Study aim: To characterize the associated factors of postoperative renal global functional deterioration after partial nephrectomy (PN), comprehensive analyses were performed using multiple factors categorized as data from pre, intra and postoperative periods. Methods: Ninety-three patients underwent PN. Estimated glomerular filtration rate (eGFR) and computed tomography (CT) scans were examined pre- and 6 months postoperatively. Renal global functional deterioration after PN was assessed by postoperative percent of eGFR decline. Pre- and postoperative renal parenchymal volume (RPV) was measured by the Synapse Vincent volumetric analyzer which creates a reconstructed image from a CT scan. Additional factors that were analyzed included patient demographics, comorbidities, surgical factors and tumor pathology. All factors demonstrating statistical tendencies (P < 0.1) in univariate analyses were subjected to multivariate logistic regression analysis. Two groups were categorized according to the degree of eGFR decline. Groups A and B were categorized as less than 15% and greater than 15% declines, respectively. Results: The case distributions of hypertension (HTN) and male gender were significantly shifted in group B. Significant compensatory renal hypertrophy of the contralateral side occurred postoperatively. The percent increment of RPV in the contralateral side in group B was significantly lower than that in group A. In multivariate analysis, HTN was the sole independent associated factor in group B. Conclusions: Host factors, rather than surgical factors, may be associated with postoperative renal global functional deterioration in PN. Surgeons should consider medical problems in addition to surgical skills especially in HTN patients.
| Published in | Advances in Surgical Sciences (Volume 7, Issue 1) |
| DOI | 10.11648/j.ass.20190701.15 |
| Page(s) | 21-28 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Estimated Glomerular Filtration Rate, Partial Nephrectomy, Renal Function, Renal Volume
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APA Style
Takehiro Sejima, Toshihiko Masago, Tetsuya Yumioka, Shuichi Morizane, Masashi Honda, et al. (2019). Comprehensive Analyses of Factors Associated with Postoperative Renal Global Function in Patients Treated by Partial Nephrectomy. Advances in Surgical Sciences, 7(1), 21-28. https://doi.org/10.11648/j.ass.20190701.15
ACS Style
Takehiro Sejima; Toshihiko Masago; Tetsuya Yumioka; Shuichi Morizane; Masashi Honda, et al. Comprehensive Analyses of Factors Associated with Postoperative Renal Global Function in Patients Treated by Partial Nephrectomy. Adv. Surg. Sci. 2019, 7(1), 21-28. doi: 10.11648/j.ass.20190701.15
AMA Style
Takehiro Sejima, Toshihiko Masago, Tetsuya Yumioka, Shuichi Morizane, Masashi Honda, et al. Comprehensive Analyses of Factors Associated with Postoperative Renal Global Function in Patients Treated by Partial Nephrectomy. Adv Surg Sci. 2019;7(1):21-28. doi: 10.11648/j.ass.20190701.15
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Download@article{10.11648/j.ass.20190701.15,
author = {Takehiro Sejima and Toshihiko Masago and Tetsuya Yumioka and Shuichi Morizane and Masashi Honda and Atsushi Takenaka},
title = {Comprehensive Analyses of Factors Associated with Postoperative Renal Global Function in Patients Treated by Partial Nephrectomy},
journal = {Advances in Surgical Sciences},
volume = {7},
number = {1},
pages = {21-28},
doi = {10.11648/j.ass.20190701.15},
url = {https://doi.org/10.11648/j.ass.20190701.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ass.20190701.15},
abstract = {Study aim: To characterize the associated factors of postoperative renal global functional deterioration after partial nephrectomy (PN), comprehensive analyses were performed using multiple factors categorized as data from pre, intra and postoperative periods. Methods: Ninety-three patients underwent PN. Estimated glomerular filtration rate (eGFR) and computed tomography (CT) scans were examined pre- and 6 months postoperatively. Renal global functional deterioration after PN was assessed by postoperative percent of eGFR decline. Pre- and postoperative renal parenchymal volume (RPV) was measured by the Synapse Vincent volumetric analyzer which creates a reconstructed image from a CT scan. Additional factors that were analyzed included patient demographics, comorbidities, surgical factors and tumor pathology. All factors demonstrating statistical tendencies (P Results: The case distributions of hypertension (HTN) and male gender were significantly shifted in group B. Significant compensatory renal hypertrophy of the contralateral side occurred postoperatively. The percent increment of RPV in the contralateral side in group B was significantly lower than that in group A. In multivariate analysis, HTN was the sole independent associated factor in group B. Conclusions: Host factors, rather than surgical factors, may be associated with postoperative renal global functional deterioration in PN. Surgeons should consider medical problems in addition to surgical skills especially in HTN patients.},
year = {2019}
}
TY - JOUR T1 - Comprehensive Analyses of Factors Associated with Postoperative Renal Global Function in Patients Treated by Partial Nephrectomy AU - Takehiro Sejima AU - Toshihiko Masago AU - Tetsuya Yumioka AU - Shuichi Morizane AU - Masashi Honda AU - Atsushi Takenaka Y1 - 2019/04/08 PY - 2019 N1 - https://doi.org/10.11648/j.ass.20190701.15 DO - 10.11648/j.ass.20190701.15 T2 - Advances in Surgical Sciences JF - Advances in Surgical Sciences JO - Advances in Surgical Sciences SP - 21 EP - 28 PB - Science Publishing Group SN - 2376-6182 UR - https://doi.org/10.11648/j.ass.20190701.15 AB - Study aim: To characterize the associated factors of postoperative renal global functional deterioration after partial nephrectomy (PN), comprehensive analyses were performed using multiple factors categorized as data from pre, intra and postoperative periods. Methods: Ninety-three patients underwent PN. Estimated glomerular filtration rate (eGFR) and computed tomography (CT) scans were examined pre- and 6 months postoperatively. Renal global functional deterioration after PN was assessed by postoperative percent of eGFR decline. Pre- and postoperative renal parenchymal volume (RPV) was measured by the Synapse Vincent volumetric analyzer which creates a reconstructed image from a CT scan. Additional factors that were analyzed included patient demographics, comorbidities, surgical factors and tumor pathology. All factors demonstrating statistical tendencies (P Results: The case distributions of hypertension (HTN) and male gender were significantly shifted in group B. Significant compensatory renal hypertrophy of the contralateral side occurred postoperatively. The percent increment of RPV in the contralateral side in group B was significantly lower than that in group A. In multivariate analysis, HTN was the sole independent associated factor in group B. Conclusions: Host factors, rather than surgical factors, may be associated with postoperative renal global functional deterioration in PN. Surgeons should consider medical problems in addition to surgical skills especially in HTN patients. VL - 7 IS - 1 ER -
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