International Journal of Clinical Oncology and Cancer Research

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The Relationship Between Sarcopenia and Cancer Chemotherapys

Received: 19 January 2020    Accepted: 30 March 2020    Published: 14 April 2020
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Abstract

As an independent disease, characterized by progressive and generalized loss of skeletal muscle mass, quality and strength, Sarcopenia has become a research hotspot in recent years, and its position in cancer patients has been increasingly valued by clinicians. Clarifying the relationship between Sarcopenia and chemotherapeutics in the treatment of cancer patients will help to formulate interventions for Sarcopenia to improve the quality of life and prolong survival period of cancer patients. In order to understand the relationship between Sarcopenia and cancer chemotherapy, we review from the following aspects. How is Sarcopenia diagnosed in cancer patients? How to evaluate Sarcopenia in cancer patients? What is the incidence of Sarcopenia in cancer patients? What is the relationship between the changes in body composition and the dose of chemotherapy in cancer patients? Whether there is a relationship between Sarcopenia and chemotherapy-related toxicity in cancer patients? Its role in leading to chemotherapy toxicity and its effect on the prognosis and survival in cancer patients. Whether chemotherapeutic drugs have an effect on the development of Sarcopenia in cancer patients, or whether certain types of chemotherapy drugs will affect Sarcopenia? Finally, the review also aims to describe interventions for Sarcopenia and their impact on the outcome of treatment for cancer patients.

DOI 10.11648/j.ijcocr.20200501.13
Published in International Journal of Clinical Oncology and Cancer Research (Volume 5, Issue 1, March 2020)
Page(s) 10-15
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Sarcopenia, Cancer Chemotherapy, Toxicity, Prognosis

References
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Author Information
  • Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China; Department of General Medicine, Xiangya Hospital, Central South University, Changsha, China

  • Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China

  • Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China

  • Department of Emergency, Xiangya Hospital, Central South University, Changsha, China

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  • APA Style

    Fufeng Zhang, Shasha Yang, Qiong Chen, Xiaoqin Lu. (2020). The Relationship Between Sarcopenia and Cancer Chemotherapys. International Journal of Clinical Oncology and Cancer Research, 5(1), 10-15. https://doi.org/10.11648/j.ijcocr.20200501.13

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    ACS Style

    Fufeng Zhang; Shasha Yang; Qiong Chen; Xiaoqin Lu. The Relationship Between Sarcopenia and Cancer Chemotherapys. Int. J. Clin. Oncol. Cancer Res. 2020, 5(1), 10-15. doi: 10.11648/j.ijcocr.20200501.13

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    AMA Style

    Fufeng Zhang, Shasha Yang, Qiong Chen, Xiaoqin Lu. The Relationship Between Sarcopenia and Cancer Chemotherapys. Int J Clin Oncol Cancer Res. 2020;5(1):10-15. doi: 10.11648/j.ijcocr.20200501.13

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  • @article{10.11648/j.ijcocr.20200501.13,
      author = {Fufeng Zhang and Shasha Yang and Qiong Chen and Xiaoqin Lu},
      title = {The Relationship Between Sarcopenia and Cancer Chemotherapys},
      journal = {International Journal of Clinical Oncology and Cancer Research},
      volume = {5},
      number = {1},
      pages = {10-15},
      doi = {10.11648/j.ijcocr.20200501.13},
      url = {https://doi.org/10.11648/j.ijcocr.20200501.13},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijcocr.20200501.13},
      abstract = {As an independent disease, characterized by progressive and generalized loss of skeletal muscle mass, quality and strength, Sarcopenia has become a research hotspot in recent years, and its position in cancer patients has been increasingly valued by clinicians. Clarifying the relationship between Sarcopenia and chemotherapeutics in the treatment of cancer patients will help to formulate interventions for Sarcopenia to improve the quality of life and prolong survival period of cancer patients. In order to understand the relationship between Sarcopenia and cancer chemotherapy, we review from the following aspects. How is Sarcopenia diagnosed in cancer patients? How to evaluate Sarcopenia in cancer patients? What is the incidence of Sarcopenia in cancer patients? What is the relationship between the changes in body composition and the dose of chemotherapy in cancer patients? Whether there is a relationship between Sarcopenia and chemotherapy-related toxicity in cancer patients? Its role in leading to chemotherapy toxicity and its effect on the prognosis and survival in cancer patients. Whether chemotherapeutic drugs have an effect on the development of Sarcopenia in cancer patients, or whether certain types of chemotherapy drugs will affect Sarcopenia? Finally, the review also aims to describe interventions for Sarcopenia and their impact on the outcome of treatment for cancer patients.},
     year = {2020}
    }
    

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    AU  - Fufeng Zhang
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    AU  - Qiong Chen
    AU  - Xiaoqin Lu
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    DO  - 10.11648/j.ijcocr.20200501.13
    T2  - International Journal of Clinical Oncology and Cancer Research
    JF  - International Journal of Clinical Oncology and Cancer Research
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    AB  - As an independent disease, characterized by progressive and generalized loss of skeletal muscle mass, quality and strength, Sarcopenia has become a research hotspot in recent years, and its position in cancer patients has been increasingly valued by clinicians. Clarifying the relationship between Sarcopenia and chemotherapeutics in the treatment of cancer patients will help to formulate interventions for Sarcopenia to improve the quality of life and prolong survival period of cancer patients. In order to understand the relationship between Sarcopenia and cancer chemotherapy, we review from the following aspects. How is Sarcopenia diagnosed in cancer patients? How to evaluate Sarcopenia in cancer patients? What is the incidence of Sarcopenia in cancer patients? What is the relationship between the changes in body composition and the dose of chemotherapy in cancer patients? Whether there is a relationship between Sarcopenia and chemotherapy-related toxicity in cancer patients? Its role in leading to chemotherapy toxicity and its effect on the prognosis and survival in cancer patients. Whether chemotherapeutic drugs have an effect on the development of Sarcopenia in cancer patients, or whether certain types of chemotherapy drugs will affect Sarcopenia? Finally, the review also aims to describe interventions for Sarcopenia and their impact on the outcome of treatment for cancer patients.
    VL  - 5
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