International Journal of Clinical Oncology and Cancer Research

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Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women

Received: 28 March 2019    Accepted: 05 May 2019    Published: 30 May 2019
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Abstract

The objective of this study is to show that the presence of koilocytosis on the cervical smear is the only possibility to detect Papillomavirus infection in cervical intra-epithelial neoplasia in women living in Lubumbashi. This is a cross-sectional analytical study on the data collected from the register of women who participated in the cervix lesion screening campaign organized in Lubumbashi in March 2012 by the Congolese League Against Cancer. A total of 545 women with cervical lesions have been selected. The following results were observed: the frequency of HPV infection is 35% in Lubumbashi women. The risk of developing intraepithelial neoplasia is 38.3 times higher in women infected with HPV compared to uninfected ones (OR = 38.3, 95% CI = 16.3-90.3). HPV is predominantly present in intraepithelial neoplasia (92.7%) and this regardless of their grade: 91.9% for low-grade neoplasia and 95% for high-grade neoplasia. HPV is found in both older women and older women, respectively in 45% of women aged less than 36 years and in 55% of women aged over 36 years old. This study shows that it is necessary to put in place adequate means for the detection of HPV in order to contribute to the fight against cervical cancer in Lubumbashi.

DOI 10.11648/j.ijcocr.20190401.11
Published in International Journal of Clinical Oncology and Cancer Research (Volume 4, Issue 1, February 2019)
Page(s) 1-4
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Papillomavirus, Intra Epithelial Neoplasia, Cervix, Lubumbashi

References
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Author Information
  • Pathology Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Pathology Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Public Health Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Public Health Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Gynecology Obstetrics Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Gynecology Obstetrics Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Pathology Department, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

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    Mwenze Didier, Kyabu Véronique, Mulenga Philippe, Mukalay Abdon, Chola Joseph, et al. (2019). Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women. International Journal of Clinical Oncology and Cancer Research, 4(1), 1-4. https://doi.org/10.11648/j.ijcocr.20190401.11

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    ACS Style

    Mwenze Didier; Kyabu Véronique; Mulenga Philippe; Mukalay Abdon; Chola Joseph, et al. Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women. Int. J. Clin. Oncol. Cancer Res. 2019, 4(1), 1-4. doi: 10.11648/j.ijcocr.20190401.11

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    AMA Style

    Mwenze Didier, Kyabu Véronique, Mulenga Philippe, Mukalay Abdon, Chola Joseph, et al. Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women. Int J Clin Oncol Cancer Res. 2019;4(1):1-4. doi: 10.11648/j.ijcocr.20190401.11

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  • @article{10.11648/j.ijcocr.20190401.11,
      author = {Mwenze Didier and Kyabu Véronique and Mulenga Philippe and Mukalay Abdon and Chola Joseph and Kalenga Prosper and Ilunga Julien},
      title = {Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women},
      journal = {International Journal of Clinical Oncology and Cancer Research},
      volume = {4},
      number = {1},
      pages = {1-4},
      doi = {10.11648/j.ijcocr.20190401.11},
      url = {https://doi.org/10.11648/j.ijcocr.20190401.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijcocr.20190401.11},
      abstract = {The objective of this study is to show that the presence of koilocytosis on the cervical smear is the only possibility to detect Papillomavirus infection in cervical intra-epithelial neoplasia in women living in Lubumbashi. This is a cross-sectional analytical study on the data collected from the register of women who participated in the cervix lesion screening campaign organized in Lubumbashi in March 2012 by the Congolese League Against Cancer. A total of 545 women with cervical lesions have been selected. The following results were observed: the frequency of HPV infection is 35% in Lubumbashi women. The risk of developing intraepithelial neoplasia is 38.3 times higher in women infected with HPV compared to uninfected ones (OR = 38.3, 95% CI = 16.3-90.3). HPV is predominantly present in intraepithelial neoplasia (92.7%) and this regardless of their grade: 91.9% for low-grade neoplasia and 95% for high-grade neoplasia. HPV is found in both older women and older women, respectively in 45% of women aged less than 36 years and in 55% of women aged over 36 years old. This study shows that it is necessary to put in place adequate means for the detection of HPV in order to contribute to the fight against cervical cancer in Lubumbashi.},
     year = {2019}
    }
    

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    T1  - Human Papillomavirus and Cervical Intra-Epithelial Neoplasia: Epidemiological and Cytological Study in Lubumbashi Women
    AU  - Mwenze Didier
    AU  - Kyabu Véronique
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    JF  - International Journal of Clinical Oncology and Cancer Research
    JO  - International Journal of Clinical Oncology and Cancer Research
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    AB  - The objective of this study is to show that the presence of koilocytosis on the cervical smear is the only possibility to detect Papillomavirus infection in cervical intra-epithelial neoplasia in women living in Lubumbashi. This is a cross-sectional analytical study on the data collected from the register of women who participated in the cervix lesion screening campaign organized in Lubumbashi in March 2012 by the Congolese League Against Cancer. A total of 545 women with cervical lesions have been selected. The following results were observed: the frequency of HPV infection is 35% in Lubumbashi women. The risk of developing intraepithelial neoplasia is 38.3 times higher in women infected with HPV compared to uninfected ones (OR = 38.3, 95% CI = 16.3-90.3). HPV is predominantly present in intraepithelial neoplasia (92.7%) and this regardless of their grade: 91.9% for low-grade neoplasia and 95% for high-grade neoplasia. HPV is found in both older women and older women, respectively in 45% of women aged less than 36 years and in 55% of women aged over 36 years old. This study shows that it is necessary to put in place adequate means for the detection of HPV in order to contribute to the fight against cervical cancer in Lubumbashi.
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