International Journal of Clinical Oncology and Cancer Research

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Study of Serum Levels of Trace Elements (Selenium, Copper, Zinc, and Iron) in Breast Cancer Patients

Received: 02 July 2017    Accepted: 13 July 2017    Published: 15 August 2017
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Abstract

Purpose: Malignancy of the breast is one of the commonest causes of death in women aged between 40-45 years. The aim of this study was to carry out a comparative study to investigate the effect of minerals on the risk of a woman developing breast cancer. Materials and methods: Three hundred blood samples were used to analyze the status of concentration of Selenium (Se), Copper (Cu), Zinc (Zn) and Iron (Fe) in breast cancer (BC) patients and healthy individuals by using atomic absorption spectrophotometer. Results: There was a significant (p<0.05) decline in the concentration of Se in serum samples of BC patients as on comparison with the healthy individuals. Concentration of Cu of BC patients was increased significantly (p<0.05) on comparison with the healthy individuals. There was a significant (p<0.05) decline in the concentration of Zn in BC patients on comparison with the healthy individuals. Level of difference of Fe remain insignificant (p>0.05) in serum of BC patients. There was a significant decline in the concentration of Se and Zn while high level of serum copper in breast cancer patients, as compared with normal healthy controls. Conclusion: We found a significant association between trace elements (serum selenium, zinc and copper) with breast cancer.

DOI 10.11648/j.ijcocr.20170204.12
Published in International Journal of Clinical Oncology and Cancer Research (Volume 2, Issue 4, August 2017)
Page(s) 82-85
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Breast Cancer (BC), Serum Minerals, Selenium (Se), Copper (Cu), Zinc (Zn) and Iron (Fe)

References
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Author Information
  • Department of Biochemistry, Govt. Medical College, Srinagar, India

  • Registrar Academics, Govt. Medical College, Srinagar, India

  • Department of Biochemistry, Govt. Medical College, Srinagar, India

  • Department of Biochemistry, Govt. Medical College, Srinagar, India

  • Division of Vety. Biochemistry, Faculty of Veterinary Sciences, & Animal Husbandry, SKAUST-K, Shuhama, Srinagar, India

  • Director Research, Bhagwant University, Sikar Road Ajmer, Rajasthan, India

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  • APA Style

    Tehseen Hassan, Wasim Qureshi, Showkat Ahmad Bhat, Sabhiya Majid, Manzoor R. Mir, et al. (2017). Study of Serum Levels of Trace Elements (Selenium, Copper, Zinc, and Iron) in Breast Cancer Patients. International Journal of Clinical Oncology and Cancer Research, 2(4), 82-85. https://doi.org/10.11648/j.ijcocr.20170204.12

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    ACS Style

    Tehseen Hassan; Wasim Qureshi; Showkat Ahmad Bhat; Sabhiya Majid; Manzoor R. Mir, et al. Study of Serum Levels of Trace Elements (Selenium, Copper, Zinc, and Iron) in Breast Cancer Patients. Int. J. Clin. Oncol. Cancer Res. 2017, 2(4), 82-85. doi: 10.11648/j.ijcocr.20170204.12

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    AMA Style

    Tehseen Hassan, Wasim Qureshi, Showkat Ahmad Bhat, Sabhiya Majid, Manzoor R. Mir, et al. Study of Serum Levels of Trace Elements (Selenium, Copper, Zinc, and Iron) in Breast Cancer Patients. Int J Clin Oncol Cancer Res. 2017;2(4):82-85. doi: 10.11648/j.ijcocr.20170204.12

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  • @article{10.11648/j.ijcocr.20170204.12,
      author = {Tehseen Hassan and Wasim Qureshi and Showkat Ahmad Bhat and Sabhiya Majid and Manzoor R. Mir and Purnima Shrivastava},
      title = {Study of Serum Levels of Trace Elements (Selenium, Copper, Zinc, and Iron) in Breast Cancer Patients},
      journal = {International Journal of Clinical Oncology and Cancer Research},
      volume = {2},
      number = {4},
      pages = {82-85},
      doi = {10.11648/j.ijcocr.20170204.12},
      url = {https://doi.org/10.11648/j.ijcocr.20170204.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijcocr.20170204.12},
      abstract = {Purpose: Malignancy of the breast is one of the commonest causes of death in women aged between 40-45 years. The aim of this study was to carry out a comparative study to investigate the effect of minerals on the risk of a woman developing breast cancer. Materials and methods: Three hundred blood samples were used to analyze the status of concentration of Selenium (Se), Copper (Cu), Zinc (Zn) and Iron (Fe) in breast cancer (BC) patients and healthy individuals by using atomic absorption spectrophotometer. Results: There was a significant (p0.05) in serum of BC patients. There was a significant decline in the concentration of Se and Zn while high level of serum copper in breast cancer patients, as compared with normal healthy controls. Conclusion: We found a significant association between trace elements (serum selenium, zinc and copper) with breast cancer.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Study of Serum Levels of Trace Elements (Selenium, Copper, Zinc, and Iron) in Breast Cancer Patients
    AU  - Tehseen Hassan
    AU  - Wasim Qureshi
    AU  - Showkat Ahmad Bhat
    AU  - Sabhiya Majid
    AU  - Manzoor R. Mir
    AU  - Purnima Shrivastava
    Y1  - 2017/08/15
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ijcocr.20170204.12
    DO  - 10.11648/j.ijcocr.20170204.12
    T2  - International Journal of Clinical Oncology and Cancer Research
    JF  - International Journal of Clinical Oncology and Cancer Research
    JO  - International Journal of Clinical Oncology and Cancer Research
    SP  - 82
    EP  - 85
    PB  - Science Publishing Group
    SN  - 2578-9511
    UR  - https://doi.org/10.11648/j.ijcocr.20170204.12
    AB  - Purpose: Malignancy of the breast is one of the commonest causes of death in women aged between 40-45 years. The aim of this study was to carry out a comparative study to investigate the effect of minerals on the risk of a woman developing breast cancer. Materials and methods: Three hundred blood samples were used to analyze the status of concentration of Selenium (Se), Copper (Cu), Zinc (Zn) and Iron (Fe) in breast cancer (BC) patients and healthy individuals by using atomic absorption spectrophotometer. Results: There was a significant (p0.05) in serum of BC patients. There was a significant decline in the concentration of Se and Zn while high level of serum copper in breast cancer patients, as compared with normal healthy controls. Conclusion: We found a significant association between trace elements (serum selenium, zinc and copper) with breast cancer.
    VL  - 2
    IS  - 4
    ER  - 

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