Statistical Aspects of the Interrelation Between the Biological Activity of Chemical Compounds and Their Molecular Structure
Biomedical Statistics and Informatics
Volume 1, Issue 1, December 2016, Pages: 24-34
Received: Dec. 7, 2016;
Accepted: Dec. 27, 2016;
Published: Jan. 20, 2017
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Mukhomorov V. K., Universita Degli Studi di Napoli “Federico II”, Via Cintia, Napoli, Italy
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An attempt was made to construct an adequate model of interrelation of radioprotective properties of biologically active chemical compounds with their electronic and information factors. Biological activity (radiation protective effects) of chemical compounds has been analyzed in relation to their electronic sign and the information function. Statistical comparison of qualitative indices has revealed that electronic and information signs the most informative characteristics of the molecules responsible for radiation protective action. Correlation equations are given for electronic and information dependent change in the antiradiation properties of the molecule. Quantitative estimates were made associating the protective efficiency of the chemical compounds under study with variations in the electronic parameters and dose of chemicals.
Bioactivity, Statistics, Molecular Structure, Electronic Sign, Information Function, Radioprotector, Statistical Criterion, Contingency, Correlation
To cite this article
Mukhomorov V. K.,
Statistical Aspects of the Interrelation Between the Biological Activity of Chemical Compounds and Their Molecular Structure, Biomedical Statistics and Informatics.
Vol. 1, No. 1,
2016, pp. 24-34.
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
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