Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions

Mohamed Shahat Badawy; Marwa Nasr Eldin Hamed; Ahmed El-Saied Abdel Rahman; Salman Osama Hamdy; Ahmed Yosef Abdel Zaher

doi:doi:10.11648/j.ja.20180601.15

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Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions

Mohamed Shahat Badawy, Marwa Nasr Eldin Hamed, Ahmed El-Saied Abdel Rahman, Salman Osama Hamdy, Ahmed Yosef Abdel Zaher

Published in Journal of Anesthesiology (Volume 6, Issue 1)

Received: 20 April 2018 Accepted: 8 May 2018 Published: 1 July 2018

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Abstract

Background: Surgery is accompanied by postoperative pulmonary functions impairment especially in the prone position. There is evidence suggested that using low tidal volume during general anesthesia may decrease post-operative lung injury. This study aimed to evaluate the effect of low tidal volume on lung functions during mechanical ventilation for general anesthesia while patients lying in the prone position. A prospective clinical trial was performed on 88 patients ASA I&II scheduled for elective surgery while patients lying prone and were randomly assigned to either protective ventilation group A with tidal volume; 5-7 ml/kg, 10 cm H₂O positive end expiratory pressure (PEEP) with recruitment maneuver (RM) or conventional group B with Tidal Volume; 10-12 ml/kg, without both PEEP and RM. The primary efficacy variables were assessed by pulmonary function tests, performed before surgery, and 6, 12 and 24 hours postoperatively. Improvement of lung functions were found in the first post-operative 6 and 12 hours in the low tidal volume group and significant difference was found in all parameters P value 0.001 except PaO₂/FIO₂ ratio P value 0.4. After 24 hours there were significant difference in the FVC, predicted FEV1 and FVC and FEV1/FVC ratio being higher in the low tidal volume group with P value 0.001. Patients in both groups showed similar rates of postoperative chest complications without significant difference. Lung protective ventilation improved lung functions in the first post-operative 24 hours. There was no significant postoperative chest complications difference between the two groups.

Published in	Journal of Anesthesiology (Volume 6, Issue 1)
DOI	10.11648/j.ja.20180601.15
Page(s)	26-32
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Respiratory Functions, Prone Position, Tidal Volume

References

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APA Style

Mohamed Shahat Badawy, Marwa Nasr Eldin Hamed, Ahmed El-Saied Abdel Rahman, Salman Osama Hamdy, Ahmed Yosef Abdel Zaher. (2018). Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions. International Journal of Anesthesia and Clinical Medicine, 6(1), 26-32. https://doi.org/10.11648/j.ja.20180601.15

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ACS Style

Mohamed Shahat Badawy; Marwa Nasr Eldin Hamed; Ahmed El-Saied Abdel Rahman; Salman Osama Hamdy; Ahmed Yosef Abdel Zaher. Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions. Int. J. Anesth. Clin. Med. 2018, 6(1), 26-32. doi: 10.11648/j.ja.20180601.15

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AMA Style

Mohamed Shahat Badawy, Marwa Nasr Eldin Hamed, Ahmed El-Saied Abdel Rahman, Salman Osama Hamdy, Ahmed Yosef Abdel Zaher. Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions. Int J Anesth Clin Med. 2018;6(1):26-32. doi: 10.11648/j.ja.20180601.15

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@article{10.11648/j.ja.20180601.15,
  author = {Mohamed Shahat Badawy and Marwa Nasr Eldin Hamed and Ahmed El-Saied Abdel Rahman and Salman Osama Hamdy and Ahmed Yosef Abdel Zaher},
  title = {Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions},
  journal = {International Journal of Anesthesia and Clinical Medicine},
  volume = {6},
  number = {1},
  pages = {26-32},
  doi = {10.11648/j.ja.20180601.15},
  url = {https://doi.org/10.11648/j.ja.20180601.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ja.20180601.15},
  abstract = {Background: Surgery is accompanied by postoperative pulmonary functions impairment especially in the prone position. There is evidence suggested that using low tidal volume during general anesthesia may decrease post-operative lung injury. This study aimed to evaluate the effect of low tidal volume on lung functions during mechanical ventilation for general anesthesia while patients lying in the prone position. A prospective clinical trial was performed on 88 patients ASA I&II scheduled for elective surgery while patients lying prone and were randomly assigned to either protective ventilation group A with tidal volume; 5-7 ml/kg, 10 cm H2O positive end expiratory pressure (PEEP) with recruitment maneuver (RM) or conventional group B with Tidal Volume; 10-12 ml/kg, without both PEEP and RM. The primary efficacy variables were assessed by pulmonary function tests, performed before surgery, and 6, 12 and 24 hours postoperatively. Improvement of lung functions were found in the first post-operative 6 and 12 hours in the low tidal volume group and significant difference was found in all parameters P value 0.001 except PaO2/FIO2 ratio P value 0.4. After 24 hours there were significant difference in the FVC, predicted FEV1 and FVC and FEV1/FVC ratio being higher in the low tidal volume group with P value 0.001. Patients in both groups showed similar rates of postoperative chest complications without significant difference. Lung protective ventilation improved lung functions in the first post-operative 24 hours. There was no significant postoperative chest complications difference between the two groups.},
 year = {2018}
}

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TY  - JOUR
T1  - Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions
AU  - Mohamed Shahat Badawy
AU  - Marwa Nasr Eldin Hamed
AU  - Ahmed El-Saied Abdel Rahman
AU  - Salman Osama Hamdy
AU  - Ahmed Yosef Abdel Zaher
Y1  - 2018/07/01
PY  - 2018
N1  - https://doi.org/10.11648/j.ja.20180601.15
DO  - 10.11648/j.ja.20180601.15
T2  - International Journal of Anesthesia and Clinical Medicine
JF  - International Journal of Anesthesia and Clinical Medicine
JO  - International Journal of Anesthesia and Clinical Medicine
SP  - 26
EP  - 32
PB  - Science Publishing Group
SN  - 2997-2698
UR  - https://doi.org/10.11648/j.ja.20180601.15
AB  - Background: Surgery is accompanied by postoperative pulmonary functions impairment especially in the prone position. There is evidence suggested that using low tidal volume during general anesthesia may decrease post-operative lung injury. This study aimed to evaluate the effect of low tidal volume on lung functions during mechanical ventilation for general anesthesia while patients lying in the prone position. A prospective clinical trial was performed on 88 patients ASA I&II scheduled for elective surgery while patients lying prone and were randomly assigned to either protective ventilation group A with tidal volume; 5-7 ml/kg, 10 cm H2O positive end expiratory pressure (PEEP) with recruitment maneuver (RM) or conventional group B with Tidal Volume; 10-12 ml/kg, without both PEEP and RM. The primary efficacy variables were assessed by pulmonary function tests, performed before surgery, and 6, 12 and 24 hours postoperatively. Improvement of lung functions were found in the first post-operative 6 and 12 hours in the low tidal volume group and significant difference was found in all parameters P value 0.001 except PaO2/FIO2 ratio P value 0.4. After 24 hours there were significant difference in the FVC, predicted FEV1 and FVC and FEV1/FVC ratio being higher in the low tidal volume group with P value 0.001. Patients in both groups showed similar rates of postoperative chest complications without significant difference. Lung protective ventilation improved lung functions in the first post-operative 24 hours. There was no significant postoperative chest complications difference between the two groups.
VL  - 6
IS  - 1
ER  -

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Author Information

Mohamed Shahat Badawy

Department of chest diseases, Qena faculty of medicine, South Valley University, Qena, Egypt
Marwa Nasr Eldin Hamed

Department of Anesthesiology, Intensive care and Pain Therapy, Qena Faculty of Medicine, South Valley University, Sohag, Egypt
Ahmed El-Saied Abdel Rahman

Department of Anesthesiology, Intensive care and Pain Therapy, Sohag Faculty of Medicine, Sohag University, Qena, Egypt
Salman Osama Hamdy

Department of Anesthesiology, Intensive care and Pain Therapy, Qena Faculty of Medicine, South Valley University, Sohag, Egypt
Ahmed Yosef Abdel Zaher

Department of Anesthesiology, Intensive care and Pain Therapy, Qena Faculty of Medicine, South Valley University, Sohag, Egypt

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APA Style

Mohamed Shahat Badawy, Marwa Nasr Eldin Hamed, Ahmed El-Saied Abdel Rahman, Salman Osama Hamdy, Ahmed Yosef Abdel Zaher. (2018). Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions. International Journal of Anesthesia and Clinical Medicine, 6(1), 26-32. https://doi.org/10.11648/j.ja.20180601.15

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ACS Style

Mohamed Shahat Badawy; Marwa Nasr Eldin Hamed; Ahmed El-Saied Abdel Rahman; Salman Osama Hamdy; Ahmed Yosef Abdel Zaher. Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions. Int. J. Anesth. Clin. Med. 2018, 6(1), 26-32. doi: 10.11648/j.ja.20180601.15

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AMA Style

Mohamed Shahat Badawy, Marwa Nasr Eldin Hamed, Ahmed El-Saied Abdel Rahman, Salman Osama Hamdy, Ahmed Yosef Abdel Zaher. Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions. Int J Anesth Clin Med. 2018;6(1):26-32. doi: 10.11648/j.ja.20180601.15

Copy | Download

@article{10.11648/j.ja.20180601.15,
  author = {Mohamed Shahat Badawy and Marwa Nasr Eldin Hamed and Ahmed El-Saied Abdel Rahman and Salman Osama Hamdy and Ahmed Yosef Abdel Zaher},
  title = {Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions},
  journal = {International Journal of Anesthesia and Clinical Medicine},
  volume = {6},
  number = {1},
  pages = {26-32},
  doi = {10.11648/j.ja.20180601.15},
  url = {https://doi.org/10.11648/j.ja.20180601.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ja.20180601.15},
  abstract = {Background: Surgery is accompanied by postoperative pulmonary functions impairment especially in the prone position. There is evidence suggested that using low tidal volume during general anesthesia may decrease post-operative lung injury. This study aimed to evaluate the effect of low tidal volume on lung functions during mechanical ventilation for general anesthesia while patients lying in the prone position. A prospective clinical trial was performed on 88 patients ASA I&II scheduled for elective surgery while patients lying prone and were randomly assigned to either protective ventilation group A with tidal volume; 5-7 ml/kg, 10 cm H2O positive end expiratory pressure (PEEP) with recruitment maneuver (RM) or conventional group B with Tidal Volume; 10-12 ml/kg, without both PEEP and RM. The primary efficacy variables were assessed by pulmonary function tests, performed before surgery, and 6, 12 and 24 hours postoperatively. Improvement of lung functions were found in the first post-operative 6 and 12 hours in the low tidal volume group and significant difference was found in all parameters P value 0.001 except PaO2/FIO2 ratio P value 0.4. After 24 hours there were significant difference in the FVC, predicted FEV1 and FVC and FEV1/FVC ratio being higher in the low tidal volume group with P value 0.001. Patients in both groups showed similar rates of postoperative chest complications without significant difference. Lung protective ventilation improved lung functions in the first post-operative 24 hours. There was no significant postoperative chest complications difference between the two groups.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Evaluation of Low Tidal Volume During General Anesthesia in Prone Position on Respiratory Functions
AU  - Mohamed Shahat Badawy
AU  - Marwa Nasr Eldin Hamed
AU  - Ahmed El-Saied Abdel Rahman
AU  - Salman Osama Hamdy
AU  - Ahmed Yosef Abdel Zaher
Y1  - 2018/07/01
PY  - 2018
N1  - https://doi.org/10.11648/j.ja.20180601.15
DO  - 10.11648/j.ja.20180601.15
T2  - International Journal of Anesthesia and Clinical Medicine
JF  - International Journal of Anesthesia and Clinical Medicine
JO  - International Journal of Anesthesia and Clinical Medicine
SP  - 26
EP  - 32
PB  - Science Publishing Group
SN  - 2997-2698
UR  - https://doi.org/10.11648/j.ja.20180601.15
AB  - Background: Surgery is accompanied by postoperative pulmonary functions impairment especially in the prone position. There is evidence suggested that using low tidal volume during general anesthesia may decrease post-operative lung injury. This study aimed to evaluate the effect of low tidal volume on lung functions during mechanical ventilation for general anesthesia while patients lying in the prone position. A prospective clinical trial was performed on 88 patients ASA I&II scheduled for elective surgery while patients lying prone and were randomly assigned to either protective ventilation group A with tidal volume; 5-7 ml/kg, 10 cm H2O positive end expiratory pressure (PEEP) with recruitment maneuver (RM) or conventional group B with Tidal Volume; 10-12 ml/kg, without both PEEP and RM. The primary efficacy variables were assessed by pulmonary function tests, performed before surgery, and 6, 12 and 24 hours postoperatively. Improvement of lung functions were found in the first post-operative 6 and 12 hours in the low tidal volume group and significant difference was found in all parameters P value 0.001 except PaO2/FIO2 ratio P value 0.4. After 24 hours there were significant difference in the FVC, predicted FEV1 and FVC and FEV1/FVC ratio being higher in the low tidal volume group with P value 0.001. Patients in both groups showed similar rates of postoperative chest complications without significant difference. Lung protective ventilation improved lung functions in the first post-operative 24 hours. There was no significant postoperative chest complications difference between the two groups.
VL  - 6
IS  - 1
ER  -

Copy | Download