Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria

Bountain Welcome Tebeda; Hannah Odunola Dada-Adegbola; Aishat Bukola Usman; Muhammad Shakir Balogun; Olufunmilayo Ibitola Fawole

doi:doi:10.11648/j.cajph.20200601.12

Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria

Bountain Welcome Tebeda, Hannah Odunola Dada-Adegbola, Aishat Bukola Usman, Muhammad Shakir Balogun, Olufunmilayo Ibitola Fawole

Published in Central African Journal of Public Health (Volume 6, Issue 1)

Received: 7 December 2019 Accepted: 20 December 2019 Published: 6 January 2020

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Abstract

People living with HIV/AIDS (PLWHA) are at risk of cardiovascular disease (CVD) morbidity and mortality linked to dyslipidaemia because of plasma lipids alterations. Understanding the magnitude of dyslipidaemia and its correlates is essential for the CVD risk reduction in this population. We conducted this study to determine the prevalence and types of dyslipidaemia, sociodemographic, lifestyle characteristics and selected comorbidities among PLWHA in Yenagoa, Southern Nigeria. This is a cross-sectional study among 278 PLWHA, aged 18 years and above receiving the HIV-laboratory services of the Federal Medical Centre, Yenagoa from March through April 2017. We collected respondents’ sociodemographic data, lifestyle characteristics and selected comorbidities using an interviewer-administered, semi-structured questionnaire adapted from the WHO STEPS instrument. We collected venous blood and assayed for Total Cholesterol (TC), Triglycerides (TG), and High-Density Lipoprotein Cholesterol (HDL-C) using Selectra ProS Chemistry Analyzer and calculated Low-Density Lipoprotein Cholesterol (LDL-C) with Friedewald formula. We measured height and weight and calculated for body mass index, and retrieved CD4+ T-cell count results from the HIV-laboratory workbook. We analyzed the data with Epi Info 7.2 and did a multivariable logistic regression analysis to identify factors associated with dyslipidaemia at 95% confidence level. Respondents mean age was 40.0±8.8 years, 104 (37.4%) were aged 35-44 years, 192 (69.1%) were females and 152 (54.7%) were married or living with a partner. The prevalence of dyslipidaemia was 48.6%. Seventy-six (27.3%) of the respondents had decreased HDL-C as the most prevalent type of dyslipidaemia. Those engaged in harmful alcohol intake were 26 (9.4%), smokers 28 (10.1%), hypertensive 52 (18.7%) while 244 (87.8%) were on antiretroviral therapy. Predictors of dyslipidaemia were age 45-64 years [AOR=2.43 (95%CI: 1.20-4.92)], being married or living with a partner [AOR=1.72 (95%CI: 1.01-2.91)] and being physically inactive and overweight or obese [POR=5.71 (95%CI: 1.76-18.51)]. This study showed that dyslipidaemia was common among the PLWHA in Yenagoa, Nigeria, with decreased HDL-C as the most prevalent type. Being older than 45 years, married or living with a partner or being physically inactive and overweight or obese appears to be the major predictors of dyslipidaemia. There is a need to sustain the lifestyle counselling and laboratory monitoring of lipids among the PLWHA in Yenagoa, Southern Nigeria.

Published in	Central African Journal of Public Health (Volume 6, Issue 1)
DOI	10.11648/j.cajph.20200601.12
Page(s)	5-12
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Dyslipidaemia, Hypercholesterolaemia, Hypertriglyceridaemia, Low-density Lipoprotein Cholesterol, High-Density Lipoprotein Cholesterol, HIV/AIDS

References

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Bountain Welcome Tebeda, Hannah Odunola Dada-Adegbola, Aishat Bukola Usman, Muhammad Shakir Balogun, Olufunmilayo Ibitola Fawole. (2020). Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria. Central African Journal of Public Health, 6(1), 5-12. https://doi.org/10.11648/j.cajph.20200601.12

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ACS Style

Bountain Welcome Tebeda; Hannah Odunola Dada-Adegbola; Aishat Bukola Usman; Muhammad Shakir Balogun; Olufunmilayo Ibitola Fawole. Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria. Cent. Afr. J. Public Health 2020, 6(1), 5-12. doi: 10.11648/j.cajph.20200601.12

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AMA Style

Bountain Welcome Tebeda, Hannah Odunola Dada-Adegbola, Aishat Bukola Usman, Muhammad Shakir Balogun, Olufunmilayo Ibitola Fawole. Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria. Cent Afr J Public Health. 2020;6(1):5-12. doi: 10.11648/j.cajph.20200601.12

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@article{10.11648/j.cajph.20200601.12,
  author = {Bountain Welcome Tebeda and Hannah Odunola Dada-Adegbola and Aishat Bukola Usman and Muhammad Shakir Balogun and Olufunmilayo Ibitola Fawole},
  title = {Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria},
  journal = {Central African Journal of Public Health},
  volume = {6},
  number = {1},
  pages = {5-12},
  doi = {10.11648/j.cajph.20200601.12},
  url = {https://doi.org/10.11648/j.cajph.20200601.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cajph.20200601.12},
  abstract = {People living with HIV/AIDS (PLWHA) are at risk of cardiovascular disease (CVD) morbidity and mortality linked to dyslipidaemia because of plasma lipids alterations. Understanding the magnitude of dyslipidaemia and its correlates is essential for the CVD risk reduction in this population. We conducted this study to determine the prevalence and types of dyslipidaemia, sociodemographic, lifestyle characteristics and selected comorbidities among PLWHA in Yenagoa, Southern Nigeria. This is a cross-sectional study among 278 PLWHA, aged 18 years and above receiving the HIV-laboratory services of the Federal Medical Centre, Yenagoa from March through April 2017. We collected respondents’ sociodemographic data, lifestyle characteristics and selected comorbidities using an interviewer-administered, semi-structured questionnaire adapted from the WHO STEPS instrument. We collected venous blood and assayed for Total Cholesterol (TC), Triglycerides (TG), and High-Density Lipoprotein Cholesterol (HDL-C) using Selectra ProS Chemistry Analyzer and calculated Low-Density Lipoprotein Cholesterol (LDL-C) with Friedewald formula. We measured height and weight and calculated for body mass index, and retrieved CD4+ T-cell count results from the HIV-laboratory workbook. We analyzed the data with Epi Info 7.2 and did a multivariable logistic regression analysis to identify factors associated with dyslipidaemia at 95% confidence level. Respondents mean age was 40.0±8.8 years, 104 (37.4%) were aged 35-44 years, 192 (69.1%) were females and 152 (54.7%) were married or living with a partner. The prevalence of dyslipidaemia was 48.6%. Seventy-six (27.3%) of the respondents had decreased HDL-C as the most prevalent type of dyslipidaemia. Those engaged in harmful alcohol intake were 26 (9.4%), smokers 28 (10.1%), hypertensive 52 (18.7%) while 244 (87.8%) were on antiretroviral therapy. Predictors of dyslipidaemia were age 45-64 years [AOR=2.43 (95%CI: 1.20-4.92)], being married or living with a partner [AOR=1.72 (95%CI: 1.01-2.91)] and being physically inactive and overweight or obese [POR=5.71 (95%CI: 1.76-18.51)]. This study showed that dyslipidaemia was common among the PLWHA in Yenagoa, Nigeria, with decreased HDL-C as the most prevalent type. Being older than 45 years, married or living with a partner or being physically inactive and overweight or obese appears to be the major predictors of dyslipidaemia. There is a need to sustain the lifestyle counselling and laboratory monitoring of lipids among the PLWHA in Yenagoa, Southern Nigeria.},
 year = {2020}
}

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TY  - JOUR
T1  - Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria
AU  - Bountain Welcome Tebeda
AU  - Hannah Odunola Dada-Adegbola
AU  - Aishat Bukola Usman
AU  - Muhammad Shakir Balogun
AU  - Olufunmilayo Ibitola Fawole
Y1  - 2020/01/06
PY  - 2020
N1  - https://doi.org/10.11648/j.cajph.20200601.12
DO  - 10.11648/j.cajph.20200601.12
T2  - Central African Journal of Public Health
JF  - Central African Journal of Public Health
JO  - Central African Journal of Public Health
SP  - 5
EP  - 12
PB  - Science Publishing Group
SN  - 2575-5781
UR  - https://doi.org/10.11648/j.cajph.20200601.12
AB  - People living with HIV/AIDS (PLWHA) are at risk of cardiovascular disease (CVD) morbidity and mortality linked to dyslipidaemia because of plasma lipids alterations. Understanding the magnitude of dyslipidaemia and its correlates is essential for the CVD risk reduction in this population. We conducted this study to determine the prevalence and types of dyslipidaemia, sociodemographic, lifestyle characteristics and selected comorbidities among PLWHA in Yenagoa, Southern Nigeria. This is a cross-sectional study among 278 PLWHA, aged 18 years and above receiving the HIV-laboratory services of the Federal Medical Centre, Yenagoa from March through April 2017. We collected respondents’ sociodemographic data, lifestyle characteristics and selected comorbidities using an interviewer-administered, semi-structured questionnaire adapted from the WHO STEPS instrument. We collected venous blood and assayed for Total Cholesterol (TC), Triglycerides (TG), and High-Density Lipoprotein Cholesterol (HDL-C) using Selectra ProS Chemistry Analyzer and calculated Low-Density Lipoprotein Cholesterol (LDL-C) with Friedewald formula. We measured height and weight and calculated for body mass index, and retrieved CD4+ T-cell count results from the HIV-laboratory workbook. We analyzed the data with Epi Info 7.2 and did a multivariable logistic regression analysis to identify factors associated with dyslipidaemia at 95% confidence level. Respondents mean age was 40.0±8.8 years, 104 (37.4%) were aged 35-44 years, 192 (69.1%) were females and 152 (54.7%) were married or living with a partner. The prevalence of dyslipidaemia was 48.6%. Seventy-six (27.3%) of the respondents had decreased HDL-C as the most prevalent type of dyslipidaemia. Those engaged in harmful alcohol intake were 26 (9.4%), smokers 28 (10.1%), hypertensive 52 (18.7%) while 244 (87.8%) were on antiretroviral therapy. Predictors of dyslipidaemia were age 45-64 years [AOR=2.43 (95%CI: 1.20-4.92)], being married or living with a partner [AOR=1.72 (95%CI: 1.01-2.91)] and being physically inactive and overweight or obese [POR=5.71 (95%CI: 1.76-18.51)]. This study showed that dyslipidaemia was common among the PLWHA in Yenagoa, Nigeria, with decreased HDL-C as the most prevalent type. Being older than 45 years, married or living with a partner or being physically inactive and overweight or obese appears to be the major predictors of dyslipidaemia. There is a need to sustain the lifestyle counselling and laboratory monitoring of lipids among the PLWHA in Yenagoa, Southern Nigeria.
VL  - 6
IS  - 1
ER  -

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Author Information

Bountain Welcome Tebeda

Nigeria Field Epidemiology and Laboratory Training Programme, Abuja, Nigeria;African Field Epidemiology Network, Abuja, Nigeria
Hannah Odunola Dada-Adegbola

Department of Medical Microbiology and Parasitology, College of Medicine, University of Ibadan, Ibadan, Nigeria
Aishat Bukola Usman

African Field Epidemiology Network, Abuja, Nigeria
Muhammad Shakir Balogun

Nigeria Field Epidemiology and Laboratory Training Programme, Abuja, Nigeria;African Field Epidemiology Network, Abuja, Nigeria
Olufunmilayo Ibitola Fawole

Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria

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Bountain Welcome Tebeda, Hannah Odunola Dada-Adegbola, Aishat Bukola Usman, Muhammad Shakir Balogun, Olufunmilayo Ibitola Fawole. (2020). Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria. Central African Journal of Public Health, 6(1), 5-12. https://doi.org/10.11648/j.cajph.20200601.12

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ACS Style

Bountain Welcome Tebeda; Hannah Odunola Dada-Adegbola; Aishat Bukola Usman; Muhammad Shakir Balogun; Olufunmilayo Ibitola Fawole. Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria. Cent. Afr. J. Public Health 2020, 6(1), 5-12. doi: 10.11648/j.cajph.20200601.12

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AMA Style

Bountain Welcome Tebeda, Hannah Odunola Dada-Adegbola, Aishat Bukola Usman, Muhammad Shakir Balogun, Olufunmilayo Ibitola Fawole. Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria. Cent Afr J Public Health. 2020;6(1):5-12. doi: 10.11648/j.cajph.20200601.12

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@article{10.11648/j.cajph.20200601.12,
  author = {Bountain Welcome Tebeda and Hannah Odunola Dada-Adegbola and Aishat Bukola Usman and Muhammad Shakir Balogun and Olufunmilayo Ibitola Fawole},
  title = {Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria},
  journal = {Central African Journal of Public Health},
  volume = {6},
  number = {1},
  pages = {5-12},
  doi = {10.11648/j.cajph.20200601.12},
  url = {https://doi.org/10.11648/j.cajph.20200601.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cajph.20200601.12},
  abstract = {People living with HIV/AIDS (PLWHA) are at risk of cardiovascular disease (CVD) morbidity and mortality linked to dyslipidaemia because of plasma lipids alterations. Understanding the magnitude of dyslipidaemia and its correlates is essential for the CVD risk reduction in this population. We conducted this study to determine the prevalence and types of dyslipidaemia, sociodemographic, lifestyle characteristics and selected comorbidities among PLWHA in Yenagoa, Southern Nigeria. This is a cross-sectional study among 278 PLWHA, aged 18 years and above receiving the HIV-laboratory services of the Federal Medical Centre, Yenagoa from March through April 2017. We collected respondents’ sociodemographic data, lifestyle characteristics and selected comorbidities using an interviewer-administered, semi-structured questionnaire adapted from the WHO STEPS instrument. We collected venous blood and assayed for Total Cholesterol (TC), Triglycerides (TG), and High-Density Lipoprotein Cholesterol (HDL-C) using Selectra ProS Chemistry Analyzer and calculated Low-Density Lipoprotein Cholesterol (LDL-C) with Friedewald formula. We measured height and weight and calculated for body mass index, and retrieved CD4+ T-cell count results from the HIV-laboratory workbook. We analyzed the data with Epi Info 7.2 and did a multivariable logistic regression analysis to identify factors associated with dyslipidaemia at 95% confidence level. Respondents mean age was 40.0±8.8 years, 104 (37.4%) were aged 35-44 years, 192 (69.1%) were females and 152 (54.7%) were married or living with a partner. The prevalence of dyslipidaemia was 48.6%. Seventy-six (27.3%) of the respondents had decreased HDL-C as the most prevalent type of dyslipidaemia. Those engaged in harmful alcohol intake were 26 (9.4%), smokers 28 (10.1%), hypertensive 52 (18.7%) while 244 (87.8%) were on antiretroviral therapy. Predictors of dyslipidaemia were age 45-64 years [AOR=2.43 (95%CI: 1.20-4.92)], being married or living with a partner [AOR=1.72 (95%CI: 1.01-2.91)] and being physically inactive and overweight or obese [POR=5.71 (95%CI: 1.76-18.51)]. This study showed that dyslipidaemia was common among the PLWHA in Yenagoa, Nigeria, with decreased HDL-C as the most prevalent type. Being older than 45 years, married or living with a partner or being physically inactive and overweight or obese appears to be the major predictors of dyslipidaemia. There is a need to sustain the lifestyle counselling and laboratory monitoring of lipids among the PLWHA in Yenagoa, Southern Nigeria.},
 year = {2020}
}

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TY  - JOUR
T1  - Dyslipidaemia and Its Correlates Among People Living with Human Immunodeficiency Virus in Yenagoa, Southern Nigeria
AU  - Bountain Welcome Tebeda
AU  - Hannah Odunola Dada-Adegbola
AU  - Aishat Bukola Usman
AU  - Muhammad Shakir Balogun
AU  - Olufunmilayo Ibitola Fawole
Y1  - 2020/01/06
PY  - 2020
N1  - https://doi.org/10.11648/j.cajph.20200601.12
DO  - 10.11648/j.cajph.20200601.12
T2  - Central African Journal of Public Health
JF  - Central African Journal of Public Health
JO  - Central African Journal of Public Health
SP  - 5
EP  - 12
PB  - Science Publishing Group
SN  - 2575-5781
UR  - https://doi.org/10.11648/j.cajph.20200601.12
AB  - People living with HIV/AIDS (PLWHA) are at risk of cardiovascular disease (CVD) morbidity and mortality linked to dyslipidaemia because of plasma lipids alterations. Understanding the magnitude of dyslipidaemia and its correlates is essential for the CVD risk reduction in this population. We conducted this study to determine the prevalence and types of dyslipidaemia, sociodemographic, lifestyle characteristics and selected comorbidities among PLWHA in Yenagoa, Southern Nigeria. This is a cross-sectional study among 278 PLWHA, aged 18 years and above receiving the HIV-laboratory services of the Federal Medical Centre, Yenagoa from March through April 2017. We collected respondents’ sociodemographic data, lifestyle characteristics and selected comorbidities using an interviewer-administered, semi-structured questionnaire adapted from the WHO STEPS instrument. We collected venous blood and assayed for Total Cholesterol (TC), Triglycerides (TG), and High-Density Lipoprotein Cholesterol (HDL-C) using Selectra ProS Chemistry Analyzer and calculated Low-Density Lipoprotein Cholesterol (LDL-C) with Friedewald formula. We measured height and weight and calculated for body mass index, and retrieved CD4+ T-cell count results from the HIV-laboratory workbook. We analyzed the data with Epi Info 7.2 and did a multivariable logistic regression analysis to identify factors associated with dyslipidaemia at 95% confidence level. Respondents mean age was 40.0±8.8 years, 104 (37.4%) were aged 35-44 years, 192 (69.1%) were females and 152 (54.7%) were married or living with a partner. The prevalence of dyslipidaemia was 48.6%. Seventy-six (27.3%) of the respondents had decreased HDL-C as the most prevalent type of dyslipidaemia. Those engaged in harmful alcohol intake were 26 (9.4%), smokers 28 (10.1%), hypertensive 52 (18.7%) while 244 (87.8%) were on antiretroviral therapy. Predictors of dyslipidaemia were age 45-64 years [AOR=2.43 (95%CI: 1.20-4.92)], being married or living with a partner [AOR=1.72 (95%CI: 1.01-2.91)] and being physically inactive and overweight or obese [POR=5.71 (95%CI: 1.76-18.51)]. This study showed that dyslipidaemia was common among the PLWHA in Yenagoa, Nigeria, with decreased HDL-C as the most prevalent type. Being older than 45 years, married or living with a partner or being physically inactive and overweight or obese appears to be the major predictors of dyslipidaemia. There is a need to sustain the lifestyle counselling and laboratory monitoring of lipids among the PLWHA in Yenagoa, Southern Nigeria.
VL  - 6
IS  - 1
ER  -

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