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Platelet-Rich Plasma (PRP) Treatment in Vaginal Penetration Disorders

Received: 9 May 2020    Accepted: 25 May 2020    Published: 4 June 2020
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Abstract

Vaginal Penetration Disorders (VPD) consist a major sexual disorder that has a significant impression on young ladies and couple’s relationships and also consist of a predisposing factor for anxiety disorders. All existing treatments of vaginismus are still a big challenge and often without success. Before performing PRP patients were referred to the gynaecologist, urologist or psychologist. Almost in every case after several attempts to be treated, they were disappointed with the results. Often, they have admitted to accept their problem and keep suffering because no physician could offer any effective help with significant results. We are reporting in this article a serie of ten cases where the Platelet Rich Plasma (PRP) treatment was tried based on their voluntary participation due to particular and relative sexual problems. Based on the results that are exposed here, we can say that PRP clearly has a positive effect not only on rejuvenation of the female genital structurebut also on improving VPD symptoms. It reduces pain, reduces mucosal dryness and chronic fissuration. The duration of the effect on the vaginal structure as well as clinical improvements requires more case studying and research. These patients will be evaluated for the coming 2 years to acquire more data to be analyzed in order to complete our observational study. It is nothing but the beginning of a new era in the sexual dysfunction therapy.

Published in Journal of Gynecology and Obstetrics (Volume 8, Issue 4)
DOI 10.11648/j.jgo.20200804.11
Page(s) 71-80
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Vaginal Penetration Disorders, Sexual Disorder, Vaginismus, Platelet-rich Treatment

References
[1] The diagnostic and Statistical Manual of Mental Disorders, 5th ed.; DSM-5; American Psychiatric Association, 2013
[2] Melnik T, Oswaldo M. Vaginismus is ruining sex. Research must move beyond penetration. Jnr for evidently Cochrane, 2017.
[3] Van der Velde J, A Psychophysiological Investigation of the Pelvic Floor. The Mechanism of Vaginism, Thesis university Amsterdam, 1999.
[4] Konstantinos H, Hatzichristou D Sexual Dysfunctions: Classifications and Definitions; J Sex Med, 2007 Jan; 4 (1): 241-250.
[5] Ulrich S., Schnyder-Lüthi C., Ballinari P., Blaser A. Therapy for Vaginismus: In Vivo Versus In Vitro Desensitization. Can J Psychiatry. 1998 Nov; 43 (9): 941-4.
[6] Elghblawi E. Platelet-rich plasma, the ultimate secret for youthful skin elixir and hair growth triggering. J Cosmet Dermatol. 2018 Jun; 17 (3): 423-430.
[7] Seok H., Eun S., Tae H. Rejuvenation Using Platelet-rich Plasma and Lipofilling for Vaginal Atrophy and Lichen Sclerosis.Journal of Menopausal Medicine 2017; 23: 63-68
[8] Yuvika R., Sujata M., Mahesh V. et al. Platelet-rich fibrin: the benefits. British Journal of Oral and Maxillofacial Surgery 54 (2016) 57–61
[9] Shu-Hung H., Sheng-Hua W., Su-Shin L., et al. Platelet-Rich Plasma Injection in Burn Scar Areas Int J Med Sci. 2018; 15 (3): 238–247.
[10] Alleviates Neuropathic Scar Pain. International Journal of Medical Sciences2018; 15 (3): 238-247.
[11] Xiaolin H., Yan Ze., Rongrong Z., et al. Using platelet-rich plasma for the treatment of symptomatic cervical ectopy. International Journal of Gynecology and Obstetrics 119 (2012) 26–29.
[12] Osaid H. A., Ioannis G. The evidence behind the use of platelet-rich plasma (PRP) in scar management: Scars, Burns & Healing Volume 4: 1–15. 2018.
[13] Yajie C., Jingjie L., Yuqing C., et. Al. Autologous platelet-rich plasma promotes endometrial growth and improves pregnancy outcome during in vitro fertilization. International Journal of Molecular Sciences. 2015; 8 (1): 1286-1290.
[14] Franka K., Tanja S., Melanie U., et al. Comparative Analysis of Different Platelet Lysates and Platelet Rich Preparations to Stimulate Tendon Cell Biology. Int J Mol Sci. 2018 Jan 10; 19 (1). pii: E212.
[15] John W. Platelet-rich therapies for musculoskeletal soft tissue injuries. Cochrane Database Syst Rev. 2013 Dec 23; (12): CD010071.
[16] Tasmania del P., María M. T., Isabel A., et al. Platelet-rich plasma for the treatment of diabetic foot ulcers. Wound Repair Regen 2019 Mar; 27 (2): 170-182.
Cite This Article
  • APA Style

    El Haddad Cynthia, Darido Jessie, Gharjestani Shamsia, Diari Jed. (2020). Platelet-Rich Plasma (PRP) Treatment in Vaginal Penetration Disorders. Journal of Gynecology and Obstetrics, 8(4), 71-80. https://doi.org/10.11648/j.jgo.20200804.11

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    ACS Style

    El Haddad Cynthia; Darido Jessie; Gharjestani Shamsia; Diari Jed. Platelet-Rich Plasma (PRP) Treatment in Vaginal Penetration Disorders. J. Gynecol. Obstet. 2020, 8(4), 71-80. doi: 10.11648/j.jgo.20200804.11

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    AMA Style

    El Haddad Cynthia, Darido Jessie, Gharjestani Shamsia, Diari Jed. Platelet-Rich Plasma (PRP) Treatment in Vaginal Penetration Disorders. J Gynecol Obstet. 2020;8(4):71-80. doi: 10.11648/j.jgo.20200804.11

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  • @article{10.11648/j.jgo.20200804.11,
      author = {El Haddad Cynthia and Darido Jessie and Gharjestani Shamsia and Diari Jed},
      title = {Platelet-Rich Plasma (PRP) Treatment in Vaginal Penetration Disorders},
      journal = {Journal of Gynecology and Obstetrics},
      volume = {8},
      number = {4},
      pages = {71-80},
      doi = {10.11648/j.jgo.20200804.11},
      url = {https://doi.org/10.11648/j.jgo.20200804.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20200804.11},
      abstract = {Vaginal Penetration Disorders (VPD) consist a major sexual disorder that has a significant impression on young ladies and couple’s relationships and also consist of a predisposing factor for anxiety disorders. All existing treatments of vaginismus are still a big challenge and often without success. Before performing PRP patients were referred to the gynaecologist, urologist or psychologist. Almost in every case after several attempts to be treated, they were disappointed with the results. Often, they have admitted to accept their problem and keep suffering because no physician could offer any effective help with significant results. We are reporting in this article a serie of ten cases where the Platelet Rich Plasma (PRP) treatment was tried based on their voluntary participation due to particular and relative sexual problems. Based on the results that are exposed here, we can say that PRP clearly has a positive effect not only on rejuvenation of the female genital structurebut also on improving VPD symptoms. It reduces pain, reduces mucosal dryness and chronic fissuration. The duration of the effect on the vaginal structure as well as clinical improvements requires more case studying and research. These patients will be evaluated for the coming 2 years to acquire more data to be analyzed in order to complete our observational study. It is nothing but the beginning of a new era in the sexual dysfunction therapy.},
     year = {2020}
    }
    

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    AB  - Vaginal Penetration Disorders (VPD) consist a major sexual disorder that has a significant impression on young ladies and couple’s relationships and also consist of a predisposing factor for anxiety disorders. All existing treatments of vaginismus are still a big challenge and often without success. Before performing PRP patients were referred to the gynaecologist, urologist or psychologist. Almost in every case after several attempts to be treated, they were disappointed with the results. Often, they have admitted to accept their problem and keep suffering because no physician could offer any effective help with significant results. We are reporting in this article a serie of ten cases where the Platelet Rich Plasma (PRP) treatment was tried based on their voluntary participation due to particular and relative sexual problems. Based on the results that are exposed here, we can say that PRP clearly has a positive effect not only on rejuvenation of the female genital structurebut also on improving VPD symptoms. It reduces pain, reduces mucosal dryness and chronic fissuration. The duration of the effect on the vaginal structure as well as clinical improvements requires more case studying and research. These patients will be evaluated for the coming 2 years to acquire more data to be analyzed in order to complete our observational study. It is nothing but the beginning of a new era in the sexual dysfunction therapy.
    VL  - 8
    IS  - 4
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Author Information
  • Department of Obstetrics and Gynecology, Faculty of Medicine, Holy Spirit University of Kaslik, Jounieh, Lebanon; Department of Obstetrics and Gynecology, The Centre Hospitalier Universitaire Notre Dame de Secours, Byblos, Lebanon; Department of Obstetrics and Gynecology, Centre Hospitalier du Sud Francilien, Corbeil Essonnes, France

  • Department of Obstetrics and Gynecology, Faculty of Medical Sciences, The Lebanese University, Beirut, Lebanon; Department of Obstetrics and Gynecology, Centre Hospitalier du Sud Francilien, Corbeil Essonnes, France

  • Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium

  • Department of Obstetrics and Gynecology, Centre Hospitalier du Sud Francilien, Corbeil Essonnes, France

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