Symptomatic Disc Herniations: A Review to Understand Pathophysiology and Prediction of Outcomes
Lumbar disc herniation is a common condition with a significant impact on health and economics worldwide. Although deemed unrequired in the majority of cases; surgery has a cardinal role in the management of this disease. Most patients will experience symptomatic improvement following conservative treatment, in fact some will experience complete recovery of their symptoms. Nonetheless the mechanism behind this spontaneous improvement is currently poorly understood, yet it offers the potential to inform therapeutic options that might promote more rapid recovery and prevent the establishment of long-term complications. This review summarises the available literature on the pathophysiological events occurring following lumbar disc herniation, with some relevant reflections on the clinical picture. Also the review highlights the current gaps in our knowledge, and stresses some of the debatable concepts in managing the disease, in order to identify areas where future research might help explain the process of spontaneous recovery from symptomatic lumbar disc herniations and also suggest direction of further research to have a positive impact about outcomes.
Avinash Kumar Kanodia,
Symptomatic Disc Herniations: A Review to Understand Pathophysiology and Prediction of Outcomes, Clinical Neurology and Neuroscience.
Vol. 1, No. 2,
2017, pp. 24-33.
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