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Socio-cultural Factors Influencing Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in a Tertiary Hospital in Southwestern Nigeria

Received: 22 August 2019    Accepted: 24 September 2019    Published: 8 November 2019
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Abstract

The study investigated the socio-cultural factors influencing adherence to antiretroviral drugs among people living with HIV in a University Teaching Hospital in South-western Nigeria. It investigated the influence of various socio-cultural factors on adherence of PLWHA to treatment regimen People Living with HIV/AIDS (PLWHA) of antiretroviral therapy (ART) in Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife and assessed the prevalence of adherence to ART among PLWHA in the study area. These were with the view to ascertaining the influence of socio-cultural factors in the PLWHA’s adherence to antiretroviral therapy in the study location. The study design was a cross-sectional where both qualitative and quantitative research methods were adopted. The quantitative data were collected using structured questionnaire. The participants were HIV diagnosed patients attending clinic at the Obafemi Awolowo University Teaching Hospitals Complex in Ile-Ife where ages were between 18 and 60 years. Also two focus group discussion sessions were held with 10 males and 10 females living with HIV and currently on ART. Furthermore, in-depth interviews were conducted on three purposively selected healthcare givers (an experienced nurse, a doctor and a pharmacist) in the clinic. The quantitative data were analyzed using descriptive statistics such as tables and percentages and inferential statistics such as Chi Square and cross-tabulations. The qualitative data were analyzed in themes based on the objectives. The findings from the study indicated level of adherence to ART was 89.0% among the respondents. There was a statistically significant relationship (χ2 = 22.14; p < 0.01) between social and family supports and the degree of adherence to ART among PLWHA. There was a statistically significant relationship between level of adherence and respondents’ age (χ2 = 66.05, p < 0.05). The older the respondents’ age, the higher the level of adherence to ART. Also the relationship between educational level and adherence to ART was explored and found to be statistically significant (χ2 = 26.04, p < 0.05). Adherence is inversely proportional to educational attainment. Nutrition, polygyny, difficulty in financing transportation fare to the clinic, unemployment, drug hawkers, religion, excuse duty from work and waking up very early were highlighted as socio-cultural barriers to adherence to ART. Fear of death, strong family support, religious belief, not seeking alternative treatment, absence of rituals and perceived improved health status were identified as very strong facilitators to adherence. The study concluded that socio-cultural factors exert very strong influences on PLWHA’s adherence to antiretroviral therapy.

Published in International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 5, Issue 2)
DOI 10.11648/j.ijhpebs.20190502.17
Page(s) 124-133
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antiretroviral Therapy, HIV/AIDS, Adherence, Socio-cultural

References
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[5] S. Wakibi, Z. Ng’ang’a, and G. Mbugua, “Factors associated with non-adherence to highly active antiretroviral therapy in Nairobi, Kenya,” AIDS Res. Ther., vol. 8, no. 43, pp. 1–8, 2011.
[6] T. F. F. Ferguson, K. E. S. Tewart, E. F. Unkhouser, J. T. Olson, A. O. W. Estfall, and M. S. S. Aag, “Patient-perceived barriers to antiretroviral adherence : associations with race,” AIDS Care, vol. 14, no. 5, pp. 607–617, 2002.
[7] D. R. Bangsberg et al., “Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population,” AIDS, vol. 14, pp. 357–366, 2000.
[8] S. A. Iacob, D. G. Iacob, and G. Jugulete, “Improving the adherence to antiretroviral therapy, a difficult but essential task for a successful HIV treatment-clinical points of view and practical considerations,” Front. Pharmacol., vol. 8, no. NOV, pp. 1–12, 2017.
[9] K. Peltzer, N. F. Preez, S. Ramlagan, and J. Anderson, “Antiretroviral treatment adherence among HIV patients in KwaZulu-Natal, South Africa,” BMC Public Health, vol. 10, no. 111, pp. 1–10, 2010.
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[16] C. Anyaike et al., “Adherence to combined antiretroviral therapy (cART) among people living with HIV/AIDS in a tertiary hospital in Ilorin, Nigeria,” Pan Afr. Med. J., vol. 32, no. 10, pp. 1–12, 2019.
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[19] S. P. Wasti, P. Simkhada, J. Randall, J. V Freeman, and E. Van Teijlingen, “Barriers to and Facilitators of Antiretroviral Therapy Adherence in Nepal : A Qualitative Study,” vol. 30, no. 4, pp. 410–419, 2012.
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    Okunola Oluseye Ademola, Muoghalu Caroline, Irinoye Adedayo Ishola. (2019). Socio-cultural Factors Influencing Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in a Tertiary Hospital in Southwestern Nigeria. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 5(2), 124-133. https://doi.org/10.11648/j.ijhpebs.20190502.17

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    ACS Style

    Okunola Oluseye Ademola; Muoghalu Caroline; Irinoye Adedayo Ishola. Socio-cultural Factors Influencing Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in a Tertiary Hospital in Southwestern Nigeria. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2019, 5(2), 124-133. doi: 10.11648/j.ijhpebs.20190502.17

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    AMA Style

    Okunola Oluseye Ademola, Muoghalu Caroline, Irinoye Adedayo Ishola. Socio-cultural Factors Influencing Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in a Tertiary Hospital in Southwestern Nigeria. Int J HIV/AIDS Prev Educ Behav Sci. 2019;5(2):124-133. doi: 10.11648/j.ijhpebs.20190502.17

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  • @article{10.11648/j.ijhpebs.20190502.17,
      author = {Okunola Oluseye Ademola and Muoghalu Caroline and Irinoye Adedayo Ishola},
      title = {Socio-cultural Factors Influencing Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in a Tertiary Hospital in Southwestern Nigeria},
      journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
      volume = {5},
      number = {2},
      pages = {124-133},
      doi = {10.11648/j.ijhpebs.20190502.17},
      url = {https://doi.org/10.11648/j.ijhpebs.20190502.17},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20190502.17},
      abstract = {The study investigated the socio-cultural factors influencing adherence to antiretroviral drugs among people living with HIV in a University Teaching Hospital in South-western Nigeria. It investigated the influence of various socio-cultural factors on adherence of PLWHA to treatment regimen People Living with HIV/AIDS (PLWHA) of antiretroviral therapy (ART) in Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife and assessed the prevalence of adherence to ART among PLWHA in the study area. These were with the view to ascertaining the influence of socio-cultural factors in the PLWHA’s adherence to antiretroviral therapy in the study location. The study design was a cross-sectional where both qualitative and quantitative research methods were adopted. The quantitative data were collected using structured questionnaire. The participants were HIV diagnosed patients attending clinic at the Obafemi Awolowo University Teaching Hospitals Complex in Ile-Ife where ages were between 18 and 60 years. Also two focus group discussion sessions were held with 10 males and 10 females living with HIV and currently on ART. Furthermore, in-depth interviews were conducted on three purposively selected healthcare givers (an experienced nurse, a doctor and a pharmacist) in the clinic. The quantitative data were analyzed using descriptive statistics such as tables and percentages and inferential statistics such as Chi Square and cross-tabulations. The qualitative data were analyzed in themes based on the objectives. The findings from the study indicated level of adherence to ART was 89.0% among the respondents. There was a statistically significant relationship (χ2 = 22.14; p 2 = 66.05, p 2 = 26.04, p < 0.05). Adherence is inversely proportional to educational attainment. Nutrition, polygyny, difficulty in financing transportation fare to the clinic, unemployment, drug hawkers, religion, excuse duty from work and waking up very early were highlighted as socio-cultural barriers to adherence to ART. Fear of death, strong family support, religious belief, not seeking alternative treatment, absence of rituals and perceived improved health status were identified as very strong facilitators to adherence. The study concluded that socio-cultural factors exert very strong influences on PLWHA’s adherence to antiretroviral therapy.},
     year = {2019}
    }
    

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    AU  - Okunola Oluseye Ademola
    AU  - Muoghalu Caroline
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    DO  - 10.11648/j.ijhpebs.20190502.17
    T2  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
    JF  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
    JO  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
    SP  - 124
    EP  - 133
    PB  - Science Publishing Group
    SN  - 2575-5765
    UR  - https://doi.org/10.11648/j.ijhpebs.20190502.17
    AB  - The study investigated the socio-cultural factors influencing adherence to antiretroviral drugs among people living with HIV in a University Teaching Hospital in South-western Nigeria. It investigated the influence of various socio-cultural factors on adherence of PLWHA to treatment regimen People Living with HIV/AIDS (PLWHA) of antiretroviral therapy (ART) in Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife and assessed the prevalence of adherence to ART among PLWHA in the study area. These were with the view to ascertaining the influence of socio-cultural factors in the PLWHA’s adherence to antiretroviral therapy in the study location. The study design was a cross-sectional where both qualitative and quantitative research methods were adopted. The quantitative data were collected using structured questionnaire. The participants were HIV diagnosed patients attending clinic at the Obafemi Awolowo University Teaching Hospitals Complex in Ile-Ife where ages were between 18 and 60 years. Also two focus group discussion sessions were held with 10 males and 10 females living with HIV and currently on ART. Furthermore, in-depth interviews were conducted on three purposively selected healthcare givers (an experienced nurse, a doctor and a pharmacist) in the clinic. The quantitative data were analyzed using descriptive statistics such as tables and percentages and inferential statistics such as Chi Square and cross-tabulations. The qualitative data were analyzed in themes based on the objectives. The findings from the study indicated level of adherence to ART was 89.0% among the respondents. There was a statistically significant relationship (χ2 = 22.14; p 2 = 66.05, p 2 = 26.04, p < 0.05). Adherence is inversely proportional to educational attainment. Nutrition, polygyny, difficulty in financing transportation fare to the clinic, unemployment, drug hawkers, religion, excuse duty from work and waking up very early were highlighted as socio-cultural barriers to adherence to ART. Fear of death, strong family support, religious belief, not seeking alternative treatment, absence of rituals and perceived improved health status were identified as very strong facilitators to adherence. The study concluded that socio-cultural factors exert very strong influences on PLWHA’s adherence to antiretroviral therapy.
    VL  - 5
    IS  - 2
    ER  - 

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Author Information
  • Sociology and Anthropology Department, Obafemi Awolowo University, Ile-Ife, Nigeria

  • Sociology and Anthropology Department, Obafemi Awolowo University, Ile-Ife, Nigeria

  • Medical and Health Services, Obafemi Awolowo University, Ile-Ife, Nigeria

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