.
PUBLICATION SERVICES
JOIN US
SPECIAL SERVICES
ADDRESS
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
U.S.A.
Tel: (001)347-983-5186
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
U.S.A.
Tel: (001)347-983-5186
FOLLOW SciencePG
