Sri Lanka has been recognized as one of the fastest aging populations from the developing countries. There is a large senior population in the country. Since age is the biggest risk factor for Dementia, the need to create awareness and management is an increasing necessity. Sarasvatha Choorna is one of the polyherbal preparation used in Ayurveda for the management of Dementia which consists of 12 medicinal plants. In the present study, an attempt was made to standardize Sarasvatha Choorna by using standard protocols. Standardization was carried out by determination of total ash, water soluble ash, acid insoluble ash, microbial counts, heavy metals, phytochemical screening and development of TLC-densitogram fingerprints. Results revealed that 10.6±0.0% of total ash, 8.4±0.0% of water soluble ash 0.65±0.01% of acid insoluble ash 11.0±0.1% of cold ethanol extractable matter, 13.9±0.1% hot ethanol extractable matter, 13.9±0.1% cold water extractable matter and 20.2±0.2% hot water extractable matter were present in the Sarasvatha Choorna. Pathogenic microorganisms such as Coliforms, Escherichia coli and Salmonella were not found and heavy metal concentrations of Sarasvatha Choorna were well below the recommended upper limits for the tested heavy metals. Phytochemical screening studies revealed the presence of flavonoids, steroid glycosides and coumarins in both water and ethanol extracts of Sarasvatha Choorna. Presence of the raw materials in the Sarasvatha Choorna was confirmed by TLC fingerprints. Present study reveals the quality of Sarasvatha Choorna for the first time and quality control parameters resulted from this study can be used as a reference standard for quality control of Sarasvatha Choorna.
| Published in | American Journal of Clinical and Experimental Medicine (Volume 3, Issue 5) |
| DOI | 10.11648/j.ajcem.20150305.26 |
| Page(s) | 288-292 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Sarasvatha Choorna, Dementia, Standardization, Quality Control
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APA Style
T. D. N. Karunaratne, Kahapola Sugataratana, H. A. S. Ariyawansa, H. A. de Silva, K. Samarasingha, et al. (2015). Standardization of Sarasvatha Choorna: Used as a Remedy for Dementia. American Journal of Clinical and Experimental Medicine, 3(5), 288-292. https://doi.org/10.11648/j.ajcem.20150305.26
ACS Style
T. D. N. Karunaratne; Kahapola Sugataratana; H. A. S. Ariyawansa; H. A. de Silva; K. Samarasingha, et al. Standardization of Sarasvatha Choorna: Used as a Remedy for Dementia. Am. J. Clin. Exp. Med. 2015, 3(5), 288-292. doi: 10.11648/j.ajcem.20150305.26
AMA Style
T. D. N. Karunaratne, Kahapola Sugataratana, H. A. S. Ariyawansa, H. A. de Silva, K. Samarasingha, et al. Standardization of Sarasvatha Choorna: Used as a Remedy for Dementia. Am J Clin Exp Med. 2015;3(5):288-292. doi: 10.11648/j.ajcem.20150305.26
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Download@article{10.11648/j.ajcem.20150305.26,
author = {T. D. N. Karunaratne and Kahapola Sugataratana and H. A. S. Ariyawansa and H. A. de Silva and K. Samarasingha and L. D. A. M. Arawwawala},
title = {Standardization of Sarasvatha Choorna: Used as a Remedy for Dementia},
journal = {American Journal of Clinical and Experimental Medicine},
volume = {3},
number = {5},
pages = {288-292},
doi = {10.11648/j.ajcem.20150305.26},
url = {https://doi.org/10.11648/j.ajcem.20150305.26},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20150305.26},
abstract = {Sri Lanka has been recognized as one of the fastest aging populations from the developing countries. There is a large senior population in the country. Since age is the biggest risk factor for Dementia, the need to create awareness and management is an increasing necessity. Sarasvatha Choorna is one of the polyherbal preparation used in Ayurveda for the management of Dementia which consists of 12 medicinal plants. In the present study, an attempt was made to standardize Sarasvatha Choorna by using standard protocols. Standardization was carried out by determination of total ash, water soluble ash, acid insoluble ash, microbial counts, heavy metals, phytochemical screening and development of TLC-densitogram fingerprints. Results revealed that 10.6±0.0% of total ash, 8.4±0.0% of water soluble ash 0.65±0.01% of acid insoluble ash 11.0±0.1% of cold ethanol extractable matter, 13.9±0.1% hot ethanol extractable matter, 13.9±0.1% cold water extractable matter and 20.2±0.2% hot water extractable matter were present in the Sarasvatha Choorna. Pathogenic microorganisms such as Coliforms, Escherichia coli and Salmonella were not found and heavy metal concentrations of Sarasvatha Choorna were well below the recommended upper limits for the tested heavy metals. Phytochemical screening studies revealed the presence of flavonoids, steroid glycosides and coumarins in both water and ethanol extracts of Sarasvatha Choorna. Presence of the raw materials in the Sarasvatha Choorna was confirmed by TLC fingerprints. Present study reveals the quality of Sarasvatha Choorna for the first time and quality control parameters resulted from this study can be used as a reference standard for quality control of Sarasvatha Choorna.},
year = {2015}
}
TY - JOUR T1 - Standardization of Sarasvatha Choorna: Used as a Remedy for Dementia AU - T. D. N. Karunaratne AU - Kahapola Sugataratana AU - H. A. S. Ariyawansa AU - H. A. de Silva AU - K. Samarasingha AU - L. D. A. M. Arawwawala Y1 - 2015/11/26 PY - 2015 N1 - https://doi.org/10.11648/j.ajcem.20150305.26 DO - 10.11648/j.ajcem.20150305.26 T2 - American Journal of Clinical and Experimental Medicine JF - American Journal of Clinical and Experimental Medicine JO - American Journal of Clinical and Experimental Medicine SP - 288 EP - 292 PB - Science Publishing Group SN - 2330-8133 UR - https://doi.org/10.11648/j.ajcem.20150305.26 AB - Sri Lanka has been recognized as one of the fastest aging populations from the developing countries. There is a large senior population in the country. Since age is the biggest risk factor for Dementia, the need to create awareness and management is an increasing necessity. Sarasvatha Choorna is one of the polyherbal preparation used in Ayurveda for the management of Dementia which consists of 12 medicinal plants. In the present study, an attempt was made to standardize Sarasvatha Choorna by using standard protocols. Standardization was carried out by determination of total ash, water soluble ash, acid insoluble ash, microbial counts, heavy metals, phytochemical screening and development of TLC-densitogram fingerprints. Results revealed that 10.6±0.0% of total ash, 8.4±0.0% of water soluble ash 0.65±0.01% of acid insoluble ash 11.0±0.1% of cold ethanol extractable matter, 13.9±0.1% hot ethanol extractable matter, 13.9±0.1% cold water extractable matter and 20.2±0.2% hot water extractable matter were present in the Sarasvatha Choorna. Pathogenic microorganisms such as Coliforms, Escherichia coli and Salmonella were not found and heavy metal concentrations of Sarasvatha Choorna were well below the recommended upper limits for the tested heavy metals. Phytochemical screening studies revealed the presence of flavonoids, steroid glycosides and coumarins in both water and ethanol extracts of Sarasvatha Choorna. Presence of the raw materials in the Sarasvatha Choorna was confirmed by TLC fingerprints. Present study reveals the quality of Sarasvatha Choorna for the first time and quality control parameters resulted from this study can be used as a reference standard for quality control of Sarasvatha Choorna. VL - 3 IS - 5 ER -
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