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A Review on Erectile Dysfunction Among Hypertensive Patients on Pharmacotherapy

Received: 12 November 2017    Accepted: 27 November 2017    Published: 21 December 2017
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Abstract

Hypertension and its related disorders have a high mortality as well as morbidity and require strict adherence to medications in order to mitigate these consequences. Sexual dysfunction is prevalent among patients with hypertension and can either be attributed to the disease progression or as a result of antihypertensive medications. Most patients report the symptoms after initiation therapy and sometimes leads to a spurious association with antihypertensive drugs. However, most drugs in the antihypertensive classes have been associated with sexual dysfunction in both men and women. The most implicated drugs are diuretics, beta-blockers, and centrally acting agents while angiotensin modulating drugs have proved to improve upon erectile dysfunction. The older generation of antihypertensive medications tends to have a negative impact on sexual performance. Females experience sexual dysfunction associated with hypertension and its treatment, but this is grossly under-reported compared to their male counterparts. The incidence in females is higher compared to men and it is sometimes erroneously considered as part of the post-menopausal period rather than hypertension. The impact of medications on sexual dysfunction has somewhat produced contrasting results with some studies showing an association with medications and others proving otherwise. Clinicians need to be aware of the impact of sexual dysfunction among hypertensive patients in order to make an informed decision regarding dosage and choice of medications while keeping target blood pressure in mind.

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 3, Issue 6)
DOI 10.11648/j.ijcems.20170306.15
Page(s) 87-94
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Erectile Dysfunction, Hypertension, Antihypertensive Medications, Sexual Dysfunction

References
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    Bright Boafo Boamah, Edward Kwaku Armah, Gifty Oppong Boakye. (2017). A Review on Erectile Dysfunction Among Hypertensive Patients on Pharmacotherapy. International Journal of Clinical and Experimental Medical Sciences, 3(6), 87-94. https://doi.org/10.11648/j.ijcems.20170306.15

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    Bright Boafo Boamah; Edward Kwaku Armah; Gifty Oppong Boakye. A Review on Erectile Dysfunction Among Hypertensive Patients on Pharmacotherapy. Int. J. Clin. Exp. Med. Sci. 2017, 3(6), 87-94. doi: 10.11648/j.ijcems.20170306.15

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    AMA Style

    Bright Boafo Boamah, Edward Kwaku Armah, Gifty Oppong Boakye. A Review on Erectile Dysfunction Among Hypertensive Patients on Pharmacotherapy. Int J Clin Exp Med Sci. 2017;3(6):87-94. doi: 10.11648/j.ijcems.20170306.15

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  • @article{10.11648/j.ijcems.20170306.15,
      author = {Bright Boafo Boamah and Edward Kwaku Armah and Gifty Oppong Boakye},
      title = {A Review on Erectile Dysfunction Among Hypertensive Patients on Pharmacotherapy},
      journal = {International Journal of Clinical and Experimental Medical Sciences},
      volume = {3},
      number = {6},
      pages = {87-94},
      doi = {10.11648/j.ijcems.20170306.15},
      url = {https://doi.org/10.11648/j.ijcems.20170306.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20170306.15},
      abstract = {Hypertension and its related disorders have a high mortality as well as morbidity and require strict adherence to medications in order to mitigate these consequences. Sexual dysfunction is prevalent among patients with hypertension and can either be attributed to the disease progression or as a result of antihypertensive medications. Most patients report the symptoms after initiation therapy and sometimes leads to a spurious association with antihypertensive drugs. However, most drugs in the antihypertensive classes have been associated with sexual dysfunction in both men and women. The most implicated drugs are diuretics, beta-blockers, and centrally acting agents while angiotensin modulating drugs have proved to improve upon erectile dysfunction. The older generation of antihypertensive medications tends to have a negative impact on sexual performance. Females experience sexual dysfunction associated with hypertension and its treatment, but this is grossly under-reported compared to their male counterparts. The incidence in females is higher compared to men and it is sometimes erroneously considered as part of the post-menopausal period rather than hypertension. The impact of medications on sexual dysfunction has somewhat produced contrasting results with some studies showing an association with medications and others proving otherwise. Clinicians need to be aware of the impact of sexual dysfunction among hypertensive patients in order to make an informed decision regarding dosage and choice of medications while keeping target blood pressure in mind.},
     year = {2017}
    }
    

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    AU  - Bright Boafo Boamah
    AU  - Edward Kwaku Armah
    AU  - Gifty Oppong Boakye
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    AB  - Hypertension and its related disorders have a high mortality as well as morbidity and require strict adherence to medications in order to mitigate these consequences. Sexual dysfunction is prevalent among patients with hypertension and can either be attributed to the disease progression or as a result of antihypertensive medications. Most patients report the symptoms after initiation therapy and sometimes leads to a spurious association with antihypertensive drugs. However, most drugs in the antihypertensive classes have been associated with sexual dysfunction in both men and women. The most implicated drugs are diuretics, beta-blockers, and centrally acting agents while angiotensin modulating drugs have proved to improve upon erectile dysfunction. The older generation of antihypertensive medications tends to have a negative impact on sexual performance. Females experience sexual dysfunction associated with hypertension and its treatment, but this is grossly under-reported compared to their male counterparts. The incidence in females is higher compared to men and it is sometimes erroneously considered as part of the post-menopausal period rather than hypertension. The impact of medications on sexual dysfunction has somewhat produced contrasting results with some studies showing an association with medications and others proving otherwise. Clinicians need to be aware of the impact of sexual dysfunction among hypertensive patients in order to make an informed decision regarding dosage and choice of medications while keeping target blood pressure in mind.
    VL  - 3
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Author Information
  • Department of Pharmacology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

  • Department of Chemical Engineering, Durban University of Technology, Durban, South Africa

  • Department of Mechanical Engineering, University of Leeds, Leeds, United Kingdom

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