This case report, it’s about a patient I met during prenatal consultation, she was in the 2nd semester of her pregnancy, exactly at 25 weeks. During the physical examination, we found, she had a hypoplasia of minor labia, an incomplete vaginal diaphragm with a vaginal cup, and a hypertrophy of clitoris. We decide to make some biological and instrumental examinations. After getting the result, we concluded she has a pseudo hermaphroditism associated with malformation of 1/3 of vagina. Reason why the way of the delivery choose was a C-section. Female pseudo hermaphroditism is the most frequent (FPH) sexual ambiguity. It is characterized by the extension of abnormality of the sexual differentiation during the fetal life in the female fetus by a maternal or fetal hyper-genesis. The authors propose through a clinical case with a patient 46XX DSD pregnant. The main cause of this pathology is congenital adrenal hyperplasia, which we lead to deficits of 21-hydoxylase, 11-beta-hydroxylase, 3-beta-hydroxysteroid dehydrogenase, but 95% of the congenital adrenal hyperplasia is the deficiency of 21-hydoxylase. The treatment of congenital adrenal hyperplasia depend of the cause, hormone replacement therapy like (dexamethasone, hydrocortisone), most often the treatment for life is needed. From this we propose to make review of literature focusing on it.
| Published in | Journal of Gynecology and Obstetrics (Volume 7, Issue 5) |
| DOI | 10.11648/j.jgo.20190705.14 |
| Page(s) | 142-144 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
46 XX DSD, Karyotype, Pregnancy, Congenital Adrenal Hyperplasia
| [1] | N. El amrani, m. Outifa, s. Nabil, i. Chemry, s. El hajoui, mt. Alaoui. A propos d’un cas de pseudo-hermaphrodisme féminin, med du maghreb 2000 n 80. |
| [2] | Mm niang, l. Niang, w. Kalai, sm gueye, ct cisse le pseudo-hermaphrodisme féminin, med d’afrique noire juin 2015, vol 62. N 5. |
| [3] | C. Pienkowski – a. Cartault anomalie du développement sexuel du nouveau-né—diu maternité Novembre 2008. |
| [4] | Le maillon faible l’abs des syndromes 1990, page 438-448. |
| [5] | D. Ndour, p.m. faye, a.sagna, d. Gueye, a.s. signate 46 xx male or ovotesticular dsd sry negative. |
| [6] | Francois. R. Ambiguïté sexuelle; rev. Fr. Gynécol. Obstet. 1986, 81, 445-450. |
| [7] | Kuttenn f., perby s., lebouc y. Anomalie de la différenciation sexuelle. Méd. Reprod. Mauvais jarvis p. - gynécologie endocrinienne, r. Situk ware, 2e ed, paris, 1988-pp 282–213. |
| [8] | Adriana chedel, elodie fatio, sarah kiehl, audrey perseghini, variations du developpement sexuel, travail de mobilité en partenariat avec la faculté de médecine tuteur: philippe garnerin juin 2013. |
| [9] | Dr saim sid ahmed, dr haffaf anis, «malformations genitales chez les nouveaux-nes», encadré par: dr blidi, année universitaire: 2013-2014. |
| [10] | Deficit en aromatase placentaire et pseudohermaphrodisme feminin, medecine/sciences 1994; jo: 342-3. |
| [11] | Muhammad tahir m bhinder, amin saleh halum and sandy lee, pseudohermaphroditism: a multi-faceted pathosis, nova southeastern university, palm beach gardens, Florida, USA. |
| [12] | Hugh jolly, female pseudohermaphroditism: a description of two unusual cases., proc r soc med. 1959 apr; 52 (4): 300–301. |
| [13] | Perloff wh, conger kb, ley l. Female pseudohermaphroditism: a description of two unusual cases. J clin endocrinol. 1953; 13: 783–790. [pub med]. |
| [14] | Guide médecin – pnds «hyperplasie congénitale des surrénales». |
| [15] | Pr juliane leger, hyperplasie congénitale des surrénales par déficit en 21-hydroxylase classique, octobre 2012. |
| [16] | G masson, paris, 1998 annales d'endocrinologie (paris) 1998, 59, 311-31. |
APA Style
Taliana Stephie Gondjout, Omar Gassama, Soukaina El Alaoui, Helene Chami, Abdoul Aziz Diouf, et al. (2019). Female Hermaphroditism and Term Pregnancy: About a Case at the National Hospital of Pikine and Review of Literature. Journal of Gynecology and Obstetrics, 7(5), 142-144. https://doi.org/10.11648/j.jgo.20190705.14
ACS Style
Taliana Stephie Gondjout; Omar Gassama; Soukaina El Alaoui; Helene Chami; Abdoul Aziz Diouf, et al. Female Hermaphroditism and Term Pregnancy: About a Case at the National Hospital of Pikine and Review of Literature. J. Gynecol. Obstet. 2019, 7(5), 142-144. doi: 10.11648/j.jgo.20190705.14
AMA Style
Taliana Stephie Gondjout, Omar Gassama, Soukaina El Alaoui, Helene Chami, Abdoul Aziz Diouf, et al. Female Hermaphroditism and Term Pregnancy: About a Case at the National Hospital of Pikine and Review of Literature. J Gynecol Obstet. 2019;7(5):142-144. doi: 10.11648/j.jgo.20190705.14
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.jgo.20190705.14,
author = {Taliana Stephie Gondjout and Omar Gassama and Soukaina El Alaoui and Helene Chami and Abdoul Aziz Diouf and Alassane Diouf},
title = {Female Hermaphroditism and Term Pregnancy: About a Case at the National Hospital of Pikine and Review of Literature},
journal = {Journal of Gynecology and Obstetrics},
volume = {7},
number = {5},
pages = {142-144},
doi = {10.11648/j.jgo.20190705.14},
url = {https://doi.org/10.11648/j.jgo.20190705.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20190705.14},
abstract = {This case report, it’s about a patient I met during prenatal consultation, she was in the 2nd semester of her pregnancy, exactly at 25 weeks. During the physical examination, we found, she had a hypoplasia of minor labia, an incomplete vaginal diaphragm with a vaginal cup, and a hypertrophy of clitoris. We decide to make some biological and instrumental examinations. After getting the result, we concluded she has a pseudo hermaphroditism associated with malformation of 1/3 of vagina. Reason why the way of the delivery choose was a C-section. Female pseudo hermaphroditism is the most frequent (FPH) sexual ambiguity. It is characterized by the extension of abnormality of the sexual differentiation during the fetal life in the female fetus by a maternal or fetal hyper-genesis. The authors propose through a clinical case with a patient 46XX DSD pregnant. The main cause of this pathology is congenital adrenal hyperplasia, which we lead to deficits of 21-hydoxylase, 11-beta-hydroxylase, 3-beta-hydroxysteroid dehydrogenase, but 95% of the congenital adrenal hyperplasia is the deficiency of 21-hydoxylase. The treatment of congenital adrenal hyperplasia depend of the cause, hormone replacement therapy like (dexamethasone, hydrocortisone), most often the treatment for life is needed. From this we propose to make review of literature focusing on it.},
year = {2019}
}
TY - JOUR T1 - Female Hermaphroditism and Term Pregnancy: About a Case at the National Hospital of Pikine and Review of Literature AU - Taliana Stephie Gondjout AU - Omar Gassama AU - Soukaina El Alaoui AU - Helene Chami AU - Abdoul Aziz Diouf AU - Alassane Diouf Y1 - 2019/10/09 PY - 2019 N1 - https://doi.org/10.11648/j.jgo.20190705.14 DO - 10.11648/j.jgo.20190705.14 T2 - Journal of Gynecology and Obstetrics JF - Journal of Gynecology and Obstetrics JO - Journal of Gynecology and Obstetrics SP - 142 EP - 144 PB - Science Publishing Group SN - 2376-7820 UR - https://doi.org/10.11648/j.jgo.20190705.14 AB - This case report, it’s about a patient I met during prenatal consultation, she was in the 2nd semester of her pregnancy, exactly at 25 weeks. During the physical examination, we found, she had a hypoplasia of minor labia, an incomplete vaginal diaphragm with a vaginal cup, and a hypertrophy of clitoris. We decide to make some biological and instrumental examinations. After getting the result, we concluded she has a pseudo hermaphroditism associated with malformation of 1/3 of vagina. Reason why the way of the delivery choose was a C-section. Female pseudo hermaphroditism is the most frequent (FPH) sexual ambiguity. It is characterized by the extension of abnormality of the sexual differentiation during the fetal life in the female fetus by a maternal or fetal hyper-genesis. The authors propose through a clinical case with a patient 46XX DSD pregnant. The main cause of this pathology is congenital adrenal hyperplasia, which we lead to deficits of 21-hydoxylase, 11-beta-hydroxylase, 3-beta-hydroxysteroid dehydrogenase, but 95% of the congenital adrenal hyperplasia is the deficiency of 21-hydoxylase. The treatment of congenital adrenal hyperplasia depend of the cause, hormone replacement therapy like (dexamethasone, hydrocortisone), most often the treatment for life is needed. From this we propose to make review of literature focusing on it. VL - 7 IS - 5 ER -
Information
Email: