Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian
Clinical Neurology and Neuroscience
Volume 2, Issue 2, June 2018, Pages: 23-26
Received: Oct. 25, 2017;
Accepted: Feb. 3, 2018;
Published: Jul. 4, 2018
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Olusegun Adesola Busari, Department of Medicine, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria
Paul Olowoyo, Department of Medicine, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria
Segun Oladele Adeniyi, Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria
Bidemi Olayemi Onipede, Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria
Olisa Joseph, Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria
Solomon Ogunniran, Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria
Dopa-responsive dystonia, also known as hereditary progressive dystonia with diurnal variation, is a genetic disease characterized by childhood or adolescent onset of dystonia and sometimes associated with parkinsonian features. This is a case report of an 18 year old Nigerian University undergraduate with features of difficulty in speaking, stiffness of the body, gait difficulties, coarse tremors and toe-walking. There was a very marked improvement of symptoms and signs within 24-48 hours of the commencement of SinemetTM (levodopa/ carbidopa) 125mg/12.5mg daily. The patient was discharged after 5 days with normal gait.
Olusegun Adesola Busari,
Segun Oladele Adeniyi,
Bidemi Olayemi Onipede,
Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian, Clinical Neurology and Neuroscience.
Vol. 2, No. 2,
2018, pp. 23-26.
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