The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain
American Journal of Clinical and Experimental Medicine
Volume 8, Issue 1, January 2020, Pages: 1-5
Received: Jan. 31, 2020;
Accepted: Feb. 18, 2020;
Published: Feb. 26, 2020
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Zhenhua Huang, Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China
Qianlin Gu, Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China
Hong Zhan, Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China
Zhen Yang, Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China
Yuee Chen, Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China
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To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (P<0.05). The predictive ROC curve area of GRACE scores in 30-day MACE was 0.739 (0.687 to 0.791). The probability of 30-day cardiovascular adverse events in various GRACE score risk stratification was 2.0% (low-risk), 5.33% (medium-risk), and 9.67% (high-risk), respectively. The GRACE score was a useful predictor to the occurrence of 30-day cardiovascular adverse events in acute chest pain patients. Patients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.
GRACE Scores, Acute Chest Pain, Risk Stratification, Cardiovascular Adverse Events
To cite this article
The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain, American Journal of Clinical and Experimental Medicine.
Vol. 8, No. 1,
2020, pp. 1-5.
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
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