Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study

Wei Li; Qiong Dai; Yongying Qiu; Jianqiong Liu; Yan Guo; Bin Wang

doi:doi:10.11648/j.jgo.20190705.16

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Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study

Wei Li, Qiong Dai, Yongying Qiu, Jianqiong Liu, Yan Guo, Bin Wang

Published in Journal of Gynecology and Obstetrics (Volume 7, Issue 5)

Received: 8 September 2019 Accepted: 25 September 2019 Published: 10 October 2019

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Abstract

Background The requirement of vitamin D in different stage may be diverse, but research on the variation trend of vitamin D status during infancy is scarce. Objective This study aimed to explore the variation trend of vitamin D status and influencing factors of vitamin D deficiency and insufficiency during wintertime among infants. Methods A cross-sectional study was conducted. A total of 500 infants were included in our study during January to March 2017. The serum 25(OH)D was performed by chemiluminescent assay. Multivariate Logistic regression was conducted to evaluate the influencing factors of vitamin D deficiency and vitamin D insufficiency. Results The older infants had a higher concentration of vitamin D than younger infants (r=0.62, P<0.0001). And the overall prevalence of vitamin D deficiency and insufficiency were 33.80% and 18.00%, respectively. With the increase of month age, the risk of vitamin D deficiency (OR=0.63, 95%CI: 0.57-0.70) and insufficiency (OR=0.69, 95%CI: 0.62-0.77) were both declined. In addition, the infant with low birthweight, breastfed, living in rural area were correlated with a higher risk of vitamin D deficiency and insufficiency (P<0.05). Conclusion Vitamin D deficiency and insufficiency prevalence changed with month age, routine monitoring of vitamin D levels is necessary for infant.

Published in	Journal of Gynecology and Obstetrics (Volume 7, Issue 5)
DOI	10.11648/j.jgo.20190705.16
Page(s)	149-154
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Vitamin D Status, Vitamin D Deficiency, Vitamin D Supplementation, Infant, Wintertime, Breastfed

References

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APA Style

Wei Li, Qiong Dai, Yongying Qiu, Jianqiong Liu, Yan Guo, et al. (2019). Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study. Journal of Gynecology and Obstetrics, 7(5), 149-154. https://doi.org/10.11648/j.jgo.20190705.16

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ACS Style

Wei Li; Qiong Dai; Yongying Qiu; Jianqiong Liu; Yan Guo, et al. Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study. J. Gynecol. Obstet. 2019, 7(5), 149-154. doi: 10.11648/j.jgo.20190705.16

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AMA Style

Wei Li, Qiong Dai, Yongying Qiu, Jianqiong Liu, Yan Guo, et al. Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study. J Gynecol Obstet. 2019;7(5):149-154. doi: 10.11648/j.jgo.20190705.16

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@article{10.11648/j.jgo.20190705.16,
  author = {Wei Li and Qiong Dai and Yongying Qiu and Jianqiong Liu and Yan Guo and Bin Wang},
  title = {Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {7},
  number = {5},
  pages = {149-154},
  doi = {10.11648/j.jgo.20190705.16},
  url = {https://doi.org/10.11648/j.jgo.20190705.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20190705.16},
  abstract = {Background The requirement of vitamin D in different stage may be diverse, but research on the variation trend of vitamin D status during infancy is scarce. Objective This study aimed to explore the variation trend of vitamin D status and influencing factors of vitamin D deficiency and insufficiency during wintertime among infants. Methods A cross-sectional study was conducted. A total of 500 infants were included in our study during January to March 2017. The serum 25(OH)D was performed by chemiluminescent assay. Multivariate Logistic regression was conducted to evaluate the influencing factors of vitamin D deficiency and vitamin D insufficiency. Results The older infants had a higher concentration of vitamin D than younger infants (r=0.62, P<0.0001). And the overall prevalence of vitamin D deficiency and insufficiency were 33.80% and 18.00%, respectively. With the increase of month age, the risk of vitamin D deficiency (OR=0.63, 95%CI: 0.57-0.70) and insufficiency (OR=0.69, 95%CI: 0.62-0.77) were both declined. In addition, the infant with low birthweight, breastfed, living in rural area were correlated with a higher risk of vitamin D deficiency and insufficiency (P<0.05). Conclusion Vitamin D deficiency and insufficiency prevalence changed with month age, routine monitoring of vitamin D levels is necessary for infant.},
 year = {2019}
}

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TY - JOUR
T1 - Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study
AU - Wei Li
AU - Qiong Dai
AU - Yongying Qiu
AU - Jianqiong Liu
AU - Yan Guo
AU - Bin Wang
Y1 - 2019/10/10
PY - 2019
N1 - https://doi.org/10.11648/j.jgo.20190705.16
DO - 10.11648/j.jgo.20190705.16
T2 - Journal of Gynecology and Obstetrics
JF - Journal of Gynecology and Obstetrics
JO - Journal of Gynecology and Obstetrics
SP - 149
EP - 154
PB - Science Publishing Group
SN - 2376-7820
UR - https://doi.org/10.11648/j.jgo.20190705.16
AB - Background The requirement of vitamin D in different stage may be diverse, but research on the variation trend of vitamin D status during infancy is scarce. Objective This study aimed to explore the variation trend of vitamin D status and influencing factors of vitamin D deficiency and insufficiency during wintertime among infants. Methods A cross-sectional study was conducted. A total of 500 infants were included in our study during January to March 2017. The serum 25(OH)D was performed by chemiluminescent assay. Multivariate Logistic regression was conducted to evaluate the influencing factors of vitamin D deficiency and vitamin D insufficiency. Results The older infants had a higher concentration of vitamin D than younger infants (r=0.62, P<0.0001). And the overall prevalence of vitamin D deficiency and insufficiency were 33.80% and 18.00%, respectively. With the increase of month age, the risk of vitamin D deficiency (OR=0.63, 95%CI: 0.57-0.70) and insufficiency (OR=0.69, 95%CI: 0.62-0.77) were both declined. In addition, the infant with low birthweight, breastfed, living in rural area were correlated with a higher risk of vitamin D deficiency and insufficiency (P<0.05). Conclusion Vitamin D deficiency and insufficiency prevalence changed with month age, routine monitoring of vitamin D levels is necessary for infant.
VL - 7
IS - 5
ER -

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Author Information

Wei Li

Department of Pharmacy, Maternal and Child Health Hospital of Hubei Province, Wuhan, China; Women and Children’s Hospital of Hubei Province, Wuhan, China
Qiong Dai

Women and Children’s Hospital of Hubei Province, Wuhan, China; Health Care Department, Maternal and Child Health Hospital of Hubei Province, Wuhan, China
Yongying Qiu

Department of Gynaecology, Maternal and Child health Hospital of Xinfen County, Ganzhou, China
Jianqiong Liu

Women and Children’s Hospital of Hubei Province, Wuhan, China; Department of Child Health Care, Maternal and Child Health Hospital of Hubei Province, Wuhan, China
Yan Guo

Wuhan Centers for Disease Prevention and Control, Wuhan, China
Bin Wang

Department of Laboratory of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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APA Style

Wei Li, Qiong Dai, Yongying Qiu, Jianqiong Liu, Yan Guo, et al. (2019). Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study. Journal of Gynecology and Obstetrics, 7(5), 149-154. https://doi.org/10.11648/j.jgo.20190705.16

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ACS Style

Wei Li; Qiong Dai; Yongying Qiu; Jianqiong Liu; Yan Guo, et al. Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study. J. Gynecol. Obstet. 2019, 7(5), 149-154. doi: 10.11648/j.jgo.20190705.16

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AMA Style

Wei Li, Qiong Dai, Yongying Qiu, Jianqiong Liu, Yan Guo, et al. Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study. J Gynecol Obstet. 2019;7(5):149-154. doi: 10.11648/j.jgo.20190705.16

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@article{10.11648/j.jgo.20190705.16,
  author = {Wei Li and Qiong Dai and Yongying Qiu and Jianqiong Liu and Yan Guo and Bin Wang},
  title = {Variation Trend of Vitamin D Status in Wintertime Among Infants: A Cross-sectional Study},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {7},
  number = {5},
  pages = {149-154},
  doi = {10.11648/j.jgo.20190705.16},
  url = {https://doi.org/10.11648/j.jgo.20190705.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20190705.16},
  abstract = {Background The requirement of vitamin D in different stage may be diverse, but research on the variation trend of vitamin D status during infancy is scarce. Objective This study aimed to explore the variation trend of vitamin D status and influencing factors of vitamin D deficiency and insufficiency during wintertime among infants. Methods A cross-sectional study was conducted. A total of 500 infants were included in our study during January to March 2017. The serum 25(OH)D was performed by chemiluminescent assay. Multivariate Logistic regression was conducted to evaluate the influencing factors of vitamin D deficiency and vitamin D insufficiency. Results The older infants had a higher concentration of vitamin D than younger infants (r=0.62, P<0.0001). And the overall prevalence of vitamin D deficiency and insufficiency were 33.80% and 18.00%, respectively. With the increase of month age, the risk of vitamin D deficiency (OR=0.63, 95%CI: 0.57-0.70) and insufficiency (OR=0.69, 95%CI: 0.62-0.77) were both declined. In addition, the infant with low birthweight, breastfed, living in rural area were correlated with a higher risk of vitamin D deficiency and insufficiency (P<0.05). Conclusion Vitamin D deficiency and insufficiency prevalence changed with month age, routine monitoring of vitamin D levels is necessary for infant.},
 year = {2019}
}

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