Androgen Insensitivity Syndrome- A Case Report
American Journal of Clinical and Experimental Medicine
Volume 3, Issue 4, July 2015, Pages: 133-136
Received: May 10, 2015; Accepted: May 17, 2015; Published: May 29, 2015
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Tarafdar Runa Laila, Department of Obstetrics & Gynaecology, University Kuala Lumpur, Royal College of Medicine Perak, Ipoh, Perak, Malaysia
Sheikh Salahuddin Ahmed, Department of Internal Medicine, University Kuala Lumpur, Royal College of Medicine Perak, Ipoh, Perak, Malaysia
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Androgen insensitivity syndrome is a disorder where there is resistance to androgen actions influencing both the morphogenesis and differentiation of androgen responsive body structures. It occurs due to an X-linked mutation in Androgen Receptor gene. This disorder includes a spectrum of changes ranging from male infertility to completely normal female external genitalia in a chromosomally male individual. These cases need proper diagnosis and appropriate management. We report this case for its interesting presentation. The patient is a 20 year old female, presented with bilateral labial swellings and primary amenorrhoea. Subsequent investigations were done which revealed that the patient is a genetically male with absence of female internal genitalia but presence of testes. Gonadectomy was done after proper counseling and was put on hormone replacement therapy. Proper psychological support was also given to her, which is more important.
Androgen Insensitivity Syndrome, Primary Amenorrhoea, Testicular Feminization Syndrome
To cite this article
Tarafdar Runa Laila, Sheikh Salahuddin Ahmed, Androgen Insensitivity Syndrome- A Case Report, American Journal of Clinical and Experimental Medicine. Vol. 3, No. 4, 2015, pp. 133-136. doi: 10.11648/j.ajcem.20150304.11
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