Clinical Neurology and Neuroscience

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Promise of Autologous Bone Marrow Stem Cell Transplantation to Patients with Spinal Cord Injury-Current Status

Received: 1 April 2017    Accepted: 12 May 2017    Published: 30 August 2017
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Abstract

Due to rapid industrialization, population raise and development of real estate business results to build of enormous constructions, which leads to the injuries of spinal cord. The burden of spinal cord injury induced limb paralysis increasing every year in India. Increasing vehicular traffic has caused numerous road traffic accidents. Spinal cord injury (SCI) affects all aspects of a patient’s life, including the physical, behavioral, psychological and social functioning. [1] Spinal cord injuries could not be treated effectively with the existing treatment modalities. In view of the above, there is definitely an urgent need for finding different methods of treatment for these patients who cannot undergo established modalities of treatment or these have been tried unsuccessfully. Since a large number of these patients will loose their productive life and at the prime of their lives one such alternate therapy, which seems to offer some promise, is “stem cell” therapy, which has been well studied and published in prestigious journals. Current review discuss the safety and therapeutic efficacy of autologous human bone marrow cell (BMC) transplantation and the administration of granulocyte macrophage-colony stimulating factor (GM-CSF).

DOI 10.11648/j.cnn.20170104.13
Published in Clinical Neurology and Neuroscience (Volume 1, Issue 4, November 2017)
Page(s) 84-95
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Bone Marrow Stem Cell, American Spinal Injury Association Scale, Granulocyte Macrophage-Colony Stimulating Factor

References
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    Mahaboob Vali Shaik, Subrahmanyam Gangapatnam. (2017). Promise of Autologous Bone Marrow Stem Cell Transplantation to Patients with Spinal Cord Injury-Current Status. Clinical Neurology and Neuroscience, 1(4), 84-95. https://doi.org/10.11648/j.cnn.20170104.13

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    Mahaboob Vali Shaik; Subrahmanyam Gangapatnam. Promise of Autologous Bone Marrow Stem Cell Transplantation to Patients with Spinal Cord Injury-Current Status. Clin. Neurol. Neurosci. 2017, 1(4), 84-95. doi: 10.11648/j.cnn.20170104.13

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    Mahaboob Vali Shaik, Subrahmanyam Gangapatnam. Promise of Autologous Bone Marrow Stem Cell Transplantation to Patients with Spinal Cord Injury-Current Status. Clin Neurol Neurosci. 2017;1(4):84-95. doi: 10.11648/j.cnn.20170104.13

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  • @article{10.11648/j.cnn.20170104.13,
      author = {Mahaboob Vali Shaik and Subrahmanyam Gangapatnam},
      title = {Promise of Autologous Bone Marrow Stem Cell Transplantation to Patients with Spinal Cord Injury-Current Status},
      journal = {Clinical Neurology and Neuroscience},
      volume = {1},
      number = {4},
      pages = {84-95},
      doi = {10.11648/j.cnn.20170104.13},
      url = {https://doi.org/10.11648/j.cnn.20170104.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20170104.13},
      abstract = {Due to rapid industrialization, population raise and development of real estate business results to build of enormous constructions, which leads to the injuries of spinal cord. The burden of spinal cord injury induced limb paralysis increasing every year in India. Increasing vehicular traffic has caused numerous road traffic accidents. Spinal cord injury (SCI) affects all aspects of a patient’s life, including the physical, behavioral, psychological and social functioning. [1] Spinal cord injuries could not be treated effectively with the existing treatment modalities. In view of the above, there is definitely an urgent need for finding different methods of treatment for these patients who cannot undergo established modalities of treatment or these have been tried unsuccessfully. Since a large number of these patients will loose their productive life and at the prime of their lives one such alternate therapy, which seems to offer some promise, is “stem cell” therapy, which has been well studied and published in prestigious journals. Current review discuss the safety and therapeutic efficacy of autologous human bone marrow cell (BMC) transplantation and the administration of granulocyte macrophage-colony stimulating factor (GM-CSF).},
     year = {2017}
    }
    

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    T1  - Promise of Autologous Bone Marrow Stem Cell Transplantation to Patients with Spinal Cord Injury-Current Status
    AU  - Mahaboob Vali Shaik
    AU  - Subrahmanyam Gangapatnam
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    N1  - https://doi.org/10.11648/j.cnn.20170104.13
    DO  - 10.11648/j.cnn.20170104.13
    T2  - Clinical Neurology and Neuroscience
    JF  - Clinical Neurology and Neuroscience
    JO  - Clinical Neurology and Neuroscience
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    AB  - Due to rapid industrialization, population raise and development of real estate business results to build of enormous constructions, which leads to the injuries of spinal cord. The burden of spinal cord injury induced limb paralysis increasing every year in India. Increasing vehicular traffic has caused numerous road traffic accidents. Spinal cord injury (SCI) affects all aspects of a patient’s life, including the physical, behavioral, psychological and social functioning. [1] Spinal cord injuries could not be treated effectively with the existing treatment modalities. In view of the above, there is definitely an urgent need for finding different methods of treatment for these patients who cannot undergo established modalities of treatment or these have been tried unsuccessfully. Since a large number of these patients will loose their productive life and at the prime of their lives one such alternate therapy, which seems to offer some promise, is “stem cell” therapy, which has been well studied and published in prestigious journals. Current review discuss the safety and therapeutic efficacy of autologous human bone marrow cell (BMC) transplantation and the administration of granulocyte macrophage-colony stimulating factor (GM-CSF).
    VL  - 1
    IS  - 4
    ER  - 

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Author Information
  • Department of Genetics & Stem Cell Research, Narayana Medical College, Nellore, India

  • Narayana Medical Institutions, Nellore, India

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