Biomedical Sciences

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Phytochemical Screening and in Vitro Antimicrobial Activity of Waltheria Indica Linn Leaf Extracts

Received: 20 August 2017    Accepted: 31 August 2017    Published: 06 October 2017
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Abstract

The plant, Waltherica indica Linn is known to possess medicinal properties according to African folklore. Scientific verification of its bioactive constituents backing its use for the treatment of upper respiratory tract infections is limited. This study aimed at evaluating the phytochemical compounds present in the crude leaf extracts as well as identify their pathogen-specific antagonistic activities. The results obtained revealed that alkaloids, cardiac glycosides, phenolic acids, saponins, steroids, tannins and terpenoids were present in the extracts. The results also revealed that the zones of inhibition from the acidic, basic, neutral polar and non-polar fractions ranged between 24-28mm against the organisms (Staphylococcus aureus, Streptococcus pneumonia, Streptococcus pyrogens, Klebsciella pneumonia, and Candida krusei). The Minimal Inhibitory Concentration (MICs) of the crude, acidic, basic, neutral polar and non-polar fractions of the leaf was recorded at 2.5mg/ml and 0.5mg/ml respectively. The results obtained suggested that the leaf of the studied plant possess strong antimicrobial activities against selected bacterial and fungal species with direct correlation to the actions of their phyto-constituents.

DOI 10.11648/j.bs.20170305.11
Published in Biomedical Sciences (Volume 3, Issue 5, September 2017)
Page(s) 86-93
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Waltherica Indica Linn Leaf, Phytochemicals, Anti-microbial Activity

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Author Information
  • Department of Chemistry, University of Abuja, Abuja, Nigeria

  • Department of Chemistry, University of Abuja, Abuja, Nigeria; Chemistry Advanced Research Centre, Sheda Science and Technology Complex (SHESTCO), Abuja, Nigeria

  • Chemistry Advanced Research Centre, Sheda Science and Technology Complex (SHESTCO), Abuja, Nigeria

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    Okwute Simon Koma, Olakunle Ayodeji Fatokun, Orishadipe Abayomi Theophilus. (2017). Phytochemical Screening and in Vitro Antimicrobial Activity of Waltheria Indica Linn Leaf Extracts. Biomedical Sciences, 3(5), 86-93. https://doi.org/10.11648/j.bs.20170305.11

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    ACS Style

    Okwute Simon Koma; Olakunle Ayodeji Fatokun; Orishadipe Abayomi Theophilus. Phytochemical Screening and in Vitro Antimicrobial Activity of Waltheria Indica Linn Leaf Extracts. Biomed. Sci. 2017, 3(5), 86-93. doi: 10.11648/j.bs.20170305.11

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    AMA Style

    Okwute Simon Koma, Olakunle Ayodeji Fatokun, Orishadipe Abayomi Theophilus. Phytochemical Screening and in Vitro Antimicrobial Activity of Waltheria Indica Linn Leaf Extracts. Biomed Sci. 2017;3(5):86-93. doi: 10.11648/j.bs.20170305.11

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  • @article{10.11648/j.bs.20170305.11,
      author = {Okwute Simon Koma and Olakunle Ayodeji Fatokun and Orishadipe Abayomi Theophilus},
      title = {Phytochemical Screening and in Vitro Antimicrobial Activity of Waltheria Indica Linn Leaf Extracts},
      journal = {Biomedical Sciences},
      volume = {3},
      number = {5},
      pages = {86-93},
      doi = {10.11648/j.bs.20170305.11},
      url = {https://doi.org/10.11648/j.bs.20170305.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.bs.20170305.11},
      abstract = {The plant, Waltherica indica Linn is known to possess medicinal properties according to African folklore. Scientific verification of its bioactive constituents backing its use for the treatment of upper respiratory tract infections is limited. This study aimed at evaluating the phytochemical compounds present in the crude leaf extracts as well as identify their pathogen-specific antagonistic activities. The results obtained revealed that alkaloids, cardiac glycosides, phenolic acids, saponins, steroids, tannins and terpenoids were present in the extracts. The results also revealed that the zones of inhibition from the acidic, basic, neutral polar and non-polar fractions ranged between 24-28mm against the organisms  (Staphylococcus aureus, Streptococcus pneumonia, Streptococcus pyrogens, Klebsciella pneumonia, and Candida krusei). The Minimal Inhibitory Concentration (MICs) of the crude, acidic, basic, neutral polar and non-polar fractions of the leaf was recorded at 2.5mg/ml and 0.5mg/ml respectively. The results obtained suggested that the leaf of the studied plant possess strong antimicrobial activities against selected bacterial and fungal species with direct correlation to the actions of their phyto-constituents.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Phytochemical Screening and in Vitro Antimicrobial Activity of Waltheria Indica Linn Leaf Extracts
    AU  - Okwute Simon Koma
    AU  - Olakunle Ayodeji Fatokun
    AU  - Orishadipe Abayomi Theophilus
    Y1  - 2017/10/06
    PY  - 2017
    N1  - https://doi.org/10.11648/j.bs.20170305.11
    DO  - 10.11648/j.bs.20170305.11
    T2  - Biomedical Sciences
    JF  - Biomedical Sciences
    JO  - Biomedical Sciences
    SP  - 86
    EP  - 93
    PB  - Science Publishing Group
    SN  - 2575-3932
    UR  - https://doi.org/10.11648/j.bs.20170305.11
    AB  - The plant, Waltherica indica Linn is known to possess medicinal properties according to African folklore. Scientific verification of its bioactive constituents backing its use for the treatment of upper respiratory tract infections is limited. This study aimed at evaluating the phytochemical compounds present in the crude leaf extracts as well as identify their pathogen-specific antagonistic activities. The results obtained revealed that alkaloids, cardiac glycosides, phenolic acids, saponins, steroids, tannins and terpenoids were present in the extracts. The results also revealed that the zones of inhibition from the acidic, basic, neutral polar and non-polar fractions ranged between 24-28mm against the organisms  (Staphylococcus aureus, Streptococcus pneumonia, Streptococcus pyrogens, Klebsciella pneumonia, and Candida krusei). The Minimal Inhibitory Concentration (MICs) of the crude, acidic, basic, neutral polar and non-polar fractions of the leaf was recorded at 2.5mg/ml and 0.5mg/ml respectively. The results obtained suggested that the leaf of the studied plant possess strong antimicrobial activities against selected bacterial and fungal species with direct correlation to the actions of their phyto-constituents.
    VL  - 3
    IS  - 5
    ER  - 

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